Adrian T. O'Neill

Works (4)

Updated: July 5th, 2023 15:55

2009 article

Microfabricated curtains for controlled cell seeding in high throughput microfluidic systems

O'Neill, A. T., Monteiro-Riviere, N. A., & Walker, G. M. (2009, January 1). Lab on a Chip, Vol. 9, pp. 1756–1762.

By: A. O'Neill n, N. Monteiro-Riviere n  & G. Walker n

Contributors: . Adrian T. O'Neill n, N. Monteiro-Riviere n  & G. Walker n

MeSH headings : Cell Culture Techniques / instrumentation; Cell Movement; Cell Proliferation; Cell Survival / drug effects; Collagen / metabolism; Cytotoxins / toxicity; Dimethylpolysiloxanes; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Microfluidic Analytical Techniques / instrumentation; Nylons; Skin / cytology; Time Factors
topics (OpenAlex): 3D Printing in Biomedical Research; Microfluidic and Capillary Electrophoresis Applications; Microfluidic and Bio-sensing Technologies
TL;DR: Curtain use permitted high initial cell seeding densities and increased the amount of time cells can be cultured compared to multi-well plates and showed that cells exposed to 6% ethanol or less grew in population size, 8% ethanol exposure stunted growth, and higher concentrations led to population loss. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 article

Characterization of microfluidic human epidermal keratinocyte culture

O’Neill, A. T., Monteiro-Riviere, N. A., & Walker, G. M. (2008, March 1). Cytotechnology, Vol. 56, pp. 197–207.

By: A. O’Neill n, N. Monteiro-Riviere n  & G. Walker n

Contributors: . Adrian T. O'Neill n, N. Monteiro-Riviere n  & G. Walker n

author keywords: cytotoxicity; high-throughput; keratinocyte; microfluidic; PDMS; toxicology
topics (OpenAlex): 3D Printing in Biomedical Research; Cellular Mechanics and Interactions; Animal testing and alternatives
TL;DR: Human epidermal keratinocytes were shown to maintain 93.0%–99.6% viability at 72 h under medium perfusion ranging from 0.025–0.4 μl min−1, a level not possible in 96 well plates. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 article

A linear dilution microfluidic device for cytotoxicity assays

Walker, G. M., Monteiro-Riviere, N., Rouse, J., & O'Neill, A. T. (2006, October 19). Lab on a Chip, Vol. 7, pp. 226–232.

By: G. Walker n, N. Monteiro-Riviere n , J. Rouse n & A. O'Neill n

Contributors: G. Walker n, N. Monteiro-Riviere n , J. Rouse n & . Adrian T. O'Neill n

MeSH headings : Cells, Cultured; Combinatorial Chemistry Techniques; Diffusion; Drug Evaluation, Preclinical / instrumentation; Drug Evaluation, Preclinical / methods; Electrochemistry / methods; Equipment Design; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Microchemistry; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Microfluidics; Models, Statistical; Models, Theoretical
topics (OpenAlex): Microfluidic and Capillary Electrophoresis Applications; 3D Printing in Biomedical Research; Microfluidic and Bio-sensing Technologies
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 chapter

A serial dilution microfluidic device for cytotoxicity assays

In 28th annual International Conference of the IEEE Engineering in Medicine and Biology Society (pp. 2836–2839). Piscataway, NJ: IEEE.

By: A. O'Neill, N. Monteiro-Riviere  & G. Walker

Source: NC State University Libraries
Added: August 6, 2018

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