Mukund K. Patel

Works (3)

Updated: July 9th, 2023 19:05

2009 article

Analysis of neuronal proliferation, migration and differentiation in the postnatal brain using equine infectious anemia virus-based lentiviral vectors

Jacquet, B. V., Patel, M., Iyengar, M., Liang, H., Therit, B., Salinas-Mondragon, R., … Ghashghaei, H. T. (2009, May 28). Gene Therapy.

By: B. Jacquet n, M. Patel*, M. Iyengar n, H. Liang n, B. Therit n, R. Salinas-Mondragon n, C. Lai *, J. Olsen*, E. Anton*, H. Ghashghaei n

author keywords: adult neural stem cells; adult neurogenesis; lentivirus; EIAV; olfactory bulb; neuronal migration
MeSH headings : Adult Stem Cells / physiology; Animals; Brain / cytology; Brain / physiology; Cell Differentiation; Cell Movement; Cell Proliferation; Defective Viruses; Gene Transfer Techniques; Genetic Vectors; Infectious Anemia Virus, Equine / genetics; Mice; Neural Stem Cells / physiology; Neurogenesis; Neurons / physiology; Olfactory Bulb / cytology; Stem Cell Niche / genetics; Transduction, Genetic
topics (OpenAlex): Neurogenesis and neuroplasticity mechanisms; Virus-based gene therapy research; RNA Interference and Gene Delivery
TL;DR: It is shown that a replication-incompetent Equine Infectious Anemia Virus (EIAV) is highly suitable for stable and persistent gene transfer to adult neural stem cells and ishighly suitable for discovery and assessment of mechanisms that regulate proliferation, migration and differentiation in the postnatal brain. (via Semantic Scholar)
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Added: August 6, 2018

2008 article

The Drosophila Gap Gene giant Has an Anterior Segment Identity Function Mediated Through disconnected and teashirt

Sanders, L. R., Patel, M., & Mahaffey, J. W. (2008, May 1). Genetics.

By: L. Sanders n, M. Patel* & J. Mahaffey n

MeSH headings : Animals; Body Patterning / genetics; DNA Primers / genetics; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / embryology; Gene Expression Regulation, Developmental / genetics; Microscopy, Confocal; Mutation / genetics; Repressor Proteins / genetics; Repressor Proteins / metabolism; Transcription Factors / metabolism
topics (OpenAlex): Developmental Biology and Gene Regulation; Plant Molecular Biology Research; Genomics and Chromatin Dynamics
TL;DR: The regulatory effects of gap genes on the spatial expression of disco, disco-r, and tsh during Drosophila embryogenesis are reported, shedding new light on how mutations in giant (gt) affect patterning within the anterior gt domain, demonstrating homeotic function in this domain. (via Semantic Scholar)
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Added: August 6, 2018

2007 article

The appendage role of insect disco genes and possible implications on the evolution of the maggot larval form

Patel, M., Farzana, L., Robertson, L. K., Hutchinson, J., Grubbs, N., Shepherd, M. N., & Mahaffey, J. W. (2007, June 28). Developmental Biology.

By: M. Patel n, L. Farzana n, L. Robertson n, J. Hutchinson n, N. Grubbs n, M. Shepherd n, J. Mahaffey n

author keywords: drosophila; segment identity; zinc finger; appendage; limb; pattern formation
MeSH headings : Animals; Biological Evolution; Body Patterning; DNA-Binding Proteins / metabolism; Drosophila / embryology; Drosophila / growth & development; Drosophila / metabolism; Drosophila Proteins / metabolism; Head / embryology; Head / growth & development; Larva / growth & development; Larva / metabolism; Transcription Factors / metabolism; Tribolium / embryology; Tribolium / growth & development; Tribolium / metabolism
topics (OpenAlex): Developmental Biology and Gene Regulation; Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
TL;DR: It is proposed that the disco genes always function as appendage factors, but their appendage nature is masked during Drosophila embryogenesis due to the reduction of limb fields in the maggot style Drosophile larva. (via Semantic Scholar)
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Added: August 6, 2018

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