Susan T. Harbison

Works (8)

Updated: July 5th, 2023 15:53

2019 journal article

Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster

BEHAVIOR GENETICS, 49(1), 60–82.

By: S. Harbison n, S. Kumar *, W. Huang n, L. McCoy n, K. Smith* & T. Mackay n

author keywords: Drosophila melanogaster; Circadian rhythms; Genome-wide association; Period; Rhythmicity index
MeSH headings : Animals; Chromosome Mapping / methods; Circadian Rhythm / genetics; Drosophila Proteins / metabolism; Drosophila Proteins / physiology; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epistasis, Genetic / genetics; Genetic Variation / genetics; Genome-Wide Association Study / methods; Genotype; Mutation / genetics; Phenotype; Sex Characteristics
TL;DR: The observed differences among transcripts for nine genes predicted to interact among themselves and canonical clock genes in the long period line and a control reveal that complex genetic interactions influence high levels of variation in circadian phenotypes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 28, 2019

2013 journal article

Genome-wide association study of sleep in Drosophila melanogaster

BMC Genomics, 14.

By: S. Harbison, L. McCoy & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

A conserved role for syndecan family members in the regulation of whole-body energy metabolism

PLoS One, 5(6).

By: M. De Luca, Y. Klimentidis, K. Casazza, M. Chambers, R. Cho, S. Harbison, P. Jumbo-Lucioni, S. Zhang, J. Leips, J. Fernandez

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep

NATURE GENETICS, 41(3), 371–375.

By: S. Harbison n, M. Carbone n, J. Ayroles n, E. Stone  n, R. Lyman n & T. Mackay n

MeSH headings : Animals; Animals, Genetically Modified; Animals, Inbred Strains; Drosophila / genetics; Drosophila Proteins / genetics; Female; Gene Expression Regulation / physiology; Gene Regulatory Networks / physiology; Genes, Insect; Genetic Variation / physiology; Genome, Insect; Genome-Wide Association Study / veterinary; Male; Models, Biological; Molecular Sequence Data; Polymorphism, Genetic; Sleep / genetics
TL;DR: It is independently confirmed that molecular polymorphisms in Catsup (Catecholamines up) are associated with variation in sleep and that P-element mutations in four candidate genes affect sleep and gene expression and co-regulated gene expression using P- element mutants are confirmed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Energy stores are not altered by long-term partial sleep deprivation in Drosophila melanogaster

PLoS One, 4(7).

By: S. Harbison & A. Sehgal

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Quantitative genetic analysis of sleep in Drosophila melanogaster

GENETICS, 178(4), 2341–2360.

By: S. Harbison* & A. Sehgal*

MeSH headings : Alleles; Analysis of Variance; Animals; Drosophila melanogaster / genetics; Energy Metabolism / genetics; Female; Gene Expression Regulation; Male; Mutagenesis, Insertional; Phenotype; Quantitative Trait, Heritable; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sex Characteristics; Sleep / genetics; Time Factors; Wakefulness / genetics
TL;DR: Mutational genetic correlations among sleep parameters revealed that the genetic basis of the transition between sleep and waking states in males and females may be different, suggesting that sleep may serve a number of different functions rather than a single purpose. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

journal article

Spontaneous mutations and the origin and maintenance of quantitative genetic variation

Huang, W., Lyman, R. F., Lyman, R. A., Carbone, M. A., Harbison, S. T., Magwire, M. M., & Mackay, T. F. C. Elife, 5.

By: W. Huang, R. Lyman, R. Lyman, M. Carbone, S. Harbison, M. Magwire, T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

review

Understanding the neurogenetics of sleep: Progress from Drosophila

Harbison, S. T., Mackay, T. F. C., & Anholt, R. R. H. [Review of ]. Trends in Genetics, 25(6), 262–269.

By: S. Harbison, T. Mackay & R. Anholt

Source: NC State University Libraries
Added: August 6, 2018

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