Works (3)
Updated: July 5th, 2023 15:46
2016 journal article
Enhanced cellular infiltration of human adipose-derived stem cells in allograft menisci using a needle-punch method
Journal of Orthopaedic Surgery and Research, 11.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Cyclic Tensile Strain Enhances Osteogenesis and Angiogenesis in Mesenchymal Stem Cells from Osteoporotic Donors
TISSUE ENGINEERING PART A, 20(1-2), 67–78.
MeSH headings : Aged, 80 and over; Calcium / metabolism; Cell Differentiation; Cell Proliferation; Cell Separation; Female; Gene Expression Regulation; Gene Regulatory Networks; Humans; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / pathology; Neovascularization, Physiologic / genetics; Oligonucleotide Array Sequence Analysis; Osteogenesis / genetics; Osteoporosis, Postmenopausal / genetics; Osteoporosis, Postmenopausal / pathology; Proto-Oncogene Mas; Real-Time Polymerase Chain Reaction; Signal Transduction / genetics; Stress, Mechanical; Tensile Strength; Tissue Donors; White People
TL;DR:
It is demonstrated that hMSC from aged, osteoporotic donors are capable of enhanced osteogenic differentiation in response to 10% cyclic tensile strain with significant increases in the expression of genes associated with enhanced cell proliferation, musculoskeletal development, and angiogenesis.
(via Semantic Scholar)
open access via europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Microarray Analysis of Human Adipose-Derived Stem Cells in Three-Dimensional Collagen Culture: Osteogenesis Inhibits Bone Morphogenic Protein and Wnt Signaling Pathways, and Cyclic Tensile Strain Causes Upregulation of Proinflammatory Cytokine Regulators and Angiogenic Factors
TISSUE ENGINEERING PART A, 17(21-22), 2615–2627.
MeSH headings : Adipose Tissue / cytology; Adult; Angiogenesis Inducing Agents / metabolism; Bone Morphogenetic Proteins / genetics; Bone Morphogenetic Proteins / metabolism; Cells, Cultured; Collagen / metabolism; Cytokines / genetics; Cytokines / metabolism; Humans; Insulin-Like Growth Factor I / genetics; Middle Aged; Oligonucleotide Array Sequence Analysis / methods; Osteogenesis / genetics; Osteogenesis / physiology; Platelet-Derived Growth Factor / genetics; Signal Transduction / genetics; Signal Transduction / physiology; Stem Cells / cytology; Stem Cells / metabolism; Wnt Signaling Pathway / genetics; Wnt Signaling Pathway / physiology
TL;DR:
This first study to investigate the effects of both 3D culture and mechanical load on hASC osteogenic differentiation and response to mechanical stimuli identified specific genes and pathways associated with mechanical response and osteogenic potential of hASC, thus providing significant information toward improved understanding of its use for functional bone tissue engineering applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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