Ashley Carson Brown

Microgels for Biomedical Applications

Pandit, S., & Brown, A. C. (2026, January 9). (Vol. 1). Vol. 1.

Colloidal-Fibrillar Composite Gels Demonstrate Structural Reinforcement, Secondary Fibrillar Alignment, and Improved Vascular Healing Outcomes

Communications Engineering, 4, 67.

Convergence research in matrix biology and biomaterials science

Alge, D. L., & Brown, A. (2025, June 24). Matrix Biology Plus, Vol. 6.

Distinguishing the Metabolic Effect of Fetal and Adult Fibrinogen on Human Fibroblast Cell Culture by IR-MALDESI Mass Spectrometry Imaging

Joignant, A. N., Sheridan, A., Brown, A. C., & Muddiman, D. C. (2025, April 7). Journal of the American Society for Mass Spectrometry, Vol. 4.

From saccharides to synthetics: exploring biomaterial scaffolds as cell transduction enhancers

Mallory, M., Johnson, E. G., Saha, S., Pandit, S., McCune, J. T., Dennis, M., … Brudno, Y. (2025, January 1). Biomaterials Science, Vol. 5.

Noninvasive Fibrin Targeting Colloid‐Mediated Intra‐Articular Repair

Journal of Biomedical Materials Research Part A, 113(4).

Structure-based design of therapeutics to control hemostasis

Tucker, L. J., Hilmas, K., & Brown, A. C. (2025, March 25). Blood, Vol. 146.

A Functional RNA-Origami as Direct Thrombin Inhibitor with Fast-acting and Specific Single-Molecule Reversal Agents in vivo model

Molecular Therapy, 5.

Clot-Targeted Nanogels for Dual-Delivery of AntithrombinIII and Tissue Plasminogen Activator to Mitigate Disseminated Intravascular Coagulation Complications

Sheridan, A., Nellenbach, K., Pandit, S., Byrnes, E., Hardy, G., Lutz, H., … Brown, A. C. (2024, June 5). ACS Nano, Vol. 6.

Controlled Stiffness of Direct-Write, Near-Field Electrospun Gelatin Fibers Generates Differences in Tenocyte Morphology and Gene Expression

Journal of Biomechanical Engineering, 146(9).

Effect of In Vivo Administration of Fibrinogen Concentrate Versus Cryoprecipitate on Ex Vivo Clot Degradation in Neonates Undergoing Cardiac Surgery

Downey, L. A., Moiseiwitsch, N., Nellenbach, K., Xiang, Y., Brown, A. C., & Guzzetta, N. A. (2024, August 8). Anesthesia & Analgesia, Vol. 141, pp. 240–251.

Erratum to ‘Illustrated State-of-the-Art Capsules of the ISTH 2024 Congress’ [Research and Practice in Thrombosis and Haemostasis Volume 8, Issue 4, May 2024, 102432]

Ward, C., Curry, N., El-Ekiaby, M., Jurk, K., Versteeg, H. H., Keragala, C., … Marín-Quilez, A. (2024, July 1). Research and Practice in Thrombosis and Haemostasis, Vol. 8.

Fighting fibrin with fibrin: Vancomycin delivery into coagulase‐mediated Staphylococcus aureus biofilms via fibrin‐based nanoparticle binding

Journal of Biomedical Materials Research Part A, 112(12), 2071–2085.

Illustrated State-of-the-Art Capsules of the ISTH 2024 Congress

Ward, C., Curry, N., El-Ekiaby, M., Jurk, K., Versteeg, H. H., Keragala, C., … Sholzberg, M. (2024, May 1). Research and Practice in Thrombosis and Haemostasis, Vol. 8.

In-depth characterization of N-glycosylation and sialic acid content in fetal and adult fibrinogen

Palomino, T. V., Sheridan, A., Muddiman, D. C., & Brown, A. C. (2024, November 1). Research and Practice in Thrombosis and Haemostasis, Vol. 8.

Injury-on-a-chip for modelling microvascular trauma-induced coagulation

Lab on a Chip, 25(3), 440–453.

Peptide ligands for the universal purification of exosomes by affinity chromatography

Biotechnology and Bioengineering, 121(11), 3484–3501.

Point-of-Care Cardiac Troponin I Assay Evaluation in New Zealand White Rabbits (Oryctolagus cuniculus)

Ozawa, S. M., Pierce, K. V., Thomson, A., Moiseiwitsch, N. A., Stephens, J., LeGrand, J., … Mochizuki, H. (2024, September 5). Journal of the American Association for Laboratory Animal Science, Vol. 63, pp. 669–674.

