Alexandra Briner Crawley
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Works (12)
Updated: July 6th, 2023 21:21
2019 journal article
Comparative genomics and evolution of trans-activating RNAs in Class 2 CRISPR-Cas systems
RNA BIOLOGY, 16(4), 435–448.
MeSH headings : Bacteroides / genetics; Base Sequence; CRISPR-Cas Systems / genetics; Conserved Sequence / genetics; Evolution, Molecular; Genomics; Nucleic Acid Conformation; RNA, Bacterial / genetics; RNA, Guide, Kinetoplastida / genetics; Repetitive Sequences, Nucleic Acid / genetics; Streptococcus / genetics; Thermodynamics; Trans-Activators / genetics
Sources: Web Of Science, ORCID
Added: May 20, 2019
2018 journal article
CRISPRdisco: An Automated Pipeline for the Discovery and Analysis of CRISPR-Cas Systems
CRISPR JOURNAL, 1(2), 171–181.
www.liebertpub.com (publisher PDF)
Sources: Web Of Science, ORCID
Added: February 25, 2019
2018 journal article
Conserved Genome Organization and Core Transcriptome of the Lactobacillus acidophilus Complex
FRONTIERS IN MICROBIOLOGY, 9.
author keywords: Lactobacillus; core genome; core transcriptome; microbial genetics; chromosome organization
Sources: Web Of Science, ORCID
Added: October 19, 2018
2018 journal article
Deletion-based escape of CRISPR-Cas9 targeting in Lactobacillus gasseri
MICROBIOLOGY-SGM, 164(9), 1098–1111.
author keywords: Lactobacillus; CRISPR; Cas; Cas9; interference; spacer
MeSH headings : CRISPR-Associated Protein 9 / metabolism; Clustered Regularly Interspaced Short Palindromic Repeats; Interspersed Repetitive Sequences; Lactobacillus gasseri / genetics; Mutation; Plasmids; Recombination, Genetic; Sequence Deletion; Transformation, Bacterial
Sources: Web Of Science, ORCID
Added: December 31, 2018
2018 journal article
The Lactobacillus Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation
MSPHERE, 3(3).
Ed(s): C. Ellermeier
author keywords: Lactobacillus; bile acid; bile salt hydrolase; gastrointestinal tract; niche; penicillin V acylase; probiotic; therapeutic
MeSH headings : Adaptation, Biological; Amidohydrolases / genetics; Genetic Variation; Genotype; Lactobacillus / classification; Lactobacillus / enzymology; Lactobacillus / genetics; Penicillin Amidase / genetics; Phylogeny; Sequence Homology
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum
FRONTIERS IN MICROBIOLOGY, 8.
author keywords: CRISPR-Cas systems; genotyping; probiotics; Bifidobacterium longum
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 review
Deciphering and shaping bacterial diversity through CRISPR
[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 31, 101–108.
MeSH headings : Bacteria / genetics; Bacteria / virology; Bacteriophages / genetics; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Genome, Bacterial / genetics; Host-Pathogen Interactions / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems
MOLECULAR CELL, 62(1), 137–147.
MeSH headings : Bacillus / chemistry; Bacillus / metabolism; CRISPR-Associated Proteins / chemistry; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems; Escherichia coli / chemistry; Escherichia coli / metabolism; Francisella / chemistry; Francisella / metabolism; High-Throughput Screening Assays / methods; Protein Structure, Tertiary; Streptococcus thermophilus / chemistry; Streptococcus thermophilus / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera
NATURE COMMUNICATIONS, 6.
MeSH headings : Biotechnology; Genome, Bacterial; Lactobacillus / enzymology; Lactobacillus / genetics; Leuconostoc / genetics; Pediococcus / genetics; Phylogeny; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium
PLOS ONE, 10(7).
Ed(s): C. Riedel
MeSH headings : Bifidobacterium / genetics; CRISPR-Cas Systems / genetics; Chromosomes, Bacterial / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; DNA / genetics; Evolution, Molecular; Genetic Variation / genetics; Genome, Bacterial / genetics; Prophages / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality
MOLECULAR CELL, 56(2), 333–339.
MeSH headings : Bacterial Proteins / chemistry; CRISPR-Associated Protein 9; CRISPR-Associated Proteins / chemistry; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; DNA / chemistry; DNA Cleavage; Endonucleases / chemistry; Genetic Engineering / methods; HEK293 Cells; Humans; Nucleic Acid Conformation; RNA, Guide, Kinetoplastida / chemistry; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / ultrastructure
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Lactobacillus buchneri Genotyping on the Basis of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Locus Diversity
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(3), 994–1001.
MeSH headings : Clustered Regularly Interspaced Short Palindromic Repeats; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Food Microbiology; Genetic Variation; Genotype; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / isolation & purification; Molecular Sequence Data; Molecular Typing / methods; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018
