Works (4)
Updated: July 5th, 2023 15:55
2009 journal article
Microfabricated curtains for controlled cell seeding in high throughput microfluidic systems
LAB ON A CHIP, 9(12), 1756–1762.
Contributors: . Adrian T. O'Neill*, N. Monteiro-Riviere n & G. Walker*
MeSH headings : Cell Culture Techniques / instrumentation; Cell Movement; Cell Proliferation; Cell Survival / drug effects; Collagen / metabolism; Cytotoxins / toxicity; Dimethylpolysiloxanes; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Microfluidic Analytical Techniques / instrumentation; Nylons; Skin / cytology; Time Factors
TL;DR:
Curtain use permitted high initial cell seeding densities and increased the amount of time cells can be cultured compared to multi-well plates and showed that cells exposed to 6% ethanol or less grew in population size, 8% ethanol exposure stunted growth, and higher concentrations led to population loss.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 journal article
Characterization of microfluidic human epidermal keratinocyte culture
CYTOTECHNOLOGY, 56(3), 197–207.
Contributors: . Adrian T. O'Neill*, N. Monteiro-Riviere* & G. Walker*
author keywords: cytotoxicity; high-throughput; keratinocyte; microfluidic; PDMS; toxicology
TL;DR:
Human epidermal keratinocytes were shown to maintain 93.0%–99.6% viability at 72 h under medium perfusion ranging from 0.025–0.4 μl min−1, a level not possible in 96 well plates.
(via Semantic Scholar)
open access via europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 journal article
A linear dilution microfluidic device for cytotoxicity assays
LAB ON A CHIP, 7(2), 226–232.
Contributors: G. Walker*, N. Monteiro-Riviere n , J. Rouse n & . Adrian T. O'Neill*
MeSH headings : Cells, Cultured; Combinatorial Chemistry Techniques; Diffusion; Drug Evaluation, Preclinical / instrumentation; Drug Evaluation, Preclinical / methods; Electrochemistry / methods; Equipment Design; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Microchemistry; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Microfluidics; Models, Statistical; Models, Theoretical
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 chapter
A serial dilution microfluidic device for cytotoxicity assays
In 28th annual International Conference of the IEEE Engineering in Medicine and Biology Society (pp. 2836–2839). Piscataway, NJ: IEEE.
Source: NC State University Libraries
Added: August 6, 2018
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