Xuelian Du

Works (2)

Updated: July 5th, 2023 15:56
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2010 journal article

Improving the catalytic activity of hyperthermophilic Pyrococcus prolidases for detoxification of organophosphorus nerve agents over a broad range of temperatures

Applied Microbiology and Biotechnology, 87(5), 1715–1726.

By: C. Theriot n, X. Du n, S. Tove n & A. Grunden n 

author keywords: Prolidase; Pyrococcus furiosus; OP nerve agents; Mutagenesis; Directed evolution
MeSH headings : Amino Acid Substitution / genetics; Archaeal Proteins / chemistry; Archaeal Proteins / genetics; Archaeal Proteins / isolation & purification; Archaeal Proteins / metabolism; Chemical Warfare Agents / metabolism; Culture Media / chemistry; Dipeptidases / chemistry; Dipeptidases / genetics; Dipeptidases / isolation & purification; Dipeptidases / metabolism; Enzyme Stability; Escherichia coli / genetics; Models, Molecular; Mutagenesis; Organophosphorus Compounds / metabolism; Pesticides / metabolism; Plasmids; Polymerase Chain Reaction / methods; Protein Stability; Protein Structure, Tertiary; Pyrococcus furiosus / enzymology; Pyrococcus furiosus / genetics; Sequence Deletion; Temperature
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2005 journal article

Characterization of the dinuclear metal center of Pyrococcus furiosus prolidase by analysis of targeted mutants

FEBS LETTERS, 579(27), 6140–6146.

By: X. Du*, S. Tove, K. Kast-Hutcheson & A. Grunden* 

author keywords: prolidase; aminopeptidase; dinuclear metal center; cobalt enzyme; Pyrococcus furiosus
MeSH headings : Archaeal Proteins / chemistry; Archaeal Proteins / genetics; Binding Sites; Catalysis; Cobalt / chemistry; Dipeptidases / chemistry; Dipeptidases / genetics; Mutation; Pyrococcus furiosus / enzymology
Sources: Web Of Science, ORCID
Added: August 6, 2018