Alex Dornburg

Works (11)

Updated: April 23rd, 2025 19:17

2024 article

Investigating the Impact of Whole-Genome Duplication on Transposable Element Evolution in Teleost Fishes

Mallik, R., Wcisel, D. J., Near, T. J., Yoder, J. A., & Dornburg, A. (2024, December 23). (A. Betancourt, Ed.). Genome Biology and Evolution, Vol. 17.

By: R. Mallik *, D. Wcisel n, T. Near *, J. Yoder n  & A. Dornburg*

Ed(s): A. Betancourt

author keywords: living fossil; teleost genome duplication; transposable elements; Actinopterygii; Teleostei
MeSH headings : Animals; DNA Transposable Elements; Evolution, Molecular; Gene Duplication; Genome; Fishes / genetics; Phylogeny
topics (OpenAlex): Chromosomal and Genetic Variations; Genomics and Phylogenetic Studies; Studies on Chitinases and Chitosanases
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 23, 2024

2023 article

A chromosome-level genome assembly of longnose gar, Lepisosteus osseus

Mallik, R., Carlson, K. B., Wcisel, D. J., Fisk, M., Yoder, J. A., & Dornburg, A. (2023, April 29). (N. Whiteman, Ed.). G3 Genes Genomes Genetics, Vol. 4.

By: R. Mallik *, K. Carlson n, D. Wcisel n, M. Fisk*, J. Yoder n  & A. Dornburg*

Ed(s): N. Whiteman

author keywords: teleost genome duplication; holostei; longnose gar; chromosome level assembly; living fossil; transposable elements
MeSH headings : Humans; Animals; Evolution, Molecular; Fishes / genetics; Genome; Chromosomes / genetics; Phylogeny
topics (OpenAlex): Genetic diversity and population structure; Genomics and Phylogenetic Studies; Identification and Quantification in Food
TL;DR: The first high quality reference genome assembly and annotation of the longnose gar (Lepisosteus osseus) is reported, highlighting the potential utility of holostean genomes for understanding the evolution of vertebrate repetitive elements and providing a critical reference for comparative genomic studies utilizing ray-finned fish models. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 12, 2023

2023 article

Ancient fish lineages illuminate toll-like receptor diversification in early vertebrate evolution

Carlson, K. B., Nguyen, C., Wcisel, D. J., Yoder, J. A., & Dornburg, A. (2023, August 9). Immunogenetics, Vol. 8.

By: K. Carlson n, C. Nguyen *, D. Wcisel n, J. Yoder n  & A. Dornburg*

author keywords: Vertebrate; TLR; Immunogenetics; Evolution; Actinopterygii; Polypterus senegalus
MeSH headings : Animals; Phylogeny; Vertebrates / genetics; Toll-Like Receptors / genetics; Fishes / genetics; Immunity, Innate / genetics; Evolution, Molecular
topics (OpenAlex): Immune Response and Inflammation; Aquaculture disease management and microbiota; Antimicrobial Peptides and Activities
TL;DR: This work investigates the diversification of vertebrate Toll-like receptors (TLRs), one of the most ancient and well conserved innate immune receptor families found across the Tree of Life, integrating genomic data that represent all major vertebrate lineages with new transcriptomic data from Polypteriformes, the earliest diverging ray-finned fish lineage. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 28, 2023

2022 article

A highly diverse set of novel immunoglobulin-like transcript (NILT) genes in zebrafish indicates a wide range of functions with complex relationships to mammalian receptors

Wcisel, D. J., Dornburg, A., McConnell, S. C., Hernandez, K. M., Andrade, J., Jong, J. L. O., … Yoder, J. A. (2022, July 22). Immunogenetics, Vol. 7.

By: D. Wcisel n, A. Dornburg*, S. McConnell *, K. Hernandez *, J. Andrade *, J. Jong *, G. Litman*, J. Yoder n 

author keywords: Innate immunity; Gene content variation; Alternative immune haplotypes; Gene family evolution; Mammalian CD300 (CMRF35); Mammalian NCR2 (NKp44)
MeSH headings : Animals; Zebrafish / genetics; Amino Acid Sequence; Receptors, Immunologic / genetics; Genome / genetics; Immunoglobulins / genetics; Phylogeny; Mammals / genetics
topics (OpenAlex): Aquaculture disease management and microbiota; Immune Cell Function and Interaction; Invertebrate Immune Response Mechanisms
TL;DR: A higher level of genetic complexity, interindividual variation, and sequence diversity for NILTs than previously described is revealed, suggesting that this gene family likely plays multiple roles in host immunity. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 23, 2022

2022 article

On the relationship between extant innate immune receptors and the evolutionary origins of jawed vertebrate adaptive immunity

Dornburg, A., & Yoder, J. A. (2022, January 4). Immunogenetics, Vol. 74, pp. 111–128.

By: A. Dornburg* & J. Yoder n 

author keywords: Bowfin and gar (Holostei); Immune system evolution; Joining domains; Origins of V(D)J recombination; Zebrafish
MeSH headings : Adaptive Immunity / genetics; Animals; Evolution, Molecular; Immunity, Innate / genetics; Immunoglobulins / genetics; Phylogeny; Receptors, Antigen, T-Cell; Receptors, Immunologic / genetics; Vertebrates / genetics
topics (OpenAlex): Immune Cell Function and Interaction; Aquaculture disease management and microbiota; T-cell and B-cell Immunology
TL;DR: A conceptual model of the evolutionary origins and phylogenetic distribution of known VJ-containing innate immune receptors is provided, highlighting opportunities for future comparative research that are empowered by this emerging evolutionary perspective. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 4, 2022

2022 article

Placing human gene families into their evolutionary context

Dornburg, A., Mallik, R., Wang, Z., Bernal, M. A., Thompson, B., Bruford, E. A., … Townsend, J. P. (2022, November 11). Human Genomics.

