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2023 journal article
Effects of sterilization methods on gelatin methacryloyl hydrogel properties and macrophage gene expression in vitro
BIOMEDICAL MATERIALS, 18(1).
2023 journal article
Heparin Affinity-Based IL-4 Delivery to Modulate Macrophage Phenotype and Endothelial Cell Activity In Vitro
ACS APPLIED MATERIALS & INTERFACES, 15(23), 27457–27470.
2023 journal article
Influence of Fibrinogen Concentrate on Neonatal Clot Structure When Administered Ex Vivo After Cardiopulmonary Bypass
ANESTHESIA AND ANALGESIA, 137(3), 682–690.
2023 article
Molecular Engineering of Cyclic Azobenzene-Peptide Hybrid Ligands for the Purification of Human Blood Factor VIII via Photo-Affinity Chromatography
Prodromou, R., Moore, B. D., Chu, W., Deal, H., San Miguel, A., Brown, A. C., … Menegatti, S. (2023, January 25). ADVANCED FUNCTIONAL MATERIALS, Vol. 1.
2023 review
Recent Advances in Blood Cell-Inspired and Clot-Targeted Thrombolytic Therapies
[Review of ]. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2023.
2022 journal article
A Unique Crustacean-Based Chitin Platform to Reduce Self-Aggregation of Polysaccharide Nanofibers
FIBERS, 10(10).
2022 review
Biomaterials for Hemostasis
[Review of ]. ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 24, 111–135.
2022 article
COVID-19 patient fibrinogen produces dense clots with altered polymerization kinetics, partially explained by increased sialic acid
Moiseiwitsch, N., Zwennes, N., Szlam, F., Sniecinski, R., & Brown, A. (2022, October 5). JOURNAL OF THROMBOSIS AND HAEMOSTASIS.
2022 article
Elucidating the combinatorial effect of substrate stiffness and surface viscoelasticity on cellular phenotype
Chester, D., Lee, V., Wagner, P., Nordberg, M., Fisher, M. B., & Brown, A. C. (2022, February 1). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A.
2022 journal article
Inhalable dry powder mRNA vaccines based on extracellular vesicles
Matter, 5(9), 2960–2974.
2022 article
On-demand, remote and lossless manipulation of biofluid droplets
Wang, W., Sun, J., Vallabhuneni, S., Pawlowski, B., Vahabi, H., Nellenbach, K., … Kota, A. K. (2022, September 7). MATERIALS HORIZONS.
2022 article
Plasma-Induced Diallyldimethylammonium Chloride Antibacterial Hernia Mesh
Wang, Z., Hamedi, H., Zhang, F., El-Shafei, A., Brown, A. C., Gluck, J. M., & King, M. W. (2022, November 29). ACS APPLIED BIO MATERIALS, Vol. 11.
2022 article
Platelet-mimicking procoagulant nanoparticles: Potential strategies for mitigating blood shortages
Nellenbach, K., & Brown, A. C. (2022, April 19). JOURNAL OF THROMBOSIS AND HAEMOSTASIS.
2022 journal article
Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture
ACTA BIOMATERIALIA, 138, 208–217.
2021 journal article
Differential sialic acid content in adult and neonatal fibrinogen mediates differences in clot polymerization dynamics
BLOOD ADVANCES, 5(23), 5202–5214.
2021 article
Ex Vivo and In Vivo Evaluation of Fibrinogen Concentrate to Mitigate Post-Surgical Bleeding in Neonates
Moiseiwitsch, N., Nellenbach, K. A., Guzzetta, N. A., Brown, A. C., & Downey, L. (2021, November 23). BLOOD, Vol. 138.
2021 journal article
Fibrin-modulating nanogels for treatment of disseminated intravascular coagulation
BLOOD ADVANCES, 5(3), 613–627.
2021 article
Fibrin-specific poly(N-isopropylacrylamide) nanogels for targeted delivery of tissue-type plasminogen activator to treat thrombotic complications are well tolerated in vivo
Mihalko, E. P., Nellenbach, K., Krishnakumar, M., Moiseiwitsch, N., Sollinger, J., Cooley, B. C., & Brown, A. C. (2021, December 11). BIOENGINEERING & TRANSLATIONAL MEDICINE.
2021 journal article
Modeling and Parameter Subset Selection for Fibrin Polymerization Kinetics with Applications to Wound Healing
BULLETIN OF MATHEMATICAL BIOLOGY, 83(5).
