Ahmad Ud Din

Also known as: Ahmad

https://orcid.org/0000-0001-9879-2023

Gut microbiome, IBD, Probiotics, miRNA, CVD, Atherosclerosis, Mice Model, DSS/TNBS, T2D

Focused Research is microbial consortia and relates them with different diseases and health conditions, which is specifically in line with my current research on colon cancer (colitis), diabetes and atherosclerosis using probiotics in mice models as well as some other related projects on the gut microbiome. Research keywords include Probiotics, Bifidobacterium, Lactobacillus Gut Microbiome, CVD, Diabetes, Colitis, Atherosclerosis, miRNA, Drugs, Antibiotic Resistance, Nutrients, Metabolism, and Metabolites (TMAO, Colibactin, Polyphenols, SCFA, Imidazole Propionate, AHL; AhR/IL-22).

Works (30)

Updated: August 29th, 2023 11:23

2023 journal article

A narrative review: CXC chemokines influence immune surveillance in obesity and obesity-related diseases: Type 2 diabetes and nonalcoholic fatty liver disease

Reviews in Endocrine and Metabolic Disorders.

MeSH headings : Humans; Non-alcoholic Fatty Liver Disease / metabolism; Diabetes Mellitus, Type 2 / metabolism; Chemokines, CXC / metabolism; Obesity / metabolism; Insulin Resistance; Inflammation / metabolism; Liver / metabolism
Source: ORCID
Added: August 5, 2023

2023 journal article

Assessment of the impact of intravenous antibiotics treatment on gut microbiota in patients: Clinical data from pre-and post-cardiac surgery

Frontiers in Cellular and Infection Microbiology, 12.

By: L. Xue*, Y. Ding, Q. Qin, L. Liu, X. Ding, Y. Zhou, K. Liu, R. Singla ...

MeSH headings : Humans; Aged; Gastrointestinal Microbiome; Anti-Bacterial Agents / therapeutic use; Anti-Bacterial Agents / pharmacology; RNA, Ribosomal, 16S / genetics; Vitamin K 2 / pharmacology; Cardiac Surgical Procedures; Feces / microbiology
Source: ORCID
Added: August 6, 2023

2023 journal article

Desulfovibrio desulfuricans aggravates atherosclerosis by enhancing intestinal permeability and endothelial TLR4/NF-KB pathway in Apoe-/- mice

Genes & Diseases, 10.

By: K. Zhang*, X. Qin, J. Qiu*, T. Sun*, K. Qu*, A. Din*, W. Yan*, T. Li* ...

Source: ORCID
Added: August 5, 2023

2023 journal article

Oligosaccharides of Polygonatum Cyrtonema Hua ameliorates dextran sulfate sodium-induced colitis and regulates the gut microbiota

Biomedicine &Amp; Pharmacotherapy, 161, 114562.

By: J. Xu, C. Tang, A. Din*, Y. Lu, X. Ma, T. Zhang, J. Wu, D. Zuoqin, P. Luo, J. Wu

Source: ORCID
Added: August 6, 2023

2023 journal article

Translational informatics for human microbiota: data resources, models and applications

Briefings in Bioinformatics, 24(3).

By: K. Shen*, A. Din*, B. Sinha*, Y. Zhou*, F. Qian* & B. Shen*

Source: ORCID
Added: August 6, 2023

2022 journal article

Emerging Piezo1 signaling in inflammation and atherosclerosis; a potential therapeutic target

International Journal of Biological Sciences.

Source: ORCID
Added: August 5, 2023

2022 journal article

Evaluation of Cardiac Biomarkers and Expression Analysis of IL-1, IL-6, IL-10, IL-17, and IL-25 among COVID-19 Patients from Pakistan

Viruses.

By: R. Ullah*, J. Khan*, N. Basharat*, D. Huo*, A. Din* & G. Wang*

MeSH headings : Humans; COVID-19; SARS-CoV-2; Interleukin-6; Interleukin-10; Interleukin-17 / genetics; Pakistan; Biomarkers; Cytokines; Troponin; Interleukin-1
Source: ORCID
Added: August 5, 2023

2022 journal article

Isolation, characterization, bacteriocin production and biological potential of Bifidobacteria of ruminants

Analytical Biochemistry, 658, 114926.

