2022 journal article

Modeling cell protrusion predicts how myosin II and actin turnover affect adhesion-based signaling

BIOPHYSICAL JOURNAL, 121(1), 102–118.

By: A. Chandra n, M. Butler*, J. Bear* & J. Haugh n

MeSH headings : Actin Cytoskeleton / metabolism; Actins / metabolism; Cell Surface Extensions; Myosin Type II / metabolism; Signal Transduction
TL;DR: A positive feedback loop is presented, whereby adhesion-based signaling promotes generation of barbed ends at, and protrusion of, the cell's leading edge, which in turn promotes formation and stabilization of nascent adhesions. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022

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