Works (4)
Updated: July 5th, 2023 15:51
2009 journal article
Dermal Permeation of Biocides and Aromatic Chemicals in Three Generic Formulations of Metalworking Fluids
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 72(13), 832–841.
MeSH headings : Animals; Complex Mixtures / chemistry; Disinfectants / chemistry; Disinfectants / pharmacokinetics; Hydrocarbons, Aromatic / chemistry; Hydrocarbons, Aromatic / pharmacokinetics; Metallurgy; Occupational Exposure; Permeability; Skin Absorption / drug effects; Swine
TL;DR:
Data from this study show that permeation of chemicals is higher in a generic synthetic MWF when compared to a soluble oil MWF, which indicates that a solubleOil MWF may be safer than a syntheticMWF in regard to dermal permeations of chemicals to allow for an increased potential of systemic toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Selection of Appropriate Training Set of Chemicals for Modeling Dermal Permeability Using Uniform Coverage Design
QSAR & COMBINATORIAL SCIENCE, 28(11-12), 1478–1486.
author keywords: Skin absorption; LSER; Diverse chemical selection; QSAR; Modeling; Medicinal chemistry; Toxicology
TL;DR:
Graphical plot of the principal components demonstrated that currently used training set of chemicals have narrow representation of parent dataset whereas the selected training set have appropriate representation in terms of chemical space.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2008 article
A solvatochromatic approach to quantifying formulation effects on dermal permeability
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, Vol. 19, pp. 615–630.
author keywords: mixtures; skin; membrane-coated fiber; solvation energy
MeSH headings : Animals; Ethanol / metabolism; Models, Theoretical; Permeability / drug effects; Phenol / metabolism; Skin Physiological Phenomena; Solvents / metabolism; Swine; Toxicology / methods; Water / metabolism
TL;DR:
This research demonstrated that formulation-specific strength coefficients predicted changes in the dermal permeability of phenolic compounds when formulated with commercial metal-working fluid formulations or 50% ethanol and that these effects can be modeled within the context of a linear solvation energy relationship (LSER).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Predicting dermal permeability of biocides in commercial cutting fluids using a LSER approach
Toxicology Letters, 175(1-3), 34–43.
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
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