MeSH headings : Animals; Acrylamides; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / chemistry; Bacteriocins / pharmacology; Bacteriocins / chemistry; Bifidobacterium; Edetic Acid; Escherichia coli; Glucose; Hydrogen-Ion Concentration; Ruminants / microbiology; Sodium Chloride; Sodium Dodecyl Sulfate; Staphylococcus aureus; Urea
Source: ORCID
Added: August 6, 2023

2022 journal article

Metagenomic Analysis of Liquor Starter Culture Revealed Beneficial Microbes’ Presence

Foods.

By: A. Din*, W. Ahmad*, T. Khan*, J. Wang* & J. Wu*

Source: ORCID
Added: August 5, 2023

2022 journal article

Seroprevalence of Anti-tTg-IgA among Symptomized Celiac Disease Patients and Their Correlation with Rotavirus Infection

BioMed Research International.

By: A. Sadiq, J. Khan*, I. Ullah*, N. Basharat*, S. Ali*, A. Din*, I. Ali*, A. Farid* ...

Ed(s): H. Pan

MeSH headings : Adolescent; Autoantibodies; Celiac Disease / epidemiology; Child; Child, Preschool; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Glutens; Humans; Immunoglobulin A / analysis; Rotavirus Infections / epidemiology; Seroepidemiologic Studies; Transglutaminases
Source: ORCID
Added: August 5, 2023

2021 journal article

Analyzing differentially expressed genes and pathways of Bex2-deficient mouse lung via RNA-Seq

Turkish Journal of Biology.

Source: ORCID
Added: August 5, 2023

2021 journal article

Co-infections of two carbapenemase-producing Enterobacter hormaechei clinical strains isolated from the same diabetes individual in China

Journal of Medical Microbiology.

Source: ORCID
Added: August 5, 2023

2021 journal article

Complete genome sequence and probiotic properties of Lactococcus petauri LZys1 isolated from healthy human gut

Journal of Medical Microbiology, 70(8).

By: O. Li*, H. Zhang*, W. Wang*, Y. Liang*, W. Chen*, A. Din*, L. Li*, Y. Zhou*

MeSH headings : Animals; Bacteria / growth & development; Bacteria / pathogenicity; Base Sequence; Feces / microbiology; Gastrointestinal Tract / microbiology; Genes, Bacterial; Genome, Bacterial; Humans; Lactococcus / cytology; Lactococcus / genetics; Lactococcus / isolation & purification; Lactococcus / physiology; Male; Molecular Sequence Annotation; Moths / microbiology; Phylogeny; Polysaccharides, Bacterial / biosynthesis; Polysaccharides, Bacterial / genetics; Probiotics; Whole Genome Sequencing; Young Adult
Source: ORCID
Added: August 5, 2023

2021 journal article

Gut microbiome colonization and development in neonatal ruminants: Strategies, prospects, and opportunities

Animal Nutrition.

Source: ORCID
Added: August 5, 2023

2021 journal article

Implication of ferroptosis in aging

Cell Death Discovery.

Source: ORCID
Added: August 5, 2023

2021 journal article

Microbiota Targeted Interventions of Probiotic Lactobacillus as an Anti-Ageing Approach: A Review

Antioxidants.

By: M. Ishaq*, . khan*, A. Bacha*, T. Shah*, A. Hanif*, A. Ahmad*, W. Ke*, F. Li* ...

Source: ORCID
Added: August 5, 2023

2020 journal article

Anti-atherosclerotic effects of Lactobacillus plantarum ATCC 14917 in ApoE−/− mice through modulation of proinflammatory cytokines and oxidative stress

Applied Microbiology and Biotechnology.

Source: ORCID
Added: August 5, 2023

2020 journal article

Application of a Faecalibacterium 16S rDNA genetic marker for species identification of dog fecal waste

Environmental Science and Pollution Research.