2021 article
Multivalent Aptamer-Functionalized Single-Strand RNA Origami as Effective, Target-Specific Anticoagulants with Corresponding Reversal Agents
Krissanaprasit, A., Key, C. M., Froehlich, K., Pontula, S., Mihalko, E., Dupont, D. M., … LaBean, T. H. (2021, April 21). ADVANCED HEALTHCARE MATERIALS.
2021 review
Neonatal coagulopathies: A review of established and emerging treatments
[Review of ]. EXPERIMENTAL BIOLOGY AND MEDICINE, 246(12), 1447–1457.
2021 article
Platelet-like particles reduce coagulopathy-related and neuroinflammatory pathologies post-experimental traumatic brain injury
Todd, J., Bharadwaj, V. N., Nellenbach, K., Nandi, S., Mihalko, E., Copeland, C., … Stabenfeldt, S. E. (2021, June 11). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS.
2021 journal article
Synthesis of sonicated fibrin nanoparticles that modulate fibrin clot polymerization and enhance angiogenic responses
COLLOIDS AND SURFACES B-BIOINTERFACES, 204.
2021 journal article
Synthetic Platelet Microgels Containing Fibrin Knob B Mimetic Motifs Enhance Clotting Responses
ADVANCED THERAPEUTICS, 4(5).
2020 review
Biomimetic antimicrobial material strategies for combating antibiotic resistant bacteria
[Review of ]. BIOMATERIALS SCIENCE, 8(4), 1089–1100.
2020 review
Clot Structure and Implications for Bleeding and Thrombosis
[Review of ]. SEMINARS IN THROMBOSIS AND HEMOSTASIS, 46(1), 96–104.
2020 journal article
Development of Biomimetic Antimicrobial Platelet-Like Particles Comprised of Microgel Nanogold Composites
REGENERATIVE ENGINEERING AND TRANSLATIONAL MEDICINE, 6(3), 299–309.
2020 journal article
Mechanical properties of tissue formed in vivo are affected by 3D-bioplotted scaffold microarchitecture and correlate with ECM collagen fiber alignment
CONNECTIVE TISSUE RESEARCH, 61(2), 190–204.
2020 review
Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies
[Review of ]. JOURNAL OF MATERIALS CHEMISTRY B, 8(32), 7062–7075.
2020 journal article
Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet-like particles
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 108(6), 2599–2609.
2020 article
Neonatal Fibrin Scaffolds Promote Enhanced Cell Adhesion, Migration, and Wound Healing In Vivo Compared to Adult Fibrin Scaffolds
CELLULAR AND MOLECULAR BIOENGINEERING.
2020 journal article
Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 577, 406–418.
2020 journal article
Ultrasonic Microplotting of Microgel Bioinks
ACS APPLIED MATERIALS & INTERFACES, 12(42), 47309–47319.
2020 journal article
Ultrasound Enhanced Synthetic Platelet Therapy for Augmented Wound Repair
ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(5), 3026–3036.
2019 review
Biomimetic Strategies To Treat Traumatic Brain Injury by Leveraging Fibrinogen
[Review of ]. BIOCONJUGATE CHEMISTRY, 30(7), 1951–1956.
2019 journal article
Fibrin Nanoparticles Coupled with Keratinocyte Growth Factor Enhance the Dermal Wound-Healing Rate
ACS APPLIED MATERIALS & INTERFACES, 11(4), 3771–3780.
2019 article
Maintaining Hemostatic Balance in Treating Disseminated Intravascular Coagulation
Brown, A. C., & Levy, J. H. (2019, September). ANESTHESIOLOGY, Vol. 131, pp. 459–461.
2019 journal article
Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes
BIOMATERIALS SCIENCE, 7(2), 669–682.
2019 article
Wound Healing and the Host Response in Regenerative Engineering
ENCYCLOPEDIA OF BIOMEDICAL ENGINEERING, VOL 1, pp. 707–718.
2018 journal article
Biomimetic Microgels with Controllable Deformability Improve Healing Outcomes
ADVANCED BIOSYSTEMS, 2(10).
2018 journal article
Enhancing clot properties through fibrin-specific self-cross-linked PEG side-chain microgels
COLLOIDS AND SURFACES B-BIOINTERFACES, 166, 89–97.
2018 article
Fibrin biomaterials for tissue regeneration and repair
PEPTIDES AND PROTEINS AS BIOMATERIALS FOR TISSUE REGENERATION AND REPAIR, pp. 151–173.
2018 journal article
Interdigitated microelectronic bandage augments hemostasis and clot formation at low applied voltage in vitro and in vivo
LAB ON A CHIP, 18(19), 2985–2993.