By: A. Dornburg*, R. Mallik *, Z. Wang *, M. Bernal*, B. Thompson, E. Bruford *, D. Nebert*, V. Vasiliou ...

MeSH headings : Animals; Humans; Evolution, Molecular; Genomics; Genome; Base Sequence; Phylogeny
topics (OpenAlex): Genomics and Phylogenetic Studies; CRISPR and Genetic Engineering; RNA and protein synthesis mechanisms
TL;DR: How homology can provide insights into the genes and gene families associated with immune response, cancer biology, vision, chemosensation, and metabolism, by revealing similarity in processes among distant species is shown. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: November 28, 2022

2022 article

Transcriptome annotation reveals minimal immunogenetic diversity among Wyoming toads, Anaxyrus baxteri

Carlson, K. B., Wcisel, D. J., Ackerman, H. D., Romanet, J., Christiansen, E. F., Niemuth, J. N., … Yoder, J. A. (2022, April 28). Conservation Genetics, Vol. 4.

By: K. Carlson n, D. Wcisel n, H. Ackerman  n, J. Romanet n, E. Christiansen n, J. Niemuth n , C. Williams n, M. Breen n  ...

author keywords: Amphibian; Bufonidae; Immunogenetics; MHC; TLR; Transcriptomics
topics (OpenAlex): Amphibian and Reptile Biology; Aquaculture disease management and microbiota; Animal Behavior and Reproduction
TL;DR: Comparison transcriptomics is used to examine the diversity of toll-like receptors and major histocompatibility complex sequences across three individual Wyoming toads and finds reduced diversity at MHC genes compared to bufonid species with a similar history of bottleneck events. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 29, 2022

2021 article

Assessing temporal biases across aggregated historical spatial data: a case study of North Carolina’s freshwater fishes

Sigler, K., Warren, D., Tracy, B., Forrestel, E., Hogue, G., & Dornburg, A. (2021, December 1). Ecosphere.

By: K. Sigler n, D. Warren *, B. Tracy*, E. Forrestel *, G. Hogue * & A. Dornburg*

author keywords: biodiversity survey; camera trap surveillance; environmental DNA; environmental niche modeling; museum records
topics (OpenAlex): Species Distribution and Climate Change; Wildlife Ecology and Conservation; Genetic diversity and population structure
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13. Climate Action (Web of Science)
14. Life Below Water (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: January 10, 2022

2021 article

Comparing the dietary niche overlap and ecomorphological differences between invasive Hemidactylus mabouia geckos and a native gecko competitor

Lamb, A. D., Lippi, C. A., Watkins‐Colwell, G. J., Jones, A., Warren, D. L., Iglesias, T. L., … Dornburg, A. (2021, December 1). Ecology and Evolution.

By: A. Lamb n, C. Lippi *, G. Watkins‐Colwell *, A. Jones *, D. Warren *, T. Iglesias *, M. Brandley *, A. Dornburg*

author keywords: food web; invasive species; trophic ecology; urbanization; vertebrate biodiversity loss
topics (OpenAlex): Species Distribution and Climate Change; Animal Ecology and Behavior Studies; Amphibian and Reptile Biology
TL;DR: Findings provide the first support for the hypotheses that invasive H. mabouia and native P. martini overlap in prey resources and that H.mabouIA possess ecomorphological advantages over P.martini. (via Semantic Scholar)
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11. Sustainable Cities and Communities (OpenAlex)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: January 3, 2022

2021 article

The bowfin genome illuminates the developmental evolution of ray-finned fishes

Thompson, A. W., Hawkins, M. B., Parey, E., Wcisel, D. J., Ota, T., Kawasaki, K., … Braasch, I. (2021, August 30). Nature Genetics, Vol. 8.

By: A. Thompson *, M. Hawkins *, E. Parey *, D. Wcisel n, T. Ota *, K. Kawasaki *, E. Funk *, M. Losilla * ...

MeSH headings : Animals; Biological Evolution; Chromatin / genetics; Evolution, Molecular; Fishes; Genome / genetics; Skates, Fish / genetics; Skates, Fish / immunology; Skates, Fish / physiology; Whole Genome Sequencing
topics (OpenAlex): Genomics and Phylogenetic Studies; Chromosomal and Genetic Variations; Aquaculture disease management and microbiota
TL;DR: A chromosome-level genome assembly for bowfin is presented that enables gene-order analyses, settling long-debated neopterygian phylogenetic relationships and investigates the evolution of immune, scale, respiratory and fin skeletal systems and identifies hundreds of gene-regulatory loci conserved across vertebrates. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 7, 2021

2019 article

Are Geckos Paratenic Hosts for Caribbean Island Acanthocephalans? Evidence from Gonatodes antillensis and a Global Review of Squamate Reptiles Acting as Transport Hosts

Dornburg, A., Lamb, A. D., Warren, D., Watkins-Colwell, G. J., Lewbart, G. A., & Flowers, J. (2019, April 1). Bulletin of the Peabody Museum of Natural History, Vol. 60, pp. 55–79.

By: A. Dornburg*, A. Lamb n, D. Warren *, G. Watkins-Colwell *, G. Lewbart n  & J. Flowers n

author keywords: Acanthocephala; intestinal helminths; cats; parasite; trophic transmission; mammals; birds; host-parasite interactions; vector species
topics (OpenAlex): Parasite Biology and Host Interactions; Bird parasitology and diseases; Primate Behavior and Ecology
TL;DR: Evidence is found that the ability of squamate reptiles to act as transport hosts is a pervasive feature across their Tree of Life, suggesting that these animals may serve as important vectors for transporting parasites between intermediate and definitive hosts. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 29, 2019

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