Usharani Mudiganti

Works (3)

Updated: July 5th, 2023 15:48

2010 article

Insect response to alphavirus infection—Establishment of alphavirus persistence in insect cells involves inhibition of viral polyprotein cleavage

Mudiganti, U., Hernandez, R., & Brown, D. T. (2010, March 9). Virus Research.

By: U. Mudiganti n, R. Hernandez n & D. Brown n

author keywords: Arbovirus; Sindbis; Insect cells; Microarray; Persistent infection
MeSH headings : Alphavirus / pathogenicity; Alphavirus / physiology; Animals; Cell Line; Drosophila; Polyproteins / metabolism; Viral Proteins / metabolism; Virus Replication
topics (OpenAlex): Invertebrate Immune Response Mechanisms; Mosquito-borne diseases and control; Insect symbiosis and bacterial influences
TL;DR: It is proposed that inefficient cleavage of the polyprotein may lead to reduced levels of virus seen as persistence is established, and the up-regulation of a wide-spectrum protease inhibitor, Thiol-ester containing Protein (TEP) II is confirmed. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2006 article

A colorimetric assay for viral agents that produce cytopathic effects

Ruben Carbonell; Usharani Mudiganti; Caryn L. Heldt; Dennis Brown; Raquel Hernandez; Patrick Gurgel

topics (OpenAlex):
Source: NC State University Libraries
Added: August 6, 2018

2006 article

Sindbis virus infection of two model insect cell systems—A comparative study

Mudiganti, U., Hernandez, R., Ferreira, D., & Brown, D. T. (2006, July 19). Virus Research.

By: U. Mudiganti n, R. Hernandez n, D. Ferreira n & D. Brown n

MeSH headings : Animals; Cell Line; Cell Shape; Cell Survival; Culicidae; Cytopathogenic Effect, Viral; Drosophila; Microscopy, Electron, Transmission; Sindbis Virus / growth & development; Viral Plaque Assay
topics (OpenAlex): Invertebrate Immune Response Mechanisms; Insect symbiosis and bacterial influences; Mosquito-borne diseases and control
TL;DR: A comparative study of Sindbis virus infection of Schnieder-2 Drosophila (S2) cells to cells of the mosquito Aedes albopictus (clone U4.4) was undertaken, establishing S2 cells as an additional invertebrate model system to study the interactions of an invertebrates host with Sindbisirus. (via Semantic Scholar)
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Source: NC State University Libraries
Added: August 6, 2018

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