Alexander Deiters

Transcriptional Inhibition of MicroRNA miR-122 by Small Molecules Reduces Hepatitis C Virus Replication in Liver Cells

Emanuelson, C., Ankenbruck, N., Kumbhare, R., Thomas, M., Connelly, C., Baktash, Y., … Deiters, A. (2022, November 30). JOURNAL OF MEDICINAL CHEMISTRY.

Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling

JOURNAL OF BIOLOGICAL CHEMISTRY, 295(25), 8494–8504.

A concise synthesis of the Lycopodium alkaloid cermizine D

TETRAHEDRON LETTERS, 56(23), 3683–3685.

Conditional Control of Alternative Splicing through Light-Triggered Splice-Switching Oligonucleotides

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137(10), 3656–3662.

Light-cleavable rapamycin dimer as an optical trigger for protein dimerization

CHEMICAL COMMUNICATIONS, 51(26), 5702–5705.

Optically triggered immune response through photocaged oligonucleotides

TETRAHEDRON LETTERS, 56(23), 3639–3642.

Control of Protein Function through Optochemical Translocation

ACS SYNTHETIC BIOLOGY, 3(10), 731–736.

Genetic Encoding of Caged Cysteine and Caged Homocysteine in Bacterial and Mammalian Cells

CHEMBIOCHEM, 15(12), 1793–1799.

Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes

CHEMICAL COMMUNICATIONS, 50(86), 13085–13088.

Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes (vol 50, pg 13085, 2014)

Lee, Y.-J., Kurra, Y., Yang, Y., Torres-Kolbus, J., Deiters, A., & Liu, W. R. (2014, November 11). CHEMICAL COMMUNICATIONS, Vol. 50, pp. 13396–13396.

Intracellular Light-Activation of Riboswitch Activity

ChemBioChem, 15(9), 1346–1351.

MicroRNA Targeting of CoREST Controls Polarization of Migrating Cortical Neurons

CELL REPORTS, 7(4), 1168–1183.

Optochemical Control of Deoxyoligonucleotide Function via a Nucleobase-Caging Approach

[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 47(1), 45–55.

Site-Specific Promoter Caging Enables Optochemical Gene Activation in Cells and Animals

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(19), 7152–7158.

Synthesis of Non-linear Protein Dimers through a Genetically Encoded Thiol-ene Reaction

PLOS ONE, 9(9).

Thiourea-Based Fluorescent Chemosensors for Aqueous Metal Ion Detection and Cellular Imaging

JOURNAL OF ORGANIC CHEMISTRY, 79(13), 6054–6060.

Two Rapid Catalyst-Free Click Reactions for In Vivo Protein Labeling of Genetically Encoded Strained Alkene/Alkyne Functionalities

BIOCONJUGATE CHEMISTRY, 25(9), 1730–1738.

Cellular Delivery and Photochemical Activation of Antisense Agents through a Nucleobase Caging Strategy

ACS CHEMICAL BIOLOGY, 8(10), 2272–2282.

DNA Computation in Mammalian Cells: MicroRNA Logic Operations

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 135(28), 10512–10518.

Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells

Journal of the American Chemical Society, 135(36), 13433–13439.

MicroRNA miR-122 as a therapeutic target for oligonucleotides and small molecules

Current Medicinal Chemistry, 20(29), 3629–3640.

Optochemical control of RNA interference in mammalian cells

NUCLEIC ACIDS RESEARCH, 41(22), 10518–10528.

DNA Computation: A Photochemically Controlled AND Gate

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134(8), 3810–3815.

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

NATURE CHEMISTRY, 4(4), 298–304.

High-Throughput Luciferase Reporter Assay for Small-Molecule Inhibitors of MicroRNA Function

JOURNAL OF BIOMOLECULAR SCREENING, 17(6), 822–828.

Hydrogen Peroxide Induced Activation of Gene Expression in Mammalian Cells using Boronate Estrone Derivatives

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(36), 9066–9070.

Light-controlled synthetic gene circuits

[Review of ]. CURRENT OPINION IN CHEMICAL BIOLOGY, 16(3-4), 292–299.

Photocontrol of Tyrosine Phosphorylation in Mammalian Cells via Genetic Encoding of Photocaged Tyrosine

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134(29), 11912–11915.

Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells

ACS Chemical Biology, 7(7), 1247–1256.

