Works (8)

Updated: July 25th, 2023 21:15

2013 journal article

De novo Sequencing, Characterization, and Comparison of Inflorescence Transcriptomes of Cornus canadensis and C. florida (Cornaceae)

PLoS ONE, 8(12), e82674.

By: J. Zhang n, R. Franks n, X. Liu n, M. Kang*, J. Keebler n, J. Schaff n, H. Huang*, Q. Xiang n

Contributors: J. Zhang n, R. Franks n, X. Liu n, M. Kang*, J. Keebler n, J. Schaff n, H. Huang*, Q. Xiang n

Ed(s): T. Wang

MeSH headings : Chromosome Mapping; Cornus / genetics; Cornus / growth & development; DNA, Complementary / chemistry; Flowers / genetics; Flowers / growth & development; Gene Library; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Transcriptome
TL;DR: The study identified putative candidates potentially involved in the genetic regulation of inflorescence evolution and/or disease resistance in dogwoods for future analyses, and built a preliminary source of genome sequence data. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

A population genetic approach to mapping neurological disorder genes using deep resequencing

PLoS Genetics, 7(2).

By: R. Myers, F. Casals, J. Gauthier, F. Hamdan, J. Keebler, A. Boyko, C. Bustamante, A. Piton ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Variation in genome-wide mutation rates within and between human families

Nature Genetics, 43(7), 712–137.

By: D. Conrad, J. Keebler, M. DePristo, S. Lindsay, Y. Zhang, F. Casals, Y. Idaghdour, C. Hartl ...

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Direct measure of the de novo mutation rate in autism and schizophrenia cohorts

American Journal of Human Genetics, 87(3), 316–324.

By: P. Awadalla, J. Gauthier, R. Myers, F. Casals, F. Hamdan, A. Griffing, M. Cote, E. Henrion ...

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Selection shapes malaria genomes and drives divergence between pathogens infecting hominids versus rodents

BMC Evolutionary Biology, 8.

By: F. Prugnolle, K. Mcgee, J. Keebler & P. Awadalla

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome

NATURE GENETICS, 39(1), 126–130.

By: J. Mu*, P. Awadalla n, J. Duan*, K. McGee n, J. Keebler n, K. Seydel*, G. McVean*, X. Su*

MeSH headings : Animals; Antigens, Protozoan / genetics; Antigens, Protozoan / isolation & purification; Antigens, Protozoan / metabolism; Cell-Free System / metabolism; Chromosome Mapping; Drug Delivery Systems; Drug Design; Drug Resistance / genetics; Genetic Variation; Genome, Protozoan; Humans; Immune Sera / chemistry; Malaria Vaccines / immunology; Malaria, Falciparum / immunology; Malaria, Falciparum / parasitology; Plasmodium falciparum / genetics; Plasmodium falciparum / immunology
TL;DR: This work surveyed P. falciparum genes for polymorphisms and identified various highly polymorphic loci and genes, some of which encode new antigens that are confirmed using human immune sera and providing urgently needed vaccine candidates for disease control. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Structural polymorphism and diversifying selection on the pregnancy malaria vaccine candidate VAR2CSA

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 155(2), 103–112.

By: J. Bockhorst*, F. Lu*, J. Janes*, J. Keebler n, B. Gamain*, P. Awadalla n, X. Su*, R. Samudrala*, N. Jojica, J. Smith*

author keywords: antigenic variation; malaria; Plasmodium falciparum; var genes
MeSH headings : Animals; Antigens, Protozoan / chemistry; Antigens, Protozoan / genetics; Antigens, Protozoan / immunology; Computational Biology / methods; DNA, Protozoan / chemistry; DNA, Protozoan / genetics; Female; Geography; Humans; Malaria / immunology; Malaria / parasitology; Malaria Vaccines / immunology; Models, Molecular; Molecular Sequence Data; Phylogeny; Plasmodium falciparum / genetics; Plasmodium falciparum / isolation & purification; Polymorphism, Genetic; Pregnancy; Pregnancy Complications, Parasitic / immunology; Pregnancy Complications, Parasitic / prevention & control; Protein Structure, Tertiary; Selection, Genetic; Sequence Analysis, DNA; Sequence Homology, Amino Acid
TL;DR: A novel phylogenetic approach is developed that incorporates recombination and tracks new mutations in segment types in the VAR2CSA Duffy binding-like (DBL) adhesion domains and validate a new approach to modeling protein evolution in the presence of frequent recombination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

A murine specific expansion of the Rhox cluster involved in embryonic stem cell biology is under natural selection

BMC Genomics, 7.

By: M. Jackson, A. Watt, P. Gautier, D. Gilchrist, J. Driehaus, G. Graham, J. Keebler, F. Prugnolle, P. Awadalla, L. Forrester

Source: NC State University Libraries
Added: August 6, 2018

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