Works (8)
Updated: July 28th, 2023 21:16
2010 journal article
Melt Spun Microporous Fibers Using Poly(lactic acid) and Sulfonated Copolyester Blends for Tissue Engineering Applications
JOURNAL OF APPLIED POLYMER SCIENCE, 117(6), 3350–3361.
author keywords: biomaterials; blends; fibers; water soluble polymers
TL;DR:
Results show that SP can be successfully used in a blend with PLA to produce microporous fibers to fabricate three-dimensional nonwoven scaffolds for tissue engineering applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Modulation of collagen gel compaction by extracellular ATP is MAPK and NF-kappa B pathways dependent
EXPERIMENTAL CELL RESEARCH, 315(11), 1990–2000.
author keywords: ATP; Collagen gel; P2 receptor; bone; NF-kappa B; MAPK; Prestress
MeSH headings : 3T3 Cells; Adenosine Triphosphate / metabolism; Adenosine Triphosphate / pharmacology; Adenylyl Cyclases / metabolism; Animals; Base Sequence; Calmodulin / metabolism; Collagen / genetics; Collagen / metabolism; DNA Primers / genetics; Extracellular Fluid / metabolism; Gels; Gene Expression / drug effects; Kinetics; MAP Kinase Signaling System; Mechanotransduction, Cellular; Mice; Models, Biological; Myosin-Light-Chain Kinase / metabolism; NF-kappa B / metabolism; Osteoblasts / cytology; Osteoblasts / drug effects; Osteoblasts / metabolism; Phosphatidylinositol 3-Kinases / metabolism; Receptors, Purinergic P2 / metabolism; Stress, Mechanical
TL;DR:
The results from the present and previous studies indicate that extracellular ATP may act as a negative feedback modulator in the mechanotransduction system since mechanical stimuli increase ATP release from stimulated cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Expression of Proinflammatory Cytokines by Human Mesenchymal Stem Cells in Response to Cyclic Tensile Strain
JOURNAL OF CELLULAR PHYSIOLOGY, 219(1), 77–83.
Contributors: *, T. Pfeiler*, N. Monteiro-Riviere n & E. Loboa*
MeSH headings : Animals; Bone Marrow Cells / cytology; Bone Marrow Cells / physiology; Cells, Cultured; Cytokines / metabolism; Humans; Interleukin-1beta / metabolism; Interleukin-6 / metabolism; Interleukin-8 / metabolism; Male; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Stress, Mechanical; Stress, Physiological; Tensile Strength; Tumor Necrosis Factor-alpha / metabolism; Young Adult
TL;DR:
IL‐6 and IL‐8 expressions by hMSCs were induced by cyclic tensile strain and osteogenic differentiating media, indicating that IL‐ 6 andIL‐8 may be functioning as autocrine signals during osteogenic differentiation of h MSCs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 journal article
Finite element modeling of 3D human mesenchymal stem cell-seeded collagen matrices exposed to tensile strain
JOURNAL OF BIOMECHANICS, 41(10), 2289–2296.
author keywords: uniaxial tensile strain; HMSCs; collagen; bioreactor; finite element modeling
MeSH headings : Biomechanical Phenomena / methods; Bioreactors; Cell Lineage; Cells, Cultured; Collagen / chemistry; Cytoskeleton / metabolism; Finite Element Analysis; Humans; Mesenchymal Stem Cells / cytology; Models, Theoretical; Pressure; Stress, Mechanical; Tensile Strength; Tissue Engineering / methods
TL;DR:
Finite element models were created to evaluate the local loading conditions on bone marrow-derived hMSCs seeded in three-dimensional collagen matrices exposed to cyclic tensile strain and it was determined that globally applied uniaxial tensile strains of 10% and 12% resulted in local strains up to 18.3% and 21.8%, respectively.
(via Semantic Scholar)
open access via europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Mesenchymal stem cell-seeded collagen matrices for bone repair: Effects of cyclic tensile strain, cell density, and media conditions on matrix contraction in vitro
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 88A(3), 778–786.
author keywords: bone tissue engineering; mechanical stimulation; osteogenic differentiation; collagen contraction; mesenchymal stem cells
MeSH headings : Adult; Bone and Bones / cytology; Cell Culture Techniques / methods; Cell Differentiation; Cell Survival; Collagen; Culture Media, Conditioned; Humans; Male; Mesenchymal Stem Cells / cytology; Tensile Strength
TL;DR:
Findings suggest a correlation between hMSC proliferation and osteogenic differentiation on collagen matrix contraction that is affected by media, cell-seeding density, and cyclic tensile strain.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 article
Osteogenic differentiation of human mesenchymal stem cells in collagen matrices: Effect of uniaxial cyclic tensile strain on bone morphogenetic protein (BMP-2) mRNA expression
Sumanasinghe, R. D., Bernacki, S. H., & Loboa, E. G. (2006, December). TISSUE ENGINEERING, Vol. 12, pp. 3459–3465.
MeSH headings : Adult; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins / biosynthesis; Bone Morphogenetic Proteins / genetics; Bone and Bones / cytology; Bone and Bones / metabolism; Cell Differentiation / physiology; Cell Survival / physiology; Cells, Cultured; Collagen Type I; Gene Expression Regulation, Developmental / physiology; Humans; Male; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; RNA, Messenger / biosynthesis; Tensile Strength; Transforming Growth Factor beta / biosynthesis; Transforming Growth Factor beta / genetics
TL;DR:
This is the first report of the culture of bone marrow-derived hMSCs in 3D collagen matrices under cyclic strain, and the first demonstration that strain alone can induce osteogenic differentiation without the addition of osteogenic supplements.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
The application of biotextiles in tissue engineering
Research Journal of Textile & Apparel, 9, 80–90.
Source: NC State University Libraries
Added: August 6, 2018
2003 journal article
New trends in Biotextiles: The challenge of tissue engineering
Journal of Textile and Apparel Technology and Management, 3(2), 1–13.
Source: NC State University Libraries
Added: August 6, 2018
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