Works (6)
Updated: July 5th, 2023 15:54
2011 journal article
History Can Matter: Non-Markovian Behavior of Ancestral Lineages
SYSTEMATIC BIOLOGY, 60(3), 276–290.
author keywords: Ancestral lineage; ancestral process; Hill-Robertson effect; population genetics
MeSH headings : Computer Simulation; Evolution, Molecular; Genetic Fitness; Genetic Variation; Markov Chains; Models, Genetic; Polymorphism, Genetic; Selection, Genetic
TL;DR:
This work used the Wright-Fisher model of population genetics to simulate very many generations of mutation, natural selection, and genetic drift to show that the process by which a nonrecombining sequence changes over time can markedly deviate from the Markov assumption that is ubiquitous in molecular phylogenetics.
(via Semantic Scholar)
open access via academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Variation in genome-wide mutation rates within and between human families
Nature Genetics, 43(7), 712–137.
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Antagonism between local dispersal and self-incompatibility systems in a continuous plant population
MOLECULAR ECOLOGY, 18(11), 2327–2336.
author keywords: genetic structure; isolation by distance; local dispersal; neighbourhood size; recombination; self-incompatibility
MeSH headings : Alleles; Computer Simulation; Evolution, Molecular; Gene Flow; Genetic Variation; Genetics, Population; Inbreeding; Models, Genetic; Plants / genetics; Pollen / genetics
TL;DR:
The results suggest that there is little to no difference between the effects of gametophytic and sporophytic self‐incompatibility systems (GSI and SSI) on unlinked loci, and both GSI andSSI affect un linked loci in a manner similar to obligate outcrossing without mating types.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Problems and Solutions for Estimating Indel Rates and Length Distributions
MOLECULAR BIOLOGY AND EVOLUTION, 26(2), 473–480.
MeSH headings : Algorithms; Animals; Humans; INDEL Mutation; Markov Chains; Models, Genetic
TL;DR:
An expectation-maximization algorithm built on a pair hidden Markov model that is able to properly handle indels in neutrally evolving DNA sequences is presented and it is found that a zeta power-law model of indel lengths provides a much better fit than the traditional geometric model and that indel processes are conserved between the authors' taxa.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Ngila: global pairwise alignments with logarithmic and affine gap costs
BIOINFORMATICS, 23(11), 1427–1428.
MeSH headings : Algorithms; Base Sequence; DNA Transposable Elements / genetics; Data Interpretation, Statistical; Gene Deletion; Molecular Sequence Data; Sequence Alignment / methods; Sequence Analysis, DNA / methods; Software
TL;DR:
UNLABELLED Ngila is an application that will find the best alignment of a pair of sequences using log-affine gap costs, which are the most biologically realistic gap costs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Logarithmic gap costs decrease alignment accuracy
BMC Bioinformatics, 7.
Source: NC State University Libraries
Added: August 6, 2018
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