Brenda J. Grubb

Works (1)

Updated: July 5th, 2023 15:54

2008 journal article

Salinity regulates claudin mRNA and protein expression in the teleost gill

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 294(3), R1004–R1014.

By: C. Tipsmark n, D. Baltzegar n, O. Ozden*, B. Grubb n & R. Borski n

author keywords: osmoregulation; tight junction; tilapia; epithelia
MeSH headings : Amino Acid Sequence; Animals; Blotting, Western; Body Water / metabolism; Claudin-4; Cloning, Molecular; DNA, Complementary / biosynthesis; DNA, Complementary / genetics; Fresh Water; Gills / metabolism; Immunohistochemistry; Membrane Proteins / biosynthesis; Molecular Sequence Data; Muscle, Skeletal / metabolism; Osmolar Concentration; RNA, Messenger / biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Salinity; Seawater; Sodium-Potassium-Chloride Symporters / biosynthesis; Sodium-Potassium-Exchanging ATPase / biosynthesis; Tilapia / metabolism
TL;DR: These studies are the first to detect putative claudin proteins in teleosts and show their localization and regulation with salinity in gill epithelium and indicate that claudins may be important in permeability changes associated with salinity acclimation and possibly the formation of deeper tight junctions in FW gill. (via Semantic Scholar)
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