Source: ORCID
Added: August 5, 2023

2020 journal article

Bacterial association and comparison between lung and intestine in rats

Bioscience Reports, 40(4).

By: T. Liu*, C. Zhang*, A. Din*, N. Li*, Q. Wang*, J. Yu*, Z. Xu*, C. Li* ...

MeSH headings : Animals; Bacteria / genetics; Bacteria / immunology; DNA, Bacterial / isolation & purification; Feces / microbiology; Gastrointestinal Microbiome / genetics; Lung / microbiology; Male; Models, Animal; Phylogeny; RNA, Ribosomal, 16S / genetics; Rats; Rats, Wistar; Sequence Analysis, DNA; Specific Pathogen-Free Organisms
Source: ORCID
Added: August 5, 2023

2020 journal article

High incidence and characteristic of PRRSV and resistant bacterial Co-Infection in pig farms

Microbial Pathogenesis, 149, 104536.

By: XiangjinYan, J. Zeng*, X. Li*, Z. Zhang*, A. Din*, K. Zhao*, Y. Zhou*

Source: ORCID
Added: August 5, 2023

2020 journal article

Inhibitory effect of Bifidobacterium bifidum ATCC 29521 on colitis and its mechanism

Journal of Nutritional Biochemistry, 79.

By: A. Din*, A. Hassan*, Y. Zhu*, K. Zhang*, Y. Wang*, T. Li*, Y. Wang*, G. Wang*

MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Antioxidants / pharmacology; Bifidobacterium bifidum; Colitis, Ulcerative / chemically induced; Colitis, Ulcerative / drug therapy; Colitis, Ulcerative / metabolism; Colon / metabolism; Cytokines / metabolism; Dextran Sulfate / adverse effects; Disease Models, Animal; Dysbiosis / chemically induced; Dysbiosis / drug therapy; Gastrointestinal Microbiome / drug effects; Interleukin-1beta / metabolism; Male; Mice; Mice, Inbred C57BL; MicroRNAs / metabolism; NF-kappa B / metabolism; Probiotics / administration & dosage; Probiotics / pharmacology; Tumor Necrosis Factor-alpha / metabolism
Source: ORCID
Added: August 5, 2023

2020 journal article

SARS-CoV-2 Microbiome Dysbiosis Linked Disorders and Possible Probiotics Role

Biomedicine & Pharmacotherapy, 11, 110947.

By: A. Din*, M. Mazhar, M. Wasim, W. Ahmad, A. Bibi, A. Hassan, N. Ali, W. Gang ...

Source: ORCID
Added: August 5, 2023

2020 journal article

SARS-CoV-2 microbiome dysbiosis linked disorders and possible probiotics role

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 11. http://europepmc.org/abstract/PMC/PMC7657099

By: A. Din, M. Mazhar, M. Wasim, W. Ahmad, A. Bibi, A. Hassan, N. Ali, W. Gang ...

Source: ORCID
Added: August 5, 2023

2020 journal article

The Role of Agriculture in the Dissemination of Class 1 Integrons, Antimicrobial Resistance, and Diversity of Their Gene Cassettes in Southern China

Genes, 11(9), 1014.

By: N. Ali*, Y. Lin*, Z. Qing*, D. Xiao*, A. Din*, I. Ali*, T. Lian*, B. Chen*, R. Wen*

Source: ORCID
Added: August 5, 2023

2019 journal article

Amelioration of TMAO through probiotics and its potential role in atherosclerosis

Applied Microbiology and Biotechnology, 103(23-24), 9217–9228.

By: A. Din*, A. Hassan*, Y. Zhu*, T. Yin*, H. Gregersen* & G. Wang*

MeSH headings : Animals; Atherosclerosis / physiopathology; Atherosclerosis / prevention & control; Humans; Metabolomics; Methylamines / antagonists & inhibitors; Methylamines / metabolism; Mice; MicroRNAs; Microbiota; Probiotics / therapeutic use
Source: ORCID
Added: August 5, 2023

2019 journal article

Beneficial effects of Enterococcus faecalis in hypercholesterolemic mice on cholesterol transportation and gut microbiota

Applied Microbiology and Biotechnology, 103(7), 3181–3191.