Spatiotemporal control of microRNA function using light-activated antagomirs

MOLECULAR BIOSYSTEMS, 8(11), 2987–2993.

A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos

Development, 139(2), 437–442.

Efficacy of C-N Coupling Reactions with a New Multinuclear Copper Complex Catalyst and Its Dissociation into Mononuclear Species

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2011(22), 4154–4159.

Genetically encoding an aliphatic diazirine for protein photocrosslinking

CHEMICAL SCIENCE, 2(3), 480–483.

Heterotaxin: A TGF-beta Signaling Inhibitor Identified in a Multi-Phenotype Profiling Screen in Xenopus Embryos

CHEMISTRY & BIOLOGY, 18(2), 252–263.

Light Regulation of Protein Dimerization and Kinase Activity in Living Cells Using Photocaged Rapamycin and Engineered FKBP

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(3), 420–423.

Light-Activated Gene Editing with a Photocaged Zinc-Finger Nuclease

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 50(30), 6839–6842.

Light-Activated Kinases Enable Temporal Dissection of Signaling Networks in Living Cells

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(7), 2124–2127.

Photochemical Control of DNA Decoy Function Enables Precise Regulation of Nuclear Factor kappa B Activity

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(33), 13176–13182.

Photochemical control of bacterial signal processing using a light-activated erythromycin

MOLECULAR BIOSYSTEMS, 7(9), 2554–2557.

Stabilization and Photochemical Regulation of Antisense Agents through PEGylation

BIOCONJUGATE CHEMISTRY, 22(10), 2136–2142.

Synthesis of the Pyridine Core of Cyclothiazomycin

ORGANIC LETTERS, 13(16), 4352–4355.

The Human Mitochondrial tRNA(Met): Structure/Function Relationship of a Unique Modification in the Decoding of Unconventional Codons

JOURNAL OF MOLECULAR BIOLOGY, 406(2), 257–274.

Activation and Deactivation of DNAzyme and Antisense Function with Light for the Photochemical Regulation of Gene Expression in Mammalian Cells

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(17), 6183–6193.

Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(42), 14819–14824.

Generating Permissive Site-Specific Unnatural Aminoacyl-tRNA Synthetases

BIOCHEMISTRY, 49(8), 1667–1677.

Genetically encoded photocontrol of protein localization in mammalian cells

Journal of the American Chemical Society, 132(12), 4086-.

Improved Synthesis of the Two-Photon Caging Group 3-Nitro-2-Ethyldibenzofuran and Its Application to a Caged Thymidine Phosphoramidite

ORGANIC LETTERS, 12(5), 916–919.

Photocaged Morpholino Oligomers for the Light-Regulation of Gene Function in Zebrafish and Xenopus Embryos

Journal of the American Chemical Society, 132(44), 15644–15650.

Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro- and Eukaryotic Cells

CHEMBIOCHEM, 11(7), 972–977.

Photocleavable Polyethylene Glycol for the Light-Regulation of Protein Function

BIOCONJUGATE CHEMISTRY, 21(8), 1404–1407.

Principles and Applications of the Photochemical Control of Cellular Processes

CHEMBIOCHEM, 11(1), 47–53.

Recent advances in the photochemical control of protein function

[Review of ]. TRENDS IN BIOTECHNOLOGY, 28(9), 468–475.

Reversible light switching of cell signalling by genetically encoded protein dimerization

Chembiochem, 11(3), 301–303.

Site-Specific Incorporation of Fluorotyrosines into Proteins in Escherichia coli by Photochemical Disguise

BIOCHEMISTRY, 49(8), 1557–1559.

Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(23), 7976–7981.

Small Molecule Modifiers of the microRNA and RNA Interference Pathway

[Review of ]. AAPS JOURNAL, 12(1), 51–60.

Total Synthesis of Cryptoacetalide

JOURNAL OF ORGANIC CHEMISTRY, 75(15), 5355–5358.

Tricyclic Alkaloid Core Structures Assembled by a Cyclotrimerization-Coupled Intramolecular Nucleophilic Substitution Reaction

ORGANIC LETTERS, 12(6), 1288–1291.

A Light-Activated DNA Polymerase

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48(32), 5950–5953.

Development of a Robust and High Throughput Method for Profiling N-Linked Glycans Derived from Plasma Glycoproteins by NanoLC-FTICR Mass Spectrometry

JOURNAL OF PROTEOME RESEARCH, 8(7), 3764–3770.

Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteins via a Pyrrolysyl-tRNA Synthetase/tRNA(CUA) Pair and Click Chemistry

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(25), 8720-+.

Light activation as a method of regulating and studying gene expression

[Review of ]. CURRENT OPINION IN CHEMICAL BIOLOGY, 13(5-6), 678–686.

Light-Activated Cre Recombinase as a Tool for the Spatial and Temporal Control of Gene Function in Mammalian Cells

ACS CHEMICAL BIOLOGY, 4(6), 441–445.

Light-activation of gene function in mammalian cells via ribozymes

Chem. Commun., (5), 568–570.

Open-Vessel Microwave-Mediated [2+2+2]-Cyclotrimerization Reactions

SYNTHESIS-STUTTGART, (22), 3785–3790.

Photochemical Regulation of Restriction Endonuclease Activity

CHEMBIOCHEM, 10(10), 1612–1616.

Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization

Nucleic Acids Research, 37(8).

The effect of microwave irradiation on DNA hybridization

ORGANIC & BIOMOLECULAR CHEMISTRY, 7(12), 2506–2508.

A cyclotrimerization route to cannabinoids

ORGANIC LETTERS, 10(11), 2195–2198.

A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine

CHEMICAL COMMUNICATIONS, (39), 4750–4752.

Gene Silencing in Mammalian Cells with Light-Activated Antisense Agents

ChemBioChem, 9(18), 2937–2940.

Light-activated deoxyguanosine: photochemical regulation of peroxidase activity

MOLECULAR BIOSYSTEMS, 4(6), 508–511.

Light-regulated RNA-small molecule interactions

CHEMBIOCHEM, 9(8), 1225–1228.

Light-triggered polymerase chain reaction

CHEMICAL COMMUNICATIONS, (4), 462–464.

Microwave activation of enzymatic catalysis

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(31), 10048-+.

Microwave-assisted synthesis of unnatural amino acids

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18(20), 5478–5480.

Microwave-mediated Nickel-catalyzed cyclotrimerization reactions: Total synthesis of illudinine

JOURNAL OF ORGANIC CHEMISTRY, 73(1), 342–345.

Phenanthridine synthesis via [2+2+2] cyclotrimerization reactions

ORGANIC & BIOMOLECULAR CHEMISTRY, 6(2), 263–265.

Small-molecule inhibitors of microRNA miR-21 function

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47(39), 7482–7484.

Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNA(Met)

NUCLEIC ACIDS RESEARCH, 36(20), 6548–6557.

Synthesis of Anthracene and Azaanthracene Fluorophores via [2+2+2] Cyclotrimerization Reactions

ORGANIC LETTERS, 10(20), 4661–4664.

A general approach to chemo- and regioselective cyclotrimerization reactions

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(27), 5187–5190.

Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry

JOURNAL OF COMBINATORIAL CHEMISTRY, 9(5), 735–738.

Photochemical DNA activation

ORGANIC LETTERS, 9(10), 1903–1906.

Photochemical activation of protein expression in bacterial cells

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(23), 4290–4292.

Photochemical control of biological processes

ORGANIC & BIOMOLECULAR CHEMISTRY, 5(7), 999–1005.

Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization

JOURNAL OF ORGANIC CHEMISTRY, 72(20), 7801–7804.

A genetically encoded fluorescent amino acid

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(26), 9785–9789.

A genetically encoded photocaged tyrosine

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 45(17), 2728–2731.

A new photocaging group for aromatic N-heterocycles

SYNTHESIS-STUTTGART, (13), 2147–2150.

Conditional transgene and gene targeting methodologies in zebrafish

Zebrafish, 3, 415–429.

General strategy for the syntheses of corynanthe, tacaman, and oxindole alkaloids

[Review of ]. JOURNAL OF ORGANIC CHEMISTRY, 71(17), 6547–6561.

Photochemical hammerhead ribozyme activation

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(10), 2658–2661.

Pyridines via solid-supported [2+2+2] cyclotrimerization

Chemical Communications (Cambridge, England), (12), 1313–1315.

Solid-supported [2+2+2] cyclotrimerizations

CHEMISTRY-A EUROPEAN JOURNAL, 12(21), 5563–5568.

Synthesis of oxygen- and nitrogen-containing heterocycles by ring-closing metathesis

[Review of ]. CHEMICAL REVIEWS, 104(5), 2199–2238.