Works (12)

Updated: July 5th, 2023 16:04

2010 journal article

Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor

Toxicology and Applied Pharmacology, 245(3), 335–343.

By: R. Casabar, P. Das, G. DeKrey, C. Gardiner, Y. Cao, R. Rose, A. Wallace

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Lysine 419 targets human glucocorticoid receptor for proteasomal degradation

Steroids, 75(12), 1016–1023.

By: A. Wallace, Y. Cao, S. Chandramouleeswaran & J. Cidlowski

Source: NC State University Libraries
Added: August 6, 2018

2006 article

Fipronil induces CYP isoforms and cytotoxicity in human hepatocytes

Das, P. C., Cao, Y., Cherrington, N., Hodgson, E., & Rose, R. L. (2006, December 15). CHEMICO-BIOLOGICAL INTERACTIONS, Vol. 164, pp. 200–214.

By: P. Das n, Y. Cao n, N. Cherrington*, E. Hodgson n & R. Rose n

author keywords: fipronil; human hepatic and HepG2 cells; CYP3A4; CYP2B6; CYP1A1; cytotoxicity; apoptosis
MeSH headings : Caspase 3 / metabolism; Caspase 7 / metabolism; Cell Survival / drug effects; Cells, Cultured; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Enzyme Induction / drug effects; Gene Expression Regulation; Hepatocytes / drug effects; Hepatocytes / enzymology; Humans; Isoenzymes / genetics; Isoenzymes / metabolism; Pyrazoles / chemistry; Pyrazoles / pharmacology; RNA, Messenger / genetics; Sulfur / chemistry; Transcription, Genetic / genetics; fas Receptor / metabolism
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Development of an ELISA for the detection of bromoxynil in water

ENVIRONMENT INTERNATIONAL, 31(1), 33–42.

By: Y. Cao*, Y. Lu*, S. Long n, J. Hong* & G. Sheng*

author keywords: ELISA; bromoxynil; 2,6-dibromo-4-cyanophenoxyacetic acid; cross-reactivity; water analysis
MeSH headings : Animals; Bromobenzenes / chemical synthesis; Bromobenzenes / immunology; Cross Reactions; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay / methods; Female; Haptens / immunology; Herbicides / analysis; Herbicides / immunology; Hydrogen-Ion Concentration; Immune Sera / biosynthesis; Immune Sera / immunology; Immunization; Male; Nitriles / analysis; Nitriles / immunology; Polysorbates; Rabbits; Reproducibility of Results; Rivers / chemistry; Water / analysis
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Pesticide metabolism in humans, including polymorphisms

Scandinavian Journal of Work, Environment & Health, 31, 156–163.

By: R. Rose, J. Tang, J. Choi, Y. Cao, A. Usmani, N. Cherrington, E. Hodgson

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

In vitro metabolism of carbaryl by human cytochrome P450 and its inhibition by chlorpyrifos

CHEMICO-BIOLOGICAL INTERACTIONS, 141(3), 229–241.

By: J. Tang n, Y. Cao n, R. Rose n & E. Hodgson n

author keywords: carbaryl; human lifer microsomes; metabolism
MeSH headings : Adult; Carbaryl / metabolism; Cells, Cultured; Chlorpyrifos / pharmacology; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System / metabolism; Dose-Response Relationship, Drug; Female; Humans; Hydroxylation / drug effects; Insecticides / metabolism; Insecticides / pharmacology; Isoenzymes / antagonists & inhibitors; Isoenzymes / metabolism; Kinetics; Male; Microsomes, Liver; Molecular Structure
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Metabolism of chlorpyrifos by human cytochrome P450 isoforms and human, mouse, and rat liver microsomes

Drug Metabolism and Disposition, 29(9), 1201–1204.

By: J. Tang, Y. Cao, R. Rose, A. Brimfield, D. Dai, J. Goldstein, E. Hodgson

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene, vinclozolin, and flutamide

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 70(3), 127–141.

By: D. Dai*, Y. Cao n, G. Falls*, P. Levi n, E. Hodgson n & R. Rose n

Source: Web Of Science
Added: August 6, 2018

2000 journal article

Flavin-containing monooxygenase isoform specificity for the N-oxidation of tamoxifen determined by product measurement and NADPH oxidation

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 14(2), 118–120.

By: E. Hodgson n, R. Rose n, Y. Cao n, S. Dehal* & D. Kupfer*

author keywords: flavin-containing monooxygenase; FMO; FMO isoforms; tamoxifen; human; mouse
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Flavin-containing monooxygenase and cytochrome P450 mediated metabolism of pesticides: from mouse to human

Reviews in Toxicology, 2(1998), 231–243.

By: E. Hodgson, N. Cherrington, S. Coleman, S. Liu, J. Falls, Y. Cao, J. Goldstein, R. Rose

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3 and 5

XENOBIOTICA, 28(7), 673–682.

By: N. Cherrington n, Y. Cao n, J. Cherrington n, R. Rose n & E. Hodgson n

MeSH headings : Adult; Animals; Female; Humans; Liver / embryology; Liver / metabolism; Male; Mice; Microsomes, Liver / metabolism; Middle Aged; Oxygenases / biosynthesis; Rats; Sex Characteristics; Species Specificity
Source: Web Of Science
Added: August 6, 2018

1997 article

Regulation of mouse liver flavin-containing monooxygenases 1 and 3 by sex steroids

Falls, J. G., Ryu, D. Y., Cao, Y., Levi, P. E., & Hodgson, E. (1997, June 15). ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Vol. 342, pp. 212–223.

By: J. Falls n, D. Ryu n, Y. Cao n, P. Levi n & E. Hodgson n

author keywords: flavin-containing monooxygenases; FM01; FM03; FM05; FMO expression; hormonal regulation; testosterone; 17 beta-estradiol; progesterone
MeSH headings : Animals; Blotting, Western; Castration; Estradiol / blood; Estradiol / pharmacology; Female; Gene Expression Regulation, Enzymologic; Isoenzymes / metabolism; Liver / drug effects; Liver / enzymology; Male; Mice; Mice, Inbred Strains; Microsomes, Liver / metabolism; Organ Size / drug effects; Ovariectomy; Oxygenases / metabolism; Progesterone / blood; Progesterone / pharmacology; RNA, Messenger / metabolism; Seminal Vesicles / drug effects; Testosterone / blood; Testosterone / pharmacology; Uterus / drug effects
Source: Web Of Science
Added: August 6, 2018