@article{frederico_gerard_pinto_gradil_2007, title={Bilateral occurrence of granulosa-theca cell tumors in an Arabian mare}, volume={48}, number={5}, journal={Canadian Veterinary Journal}, author={Frederico, L. M. and Gerard, M. P. and Pinto, C. R. F. and Gradil, C. M.}, year={2007}, pages={502–505} } @article{tuttle_frederico_linder_gunkel_remick_redding_2007, title={Pathological fracture of the ulna due to osteosarcoma in an Arabian camel (Camelus dromedarius)}, volume={161}, ISSN={["0042-4900"]}, DOI={10.1136/vr.161.1.30}, abstractNote={OSTEOSARCOMA, a malignant mesenchymal neoplasia originating within bone, occurs only rarely in large animal species (Cotchin 1960, 1977, Pascoe and Summers 1981, Pool 1998). The long bones are the primary site for osteosarcoma in small animals, while in large animals the common sites are generally the skull and mandible (Thorpe and Graham 1934, Pospischil and others 1982, Livesey and Wilkie 1986, Steinberg and George 1989, Plumlee and others 1993, Pool 1998, Perez-Martinez and others 1999), although osteosarcomas have been reported to affect the pelvis, vertebrae, ribs and, rarely, the appendicular skeleton in domestic ruminants and equine species (Heimann 1975, Rosenberger 1975, Livesey and Wilkie 1986, Zaruby and others 1993, Wan and others 1994, Nelson and Baker 1998, Jenner and others 2003). This short communication describes a case of pathological fracture secondary to osteosarcoma in an Arabian camel (Camelus dromedarius). A seven-year-old intact female Arabian camel was presented to the North Carolina State University’s College of Veterinary Medicine Veterinary Teaching Hospital for evaluation of a left forelimb lameness of three days’ duration. The camel was found at pasture with an acute, non-weight-bearing lameness on the left forelimb, which was swollen in the radiohumeral region. Treatment with butorphanol (0·06 mg/kg orally every 24 hours), diazepam (0·02 mg/kg orally every 24 hours), and a single oral dose of 1·1 mg/kg flunixin meglumine had been administered by the referring veterinarian. The camel had calved eight months previously, and had given birth to one other calf before that, but had no other significant medical history. Upon arrival, the camel was quiet and dull, with a normal rectal temperature (37·7°C, reference range 36·4 to 42°C), tachycardia (88 bpm, reference range 40 to 50 bpm) and tachypnoea (28 breaths/minute, reference range 5 to 12 breaths/minute). Auscultation of the heart and lungs revealed no audible abnormalities. The faeces were soft, and adequate borborygmi were audible in all four abdominal quadrants. The body condition score was 4/9. Severe lameness (grade 4/5) was apparent in the left forelimb, with moderate swelling around the left elbow. Radiographs of the left radiohumeral joint revealed a cranially displaced oblique articular fracture involving the proximal ulna. The fracture line extended from the trochlear notch to the caudal surface of the ulna distal to the olecranon. Slight radiolucencies were noted in the bone at the cranial edge of the fracture (Figs 1, 2). Cranial displacement of the distal radius and ulna had resulted in subluxation of the radiohumeral joint. A complete blood count revealed mild anaemia (packed-cell volume 21 per cent, reference range 24 to 42 per cent) and a regenerative neutrophilia (white blood cell count 19·8 x 103 cells/μl [reference range 2·9 x 103 to 9·7 x 103 cells/μl]; absolute numbers of bands 0·2 x 103 cells/μl [the presence of any bands is considered abnormal]). A serum chemistry panel revealed mildly elevated levels of globulin (46 g/l, reference range 28 to 44 g/l) and gamma glutyltransferase (39·0 iu/l, reference range 0 to 20 iu/l), Veterinary Record (2007) 161, 30-33}, number={1}, journal={VETERINARY RECORD}, author={Tuttle, A. D. and Frederico, L. and Linder, K. and Gunkel, C. and Remick, A. and Redding, R.}, year={2007}, month={Jul}, pages={30–33} } @article{poulsen_elce_frederico_remick_capucille_2006, title={Atresia coli in an alpaca cria}, volume={158}, ISSN={["0042-4900"]}, DOI={10.1136/vr.158.17.598}, abstractNote={anaesthesia, an anastomosis to treat the atresia would have been extremely difficult because of the length of the atresic portion. Gross postmortem examination revealed no additional abnormal findings, but defined the extent of the atresia (Fig 2). Histopathology was not performed. Congenital anomalies in alpacas are not well described in the literature, nor are they thoroughly understood by veterinarians and alpaca owners. There has been one case of anorectal atresia and rectovaginal fistula in an alpaca in Australia (Carraro and others 1996). This malformation was corrected surgically when the alpaca was a neonate, and the animal was reported to be thriving at nine months of age. Atresia coli is corrected surgically with an end-to-end, side-to-side or end-to-side anastomosis of the proximal blind end of the colon to the descending colon, without removal of the atresic portion of bowel (Smith 1982, Smith and others 1991). The prognosis is poor to fair for animals undergoing surgery, with short-term survival rates of 43 to 71 per cent (Ducharme and others 1988, Constable and others 1989, Atresia coli in an alpaca cria}, number={17}, journal={VETERINARY RECORD}, author={Poulsen, KP and Elce, YA and Frederico, LM and Remick, AK and Capucille, DJ}, year={2006}, month={Apr}, pages={598–599} } @article{frederico_jones_blikslager_2006, title={Predisposing factors for small colon impaction in horses and outcome of medical and surgical treatment: 44 cases (1999–2004)}, volume={229}, ISSN={0003-1488}, url={http://dx.doi.org/10.2460/javma.229.10.1612}, DOI={10.2460/javma.229.10.1612}, abstractNote={Abstract Objective—To identify factors associated with development of small colon impaction in horses and with selection of medical versus surgical treatment and to determine the prognosis for affected horses following medical or surgical management. Design—Retrospective case series. Animals—44 horses with primary impaction of the small colon. Procedures—Medical records were reviewed for signalment, history, clinical findings, treatment (medical vs surgical), hospitalization time, and outcome. For comparison purposes, the same information was collected for 83 horses with primary impaction of the large colon. Results—Diarrhea was the only factor found to be associated with development of small colon impaction. Horses with small colon impaction were 10.8 times as likely to have diarrhea at the time of initial examination as were horses with large colon impaction. Abdominal distension was the only factor associated with use of surgical versus medical treatment. Horses with small colon impaction that were treated surgically were 5.2 times as likely to have had abdominal distension at the time of admission as were horses with small colon impaction that were treated medically. Overall, 21 of 23 (91%) horses treated medically and 20 of 21 (95%) horses treated surgically survived to discharge. Conclusions and Clinical Relevance—Results suggest that diarrhea may be a risk factor for development of small colon impaction and that horses with small colon impaction that have abdominal distension at the time of initial examination are more likely to require surgical than medical treatment.}, number={10}, journal={Journal of the American Veterinary Medical Association}, publisher={American Veterinary Medical Association (AVMA)}, author={Frederico, Lisa M. and Jones, Samuel L. and Blikslager, Anthony T.}, year={2006}, month={Nov}, pages={1612–1616} }