Works (1)
Updated: July 5th, 2023 15:55
2006 journal article
Cerebrospinal fluid is an efficient route for establishing brain infection with feline immunodeficiency virus and transfering infectious virus to the periphery
JOURNAL OF NEUROVIROLOGY, 12(4), 294–306.
author keywords: dementia; HIV; macrophages; T cells; viremia
MeSH headings : Animals; Brain Diseases / cerebrospinal fluid; Brain Diseases / immunology; Brain Diseases / virology; Cats; DNA, Viral / isolation & purification; Feline Acquired Immunodeficiency Syndrome / cerebrospinal fluid; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Immunodeficiency Virus, Feline / genetics; Immunodeficiency Virus, Feline / isolation & purification; Lymphocyte Subsets / immunology; Macrophages / immunology; Macrophages / virology; RNA, Viral / blood; RNA, Viral / cerebrospinal fluid; Viral Load
TL;DR:
Results indicate that free FIV circulating in the CSF promotes infection of the CNS and provides a highly efficient pathway for the transfer of infectious virus to the periphery.
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Added: August 6, 2018
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