2020 journal article
Caspases from scleractinian coral show unique regulatory features
JOURNAL OF BIOLOGICAL CHEMISTRY, 295(43), 14578–14591.
2016 journal article
Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(41), E6080–E6088.
2014 journal article
Modifying Caspase-3 Activity by Altering Allosteric Networks
BIOCHEMISTRY, 53(48), 7582–7595.
2014 journal article
Redesigning the procaspase-8 dimer interface for improved dimerization
Protein Science, 23(4), 442–453.
2013 journal article
Lengthening the Intersubunit Linker of Procaspase 3 Leads to Constitutive Activation
BIOCHEMISTRY, 52(36), 6219–6231.
2013 journal article
Slow folding and assembly of a procaspase-3 interface variant
Biochemistry, 52(20), 3415–3427.
2012 journal article
Allosteric modulation of caspase 3 through mutagenesis
BIOSCIENCE REPORTS, 32(4), 401–411.
2011 journal article
A bifunctional allosteric site in the dimer interface of procaspase-3
BIOPHYSICAL CHEMISTRY, 159(1), 100–109.
2011 journal article
Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 508(1), 31–38.
2010 review
The potential for caspases in drug discovery
[Review of ]. Current Opinion in Drug Discovery & Development, 13(5), 568–576.
2009 journal article
A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis
BIOCHEMICAL JOURNAL, 424, 335–345.
2009 journal article
Folding and assembly kinetics of procaspase-3
PROTEIN SCIENCE, 18(12), 2500–2517.
2009 review
Practical approaches to protein folding and assembly: Spectroscopic strategies in thermodynamics and kinetics
[Review of ]. Methods in enzymology: biothermodynamics,vol 455, part a, 455, 1–39.
2008 review
Minimizing frustration by folding in an aqueous environment
[Review of ]. Archives of Biochemistry and Biophysics, 469(1), 118–131.
2008 journal article
Protein folding: Are we there yet?
Archives of Biochemistry and Biophysics, 469(1), 1–3.
2008 review
Targeting cell death in tumors by activating Caspases
[Review of ]. Current Cancer Drug Targets, 8(2), 98–109.
2007 journal article
Rapid folding and unfolding of Apaf-1 CARD
JOURNAL OF MOLECULAR BIOLOGY, 369(1), 290–304.
2006 journal article
Role of loop bundle hydrogen bonds in the maturation and activity of (pro) caspase-3
BIOCHEMISTRY, 45(44), 13249–13263.
2006 journal article
Substitutions of prolines examine their role in kinetic trap formation of the caspase recruitment domain (CARD) of RICK
PROTEIN SCIENCE, 15(3), 395–409.
2005 journal article
Characterization and enzymatic degradation of Sup35NM, a yeast prion-like protein
PROTEIN SCIENCE, 14(9), 2228–2235.
2005 journal article
Novel protein purification system utilizing an N-terminal fusion protein and a caspase-3 cleavable linker
Protein Expression and Purification, 47(1), 311–318.
2005 journal article
Reassembly of active caspase-3 is facilitated by the propeptide
JOURNAL OF BIOLOGICAL CHEMISTRY, 280(48), 39772–39785.
2005 journal article
pH effects on the stability and dimerization of procaspase-3
Protein Science, 14(1), 24–36.
2004 journal article
Evaluation of the DNA Binding Tendencies of the Transition State Regulator AbrB†
Biochemistry, 43(51), 16106–16118.
2004 journal article
Ionic interactions near the loop L4 are important for maintaining the active-site environment and the dimer stability of (pro)caspase 3
Biochemical Journal (London, England : 1984), 384(Dec 15 2004), 515–525.
2004 journal article
Kinetic traps in the folding/unfolding of procaspase-1 CARD domain
PROTEIN SCIENCE, 13(8), 2196–2206.
2003 journal article
An uncleavable procaspase-3 mutant has a lower catalytic efficiency but an active site similar to that of mature caspase-3
BIOCHEMISTRY, 42(42), 12298–12310.
2003 journal article
Equilibrium and kinetic folding of a alpha-helical Greek key protein domain: Caspase recruitment domain (CARD) of RICK
BIOCHEMISTRY, 42(20), 6310–6320.
2003 journal article
Mutations in the procaspase-3 dimer interface affect the activity of the zymogen
BIOCHEMISTRY, 42(42), 12311–12320.
2003 journal article
The C-terminal tail of Arabidopsis 14-3-3 omega functions as an autoinhibitor and may contain a tenth alpha-helix
PLANT JOURNAL, 34(4), 473–484.
2001 journal article
Dimeric procaspase-3 unfolds via a four-state equilibrium process
BIOCHEMISTRY, 40(47), 14236–14242.
2001 journal article
Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer
BIOCHEMISTRY, 40(47), 14224–14235.
2000 journal article
A rapid chromatographic method to separate the subunits of bacterial luciferase in urea-containing buffer
Bioluminescence and Chemiluminescence, Pt. C, 305, 157–164.
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