Works (6)
Updated: July 5th, 2023 15:54
2012 journal article
Dietary Long-Chain PUFA Enhance Acute Repair of Ischemia-Injured Intestine of Suckling Pigs
The Journal of Nutrition, 142(7), 1266–1271.
Contributors: S. Jacobi n, A. Moeser n, n, R. Harrell n, A. Blikslager n & J. Odle n
MeSH headings : Animals; Constriction; Diet; Dietary Fats / pharmacology; Dietary Supplements; Eicosapentaenoic Acid / pharmacology; Electric Impedance; Ileal Diseases / drug therapy; Ileal Diseases / pathology; Ileal Diseases / physiopathology; Ileum / drug effects; Ileum / pathology; Ileum / physiopathology; Intestinal Mucosa / drug effects; Intestinal Mucosa / pathology; Intestinal Mucosa / physiopathology; Inulin / blood; Ischemia / drug therapy; Ischemia / pathology; Ischemia / physiopathology; Mannitol / blood; Mesentery / blood supply; Swine; Wound Healing / drug effects
TL;DR:
It is demonstrated that feeding elevated levels of long-chain PUFA enhances acute recovery of ischemia-injured porcine ileum, and a histological evaluation of ischemic ilea from piglets fed the 5% ARA showed reduced histological lesions after ischemIA compared with the other dietary groups.
(via Semantic Scholar)
open access via jn.nutrition.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Dietary Arachidonate Differentially Alters Desaturase-Elongase Pathway Flux and Gene Expression in Liver and Intestine of Suckling Pigs
The Journal of Nutrition, 141(4), 548–553.
Contributors: S. Jacobi n, X. Lin n, n, H. Hess n, R. Harrell n & J. Odle n
MeSH headings : Acetyltransferases / genetics; Acetyltransferases / metabolism; Animals; Animals, Suckling; Arachidonic Acid / administration & dosage; Delta-5 Fatty Acid Desaturase; Fatty Acid Desaturases / genetics; Fatty Acid Desaturases / metabolism; Fatty Acid Elongases; Fatty Acids / metabolism; Intestinal Mucosa / metabolism; Linoleoyl-CoA Desaturase / genetics; Linoleoyl-CoA Desaturase / metabolism; Liver / metabolism; Organ Specificity; Protein Transport; RNA, Messenger / analysis; Swine
TL;DR:
D dietary ARA regulated the desaturase-elongase pathway in a tissue-specific manner in liver and intestine, and had modest effects on (n-6) fatty acid flux, and intestinal FADS2 activity and mRNA increased.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs
The Journal of Nutritional Biochemistry, 22(11), 1047–1054.
Contributors: X. Lin n, J. Bo n, S. Oliver n, n, S. Jacobi n, W. Oliver n, R. Harrell n, J. Odle n
MeSH headings : Acetyltransferases / metabolism; Animals; Animals, Newborn; Arachidonic Acid / metabolism; Brain / metabolism; Dietary Fats / administration & dosage; Fatty Acid Desaturases / metabolism; Fatty Acid Elongases; Fatty Acids, Unsaturated / metabolism; Linoleic Acid / metabolism; Linoleic Acids, Conjugated / pharmacology; Liver / metabolism; Swine
TL;DR:
Overall, the data show that dietary CLA shifted the distribution of the synthetic products of [U-(13)C]LA between elongation and desaturation in liver and decreased the total synthetic products in brain by inhibiting LA elongation to C20:2n-6.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: NC State University Libraries, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2008 journal article
Arginine Activates Intestinal p70S6k and Protein Synthesis in Piglet Rotavirus Enteritis
The Journal of Nutrition, 138(1), 24–29.
MeSH headings : Animals; Arginine / pharmacology; Dietary Supplements; Enteritis / blood; Enteritis / metabolism; Enzyme Activation / drug effects; Enzyme Inhibitors / pharmacology; Immunohistochemistry; Intestinal Mucosa / enzymology; Intestinal Mucosa / virology; Jejunum / pathology; Protein Biosynthesis / drug effects; Ribosomal Protein S6 Kinases, 70-kDa / metabolism; Rotavirus Infections / enzymology; Rotavirus Infections / metabolism; Sirolimus / pharmacology; Swine / metabolism; Swine / virology
TL;DR:
It is concluded that, early in rotavirus enteritis, Arg has no impact on diarrhea but augments intestinal protein synthesis in part by p70(S6k) stimulation, while improving intestinal permeability via a mammalian target of rapamycin/p70( S6k)-independent mechanism.
(via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2008 journal article
Enrichment of Intestinal Mucosal Phospholipids with Arachidonic and Eicosapentaenoic Acids Fed to Suckling Piglets Is Dose and Time Dependent
The Journal of Nutrition, 138(11), 2164–2171.
Contributors: H. Hess n, n, X. Lin n, S. Jacobi n, R. Harrell n, A. Blikslager n , J. Odle n
MeSH headings : Animals; Arachidonic Acid / administration & dosage; Arachidonic Acid / pharmacology; Diet; Dose-Response Relationship, Drug; Drug Administration Schedule; Eicosapentaenoic Acid / administration & dosage; Eicosapentaenoic Acid / pharmacology; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Lactase / metabolism; Swine
TL;DR:
D doses demonstrate a dose-dependent response of intestinal mucosal phospholipid ARA concentration to dietary ARA with nearly full enrichment attained within 8 d of feeding formula containing ARA and that supra-physiologic supplementation of ARA is not detrimental to growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
Effect of animal plasma proteins on intestinal damage and recovery of neonatal pigs infected with rotavirus
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 18(12), 778–784.
Contributors: n, R. Harrell n, H. Moon n, O. Phillips n, E. Weaver *, J. Campbell *, J. Arthington *, J. Odle n
author keywords: rotavirus; piglet; plasma proteins; intestinal health
MeSH headings : Analysis of Variance; Animal Feed; Animals; Animals, Newborn; Blood Proteins / therapeutic use; Colostrum / physiology; Diarrhea / prevention & control; Diarrhea / virology; Dietary Proteins / therapeutic use; Disease Models, Animal; Rotavirus Infections / physiopathology; Rotavirus Infections / prevention & control; Soybean Proteins / therapeutic use; Swine
TL;DR:
Findings from this study indicate the potential for using plasma proteins to improve the health of diarrheic neonates by reducing acute rotavirus intestinal damage or improved recovery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
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