Emilie Despagnet Smith

Works (7)

Updated: July 5th, 2023 15:56

2010 patent

Regiospecific synthesis of nicotine derivatives

By: L. King, E. Smith & D. Comins

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Synthesis of nicotine derivatives from nicotine

By: D. Comins & E. Smith

Source: NC State University Libraries
Added: August 6, 2018

2006 article

A six-step synthesis of (S)-5-ethenyl-3-(1-methyl-2-pyrrolidinyl)pyridine (SIB-1508Y) from (S)-nicotine

Comins, D. L., & Smith, E. D. (2006, January 10). Tetrahedron Letters.

By: D. Comins n & E. Smith n

topics (OpenAlex): Nicotinic Acetylcholine Receptors Study; Synthesis and Biological Evaluation; Chemical synthesis and alkaloids
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Source: Web Of Science
Added: August 6, 2018

2006 patent

Regioselective halogenation of nicotine and substituted nicotines

Washington, DC: U.S. Patent and Trademark Office.

By: D. Comins, F. Fevrier & E. Smith

Source: NC State University Libraries
Added: August 6, 2018

2006 patent

Regiospecific synthesis of nicotine derivatives

Washington, DC: U.S. Patent and Trademark Office.

By: L. King, E. Smith & D. Comins

Source: NC State University Libraries
Added: August 6, 2018

2006 patent

Synthesis of nicotine derivatives from nicotine

Washington, DC: U.S. Patent and Trademark Office.

By: D. Comins & E. Smith

Source: NC State University Libraries
Added: August 6, 2018

2005 article

Synthesis of Nicotine Derivatives via Reductive Disilylation of (S)-Nicotine

Smith, E. D., Février, F. C., & Comins, D. L. (2005, December 22). Organic Letters.

By: E. Smith n, F. Février n & D. Comins n

MeSH headings : Catalysis; Lithium / chemistry; Molecular Structure; Nicotine / analogs & derivatives; Nicotine / chemical synthesis; Nicotine / chemistry; Oxidation-Reduction; Silanes / chemistry; Stereoisomerism
topics (OpenAlex): Nicotinic Acetylcholine Receptors Study; Synthesis and Biological Evaluation; Radical Photochemical Reactions
TL;DR: A variety of novel nicotine derivatives were prepared via reductive disilylation of (S)-nicotine via addition of various carbonyl electrophiles and a catalytic amount of TBAF provided either C-5 substituted nicotines or 1,4-dihydronicotine derivatives. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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