2024 article

Evaluation of Adjuvant Effect of Cytosine-Guanosine-Oligodeoxynucleotide in Meat-Type Chickens Coadministered <i>In Ovo</i> with Herpesvirus of Turkey Vaccine

Boone, A. C., Kulkarni, R. R., Cortes, A. L., Gaghan, C., Mohammed, J., Villalobos, T., … Gimeno, I. M. (2024, February 1). VIRAL IMMUNOLOGY, Vol. 2.

By: A. Boone n, R. Kulkarni n, A. Cortes n, C. Gaghan n, J. Mohammed*, T. Villalobos*, J. Esandi*, I. Gimeno n

author keywords: herpesvirus of turkey; toll-like receptor 21; cellular immunity; immunocompetence; in ovo vaccination; chickens
TL;DR: Adding cytosine-guanosine oligodeoxynucleotides (CpG ODNs) to the HVT vaccine could enhance the adjuvant effect of HVT, and CpG ODN administration in ovo with or without HVT significantly increased frequencies of activated CD4+ and CD8+ T cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 2, 2024

2023 journal article

In ovo HVT vaccination enhances cellular responses at hatch and addition of poly I:C offers minimal adjuvant effects

VACCINE, 41(15), 2514–2523.

By: A. Boone n, R. Kulkarni n, A. Cortes n, T. Villalobos*, J. Esandi* & I. Gimeno n

author keywords: Herpesvirus of turkey; Toll -like receptor 3; Innate and Cellular immunity; Immunocompetence; In ovo vaccination; Chickens
MeSH headings : Animals; Chickens; Poly I-C / pharmacology; Toll-Like Receptor 3; Interleukin-13; CD28 Antigens; Marek Disease; Herpesvirus 1, Meleagrid; Interferon-gamma; Vaccination / veterinary
TL;DR: The cellular mechanisms by which HVT-RD can hasten immunocompetence in one-day-old meat-type chickens are evaluated, and it is determined if HVT adjuvantation with a TLR3 agonist, polyinosinic-polycytidylic acid (poly(I:C)), could enhance vaccine-induced responses and provide dose-sparing effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 8, 2023

2020 journal article

In ovo vaccination with herpesvirus of turkey enhances innate and cellular responses in meat-type chickens: Effect of vaccine dose and strain

VACCINE, 38(31), 4837–4845.

By: A. Boone n, T. Kaser n, A. Cortes n, R. Kulkarni n, B. Abad n, T. Villalobos*, J. Esandi*, F. Perozo*, S. Lemiere*, I. Gimeno n

author keywords: Herpesvirus of turkey; Immunocompetence; In ovo vaccination; Chickens
MeSH headings : Animals; Chick Embryo; Chickens; Herpesvirus 1, Meleagrid; Marek Disease; Meat; Poultry Diseases / prevention & control; Vaccination; Viral Vaccines
TL;DR: It is demonstrated in ovo vaccination with HVT in meat-type chickens can accelerate innate and adaptive immunity and one could optimize such effect by modifying the vaccine dose. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 6, 2020

2010 journal article

Pathology in practice

Journal of the American Veterinary Medical Association, 237(3), 277–279.

By: A. Boone, L. Susta, R. Rech, R. Steffens & E. Howerth

Source: NC State University Libraries
Added: August 6, 2018

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