By: Y. Zhu*, T. Li*, A. Din*, A. Hassan*, Y. Wang* & G. Wang*

MeSH headings : ATP Binding Cassette Transporter, Subfamily G, Member 5 / genetics; ATP Binding Cassette Transporter, Subfamily G, Member 8 / genetics; Administration, Oral; Animals; Bifidobacterium / isolation & purification; Biological Transport; Cholesterol / blood; Cholesterol / metabolism; Enterococcus faecalis / metabolism; Gastrointestinal Microbiome; Hypercholesterolemia / therapy; Lactobacillus / isolation & purification; Lipid Metabolism; Lipoproteins / genetics; Liver / metabolism; Male; Mice; Mice, Inbred C57BL; Microbial Interactions
Source: ORCID
Added: August 5, 2023

2019 journal article

Effect of simulated microgravity induced PI3K-nos2b signalling on zebrafish cardiovascular plexus network formation

Journal of Biomechanics, 87, 83–92.

By: X. Xie, D. Lei*, Q. Zhang*, Y. Wang*, L. Wen*, Z. Ye*, A. Ud Din*, D. Jia*, A. Apicella*, G. Wang

MeSH headings : Animals; Cardiovascular Physiological Phenomena; Embryo, Nonmammalian; Morphogenesis; Neovascularization, Physiologic / physiology; Nitric Oxide / metabolism; Nitric Oxide Synthase Type II / metabolism; Phosphatidylinositol 3-Kinase / metabolism; Signal Transduction / physiology; Weightlessness; Zebrafish / embryology
Source: ORCID
Added: August 5, 2023

2019 journal article

Updates in understanding the hypocholesterolemia effect of probiotics on atherosclerosis

Applied Microbiology and Biotechnology, 103(15), 5993–6006.

By: A. Hassan*, A. Din*, Y. Zhu*, K. Zhang*, T. Li*, Y. Wang*, Y. Luo*, G. Wang*

MeSH headings : Animals; Atherosclerosis / physiopathology; Atherosclerosis / prevention & control; Cholesterol / metabolism; Humans; Hypercholesterolemia / complications; Hypercholesterolemia / therapy; Probiotics / administration & dosage; Probiotics / pharmacology
Source: ORCID
Added: August 5, 2023

2018 journal article

An overview on the progress and development on metals/non-metal catalyzed cyanation reactions

Inorganica Chimica Acta, 469, 408–423.

By: T. Najam*, S. Shah*, K. Mehmood*, A. Din*, S. Rizwan*, M. Ashfaq*, S. Shaheen*, A. Waseem*

Source: ORCID
Added: August 5, 2023

2016 journal article

The de-etiolated 1 homolog of arabidopsis modulates the ABA signaling pathway and ABA biosynthesis in rice

Plant Physiology, 171(2), 1259–1276.

By: G. Zang*, H. Zou*, Y. Zhang*, Z. Xiang*, J. Huang*, L. Luo*, C. Wang*, K. Lei* ...

Source: ORCID
Added: August 5, 2023

Employment

Updated: August 5th, 2023 12:42

2023 - present

North Carolina State University Raleigh, North Carolina, US
Postdoctoral Fellow

2022 - 2023

University of Maryland Dental School Baltimore, MD, US
Postdoctoral Fellow Department of Microbial Pathogenesis

2022 - 2022

West China Hospital, Sichuan University Chengdu , Chengdu , CN
Postdoctoral Fellow Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, Sichuan, P. R. China.

2019 - 2022

Southwest Medical University Luzhou, Sichuan, CN
Scientific Researcher Drug Discovery Research Center

Education

Updated: September 1st, 2023 13:31

2015 - 2019

Chongqing University Chongqing, Shapingba/Chongqing, CN
PhD College of Bioengineering