2020 journal article

Multi-layer dressing made of laminated electrospun nanowebs and cellulose-based adhesive for comprehensive wound care

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 162, 629–644.

By: A. Nada*, E. Ali*, A. Soliman*, J. Shen n, N. Abou-Zeid* & S. Hudson n

author keywords: Multi-layer wound dressing; Graft copolymerization; Encapsulation; Electrospinning
MeSH headings : Animals; Bandages; Cell Line; Cellulose / chemistry; Cellulose / pharmacology; Fibroblasts / metabolism; Fibroblasts / pathology; Gentamicins / chemistry; Gentamicins / pharmacology; Humans; Male; Materials Testing; Nanofibers / chemistry; Rats; Tissue Adhesives / chemistry; Tissue Adhesives / pharmacology; Wounds and Injuries / metabolism; Wounds and Injuries / pathology; Wounds and Injuries / therapy
TL;DR: Biocompatibility test showed insignificant adverse effects of the fabricated layers on fibroblast cells, and Histopathological findings corroborated the intactness of the epidermis layer of the treated samples. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: November 2, 2020

2020 journal article

Synthesis of chitosan iodoacetamides via carbodiimide coupling reaction: Effect of degree of substitution on the hemostatic properties

CARBOHYDRATE POLYMERS, 229.

By: J. Shen n, A. Nada n, N. Abou-Zeid* & S. Hudson n

author keywords: Chitosan iodoacetamide; Hemorrhages; Topical hemostatic dressings; Carbohydrates
MeSH headings : Animals; Biocompatible Materials / chemical synthesis; Biocompatible Materials / chemistry; Biocompatible Materials / pharmacology; Blood Sedimentation / drug effects; Carbodiimides / chemistry; Cell Survival / drug effects; Chitosan / chemistry; Erythrocytes / cytology; Erythrocytes / metabolism; Humans; Hydrogen-Ion Concentration; Iodoacetamide / chemical synthesis; Iodoacetamide / chemistry; Mice
TL;DR: The reaction was confirmed by FT-IR, 1H and 13C NMR, elemental analysis, iodine content analysis, and SEM-EDS, and the biocompatibility of chitosan iodoacetamide slightly declined with increasing the iodide content up to DS 21.5 owing to its affinity to SH groups of cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 6, 2020

2019 journal article

Fabrication and bioevaluation of a medicated electrospun mat based on azido-cellulose acetate via click chemistry

CELLULOSE, 26(18), 9721–9736.

By: A. Nada*, F. Abdellatif*, A. Soliman*, J. Shen n, S. Hudson n & N. Abou-Zeid*

author keywords: Electrospun fiber; Click-scaffold; Azidation; Controlled release; Wound healing; Topical applications
TL;DR: In a rat model, sodium diclofenac and capsaicin-loaded electrospun mats of Azido-CA showed superior closure rates over the untreated rats and those treated with a commercial cream, and showed an acceptable cell viability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: December 2, 2019

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