2018 review
Material Strategies for Modulating Epithelial to Mesenchymal Transitions
[Review of ]. ACS BIOMATERIALS SCIENCE & ENGINEERING, 4(4), 1149–1161.
2018 journal article
Study of Poly(N-isopropylacrylamide-co-acrylic acid) (pNIPAM) Microgel Particle Induced Deformations of Tissue-Mimicking Phantom by Ultrasound Stimulation
LANGMUIR, 34(4), 1457–1465.
2018 journal article
Targeted Treatment of Ischemic and Fibrotic Complications of Myocardial Infarction Using a Dual-Delivery Microgel Therapeutic
ACS Nano, 12(8), 7826–7837.
2018 journal article
Targeted repair of heart injury by stem cells fused with platelet nanovesicles
NATURE BIOMEDICAL ENGINEERING, 2(1), 17–26.
2018 journal article
Viscoelastic properties of microgel thin films control fibroblast modes of migration and pro-fibrotic responses
BIOMATERIALS, 185, 371–382.
2017 journal article
Characterizing Cell Migration Within Three-dimensional In Vitro Wound Environments
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (126).
2017 journal article
Detection of an Integrin-Binding Mechanoswitch within Fibronectin during Tissue Formation and Fibrosis
ACS NANO, 11(7), 7110–7117.
2017 journal article
Peptide Mimetic Drugs for Modulating Thrombosis and Hemostasis
DRUG DEVELOPMENT RESEARCH, 78(6), 236–244.
2017 journal article
Single-platelet nanomechanics measured by high-throughput cytometry
NATURE MATERIALS, 16(2), 230–235.
2017 review
The role of biophysical properties of provisional matrix proteins in wound repair
[Review of ]. MATRIX BIOLOGY, 60-61, 124–140.
2016 article
Fibrin Network Changes in Neonates after Cardiopulmonary Bypass
Brown, A. C., Hannan, R. H., Timmins, L. H., Fernandez, J. D., Barker, T. H., & Guzzetta, N. A. (2016, May). ANESTHESIOLOGY, Vol. 124, pp. 1021–1031.
2016 review
Platelet-mimetic strategies for modulating the wound environment and inflammatory responses
[Review of ]. EXPERIMENTAL BIOLOGY AND MEDICINE, 241(10), 1138–1148.
2015 journal article
Chondroitin Sulfate Glycosaminoglycan Hydrogels Create Endogenous Niches for Neural Stem Cells
BIOCONJUGATE CHEMISTRY, 26(12), 2336–2349.
2015 journal article
Integrin alpha 3 beta 1 binding to fibronectin is dependent on the ninth type III repeat
Journal of Biological Chemistry, 290(42), 25534–25547.
2015 journal article
Molecular interference of fibrin's divalent polymerization mechanism enables modulation of multiscale material properties
Biomaterials, 49, 27–36.
2015 journal article
Ultrasoft, highly deformable microgels
Soft Matter, 11(10), 2018–2028.
2014 journal article
Direct observation of ligand-induced receptor dimerization with a bioresponsive hydrogel
RSC Advances, 4(110), 65173–65175.
2014 journal article
Fibrin Fibers: Blocking the B:B Knob-Pocket Interaction
Biophysical Journal, 106(2), 614a.
2014 journal article
Fibrin-based biomaterials: Modulation of macroscopic properties through rational design at the molecular level
Acta Biomaterialia, 10(4), 1502–1514.
2014 journal article
Learning from nature – Novel synthetic biology approaches for biomaterial design
Acta Biomaterialia, 10(4), 1761–1769.
2014 journal article
Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation
Proceedings of the National Academy of Sciences, 111(40), 14430–14435.
2014 journal article
Ultrasoft microgels displaying emergent platelet-like behaviours
Nature Materials, 13(12), 1108–1114.
2013 journal article
Colloid-matrix assemblies in regenerative medicine
Current Opinion in Colloid & Interface Science, 18(5), 393–405.
2013 journal article
Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions
The Journal of Pathology, 229(1), 25–35.
2013 journal article
The Mechanical Properties of Modified Fibrin Fibers: Blocking the B-b Knob-Pocket Interaction
Biophysical Journal, 104(2), 512a–513a.
2012 journal article
Directing epithelial to mesenchymal transition through engineered microenvironments displaying orthogonal adhesive and mechanical cues
Journal of Biomedical Materials Research Part A, 100A(8), 2119–2127.
2010 journal article
Continuously perfused, non-cross-contaminating microfluidic chamber array for studying cellular responses to orthogonal combinations of matrix and soluble signals
Lab Chip, 10(5), 571–580.