@article{georgianna_fedorova_burroughs_dolezal_bok_horowitz-brown_woloshuk_yu_keller_payne_2010, title={Beyond aflatoxin: four distinct expression patterns and functional roles associated with Aspergillus flavus secondary metabolism gene clusters}, volume={11}, ISSN={["1364-3703"]}, DOI={10.1111/J.1364-3703.2009.00594.X}, abstractNote={Species of Aspergillus produce a diverse array of secondary metabolites, and recent genomic analysis has predicted that these species have the capacity to synthesize many more compounds. It has been possible to infer the presence of 55 gene clusters associated with secondary metabolism in Aspergillus flavus; however, only three metabolic pathways-aflatoxin, cyclopiazonic acid (CPA) and aflatrem-have been assigned to these clusters. To gain an insight into the regulation of and to infer the ecological significance of the 55 secondary metabolite gene clusters predicted in A. flavus, we examined their expression over 28 diverse conditions. Variables included culture medium and temperature, fungal development, colonization of developing maize seeds and misexpression of laeA, a global regulator of secondary metabolism. Hierarchical clustering analysis of expression profiles allowed us to categorize the gene clusters into four distinct clades. Gene clusters for the production of aflatoxins, CPA and seven other unknown compound(s) were identified as belonging to one clade. To further explore the relationships found by gene expression analysis, aflatoxin and CPA production were quantified under five different cell culture environments known to be conducive or nonconducive for aflatoxin biosynthesis and during the colonization of developing maize seeds. Results from these studies showed that secondary metabolism gene clusters have distinctive gene expression profiles. Aflatoxin and CPA were found to have unique regulation, but are sufficiently similar that they would be expected to co-occur in substrates colonized with A. flavus.}, number={2}, journal={MOLECULAR PLANT PATHOLOGY}, author={Georgianna, D. Ryan and Fedorova, Natalie D. and Burroughs, James L. and Dolezal, Andrea L. and Bok, Jin Woo and Horowitz-Brown, Sigal and Woloshuk, Charles P. and Yu, Jiujiang and Keller, Nancy P. and Payne, Gary A.}, year={2010}, month={Mar}, pages={213–226} } @misc{pourdeyhimi_fedorova_sharp_2008, title={Lightweight high-tensile, high-tear strength bicomponent nonwoven fabrics}, volume={7,438,777}, number={2008 Oct. 21}, author={Pourdeyhimi, B. and Fedorova, N. V. and Sharp, S. R.}, year={2008} } @article{fedorova_pourdeyhimi_2007, title={High strength nylon micro- and nanofiber based nonwovens via spunbonding}, volume={104}, ISSN={["0021-8995"]}, DOI={10.1002/app.25939}, abstractNote={In this study we explore the feasibility of using of islands-in-the-sea (I/S) fibers in the spunbond process to produce relatively high strength micro- and nanofiber webs. The relationships between the number of islands, percent polymer composition, and the fiber and fabric properties are reported. Nylon 6 (N6) and poly (lactic) acid (PLA) were used as the islands and sea polymers, respectively. Micro- and nanofibers were obtained by dissolving PLA polymer from the final spunbond nonwovens. The fibers with 25% N6 showed a decrease in fiber diameter from 1.3 to 0.36 μm (micron) when the number of islands was increased from 36 to 360. The diameter of fibers with 75% N6 showed a decline from 2.3 to 0.5 μm for the same range. Hydroentangling was found to be the preferred method of bonding of the I/S structures; the bonded structures were able to withstand postprocessing steps required for dissolving of the sea from the resulting nonwovens. Hydroentanged micro- and nanofiber based nonwovens demonstrated high tensile and tear properties, which were insensitive to the N6 fiber size and its mechanical properties. Bonding efficiency and web uniformity were found to be dominant factors influencing the fabric performance. Overall, our study demonstrated that the I/S configuration is a promising technique for high speed and high throughput production of strong and light weight nonwovens comprised of micro- and nanofibers. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007}, number={5}, journal={JOURNAL OF APPLIED POLYMER SCIENCE}, author={Fedorova, Nataliya and Pourdeyhimi, Behnam}, year={2007}, month={Jun}, pages={3434–3442} } @article{fedorova_verenich_pourdeyhimi_2007, title={Strength optimization of thermally bonded spunbond nonwovens}, volume={2}, number={1}, journal={Journal of Engineered Fibers and Fabrics}, author={Fedorova, N. and Verenich, S. and Pourdeyhimi, B.}, year={2007}, pages={38–48} }