Lenore Anderson Mohammadian

Works (1)

Updated: August 16th, 2023 21:17

2006 journal article

A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral Doxil extravasation

CLINICAL CANCER RESEARCH, 12(22), 6800–6807.

By: M. Kleiter*, D. Yu, L. Mohammadian*, N. Niehaus, I. Spasojevic *, L. Sanders*, B. Viglianti *, P. Yarmolenko* ...

MeSH headings : Animals; Antibiotics, Antineoplastic / pharmacokinetics; Antibiotics, Antineoplastic / therapeutic use; Combined Modality Therapy / methods; Diagnostic Imaging / methods; Dose-Response Relationship, Drug; Doxorubicin / pharmacokinetics; Doxorubicin / therapeutic use; Drug Carriers / administration & dosage; Feasibility Studies; Female; Fibrosarcoma / therapy; Hyperthermia, Induced / methods; Liposomes / administration & dosage; Liposomes / pharmacokinetics; Radioactive Tracers; Rats; Technetium Tc 99m Exametazime / administration & dosage; Thigh / radiation effects; Tumor Cells, Cultured; Xenograft Model Antitumor Assays
TL;DR: The use of a radiolabeled tracer has potential value to monitor drug delivery and estimate the effect of an intervention aimed to increase liposomal accumulation, such as local hyperthermia. (via Semantic Scholar)
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