2000 journal article

The ferritin iron entry and exit problem

INORGANICA CHIMICA ACTA, 297(1-2), 242–251.

By: E. Theil*, H. Takagi n, G. Small n, L. He n, A. Tipton & D. Danger n

author keywords: ferritin; iron biominerals; ferroxidation; iron/dioxygen catalysis
TL;DR: The entry and exit of Fe(II) ions in ferritin are endpoints in the process which concentrates iron as a solid (hydrated ferric oxide) to be used by living cells, suggesting a regulation-sensitive biological signal for iron exit. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Rapid and parallel formation of Fe3+ multimers, including a trimer, during H-type subunit ferritin mineralization

BIOCHEMISTRY, 36(25), 7917–7927.

MeSH headings : Animals; Anura; Biopolymers; Electron Spin Resonance Spectroscopy; Ferric Compounds / chemistry; Ferritins / chemistry; Minerals / chemistry; Oxidation-Reduction; Recombinant Proteins / chemistry; Spectroscopy, Mossbauer
TL;DR: The subsequent decay of these multiple Fe3-oxy species to the superparamagnetic mineral suggests that Fe3+ species in different environments may be translocated as intact units from the protein shell into the ferritin cavity where the conversion to a solid mineral occurs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1997 journal article

The influence of conserved tyrosine 30 and tissue-dependent differences in sequence on ferritin function: use of blue and purple Fe(III) species as reporters of ferroxidation

Journal of Biological Inorganic Chemistry, 2(5), 652–661.

By: J. Fetter n, J. Cohen*, D. Danger n, L. Sanders* & E. Theil n

TL;DR: The impact of Y30F on rates of formation of Fe(III)-protein complexes in ferritin, combined with Mössbauer spectroscopic studies, indicate that at least one of the pathways for Fe oxidation/transfer in Ferritin is through the center of the four-helix bundle and is influenced by structural features dependent on tyrosine 30. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

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