Preparation and Characterization of Hydrogels Fabricated From Chitosan and Poly(vinyl alcohol) for Tissue Engineering Applications

Wang, Z., Mahmood, N., Budhathoki-Uprety, J., Brown, A. C., King, M. W., & Gluck, J. M. (2024, July 22). ACS Applied Bio Materials, Vol. 7.

Transfusion biomaterials for hemostasis

Pozy, E., & Brown, A. C. (2024, December 13). Journal of Thrombosis and Haemostasis, Vol. 23, pp. 790–803.

Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma

Science Translational Medicine, 16(742).

Utilizing multiscale engineered biomaterials to examine TGF‐β‐mediated myofibroblastic differentiation

Wound Repair and Regeneration, 3.

Biomaterials for treating sepsis-induced thromboinflammation

Frontiers Media SA.

Characteristics of Fetal Wound Healing and Inspiration for Pro-healing Materials

Biomedical Materials & Devices, 2(1), 158–167.

Heparin Affinity-Based IL-4 Delivery to Modulate Macrophage Phenotype and Endothelial Cell Activity In Vitro

ACS Applied Materials & Interfaces, 15(23), 27457–27470.

Influence of Fibrinogen Concentrate on Neonatal Clot Structure When Administered Ex Vivo After Cardiopulmonary Bypass

Anesthesia & Analgesia, 137(3), 682–690.

Microparticle Hydrogel Material Properties Emerge from Mixing-Induced Homogenization in a Poly(ethylene glycol) and Dextran Aqueous Two-Phase System

Macromolecules, 56(21), 8518–8528.

Molecular Engineering of Cyclic Azobenzene‐Peptide Hybrid Ligands for the Purification of Human Blood Factor VIII via Photo‐Affinity Chromatography

Advanced Functional Materials, 33(14), 2213881.

Recent Advances in Blood Cell-Inspired and Clot-Targeted Thrombolytic Therapies

Journal of Tissue Engineering and Regenerative Medicine, 2023, 1–14.

Simple design for membrane-free microphysiological systems to model the blood-tissue barriers

Organs-on-a-Chip, 5, 100032.

Wound‐triggered shape change microgels for the development of enhanced biomimetic function platelet‐like particles

Journal of Biomedical Materials Research Part A, 112(4), 613–624.

A Unique Crustacean-Based Chitin Platform to Reduce Self-Aggregation of Polysaccharide Nanofibers

Fibers, 10(10), 87.

Biomaterials for Hemostasis

Annual Review of Biomedical Engineering, 24(1), 111–135.

COVID‐19 patient fibrinogen produces dense clots with altered polymerization kinetics, partially explained by increased sialic acid

Journal of Thrombosis and Haemostasis, 20(12), 2909–2920.

Effects of sterilization methods on gelatin methacryloyl hydrogel properties and macrophage gene expression in vitro

Biomedical Materials, 18(1), 015015.

Elucidating the combinatorial effect of substrate stiffness and surface viscoelasticity on cellular phenotype

Journal of Biomedical Materials Research Part A, 110(6), 1224–1237.

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Matter, 5(9), 2960–2974.

On-demand, remote and lossless manipulation of biofluid droplets

Materials Horizons, 9(11), 2863–2871.

Plasma-Induced Diallyldimethylammonium Chloride Antibacterial Hernia Mesh

ACS Applied Bio Materials, 5(12), 5645–5656.

Platelet‐mimicking procoagulant nanoparticles: Potential strategies for mitigating blood shortages

Nellenbach, K., & Brown, A. C. (2022, April 19). Journal of Thrombosis and Haemostasis, Vol. 4.

Differential sialic acid content in adult and neonatal fibrinogen mediates differences in clot polymerization dynamics

BLOOD ADVANCES, Vol. 5, pp. 5202–5214.

Differential sialic acid content in adult and neonatal fibrinogen mediates differences in clot polymerization dynamics

Blood Advances, 5(23), 5202–5214.

Ex Vivo and In Vivo Evaluation of Fibrinogen Concentrate to Mitigate Post-Surgical Bleeding in Neonates

Moiseiwitsch, N., Nellenbach, K. A., Guzzetta, N. A., Brown, A. C., & Downey, L. (2021, November 5). Blood, Vol. 138.

Fibrin-modulating nanogels for treatment of disseminated intravascular coagulation

Blood Advances, 5(3), 613–627.

Fibrin‐specific poly(N‐isopropylacrylamide) nanogels for targeted delivery of tissue‐type plasminogen activator to treat thrombotic complications are well tolerated in vivo

Bioengineering & Translational Medicine, 7(2).

Modeling and Parameter Subset Selection for Fibrin Polymerization Kinetics with Applications to Wound Healing

Bulletin of Mathematical Biology, 83(5).

Multivalent Aptamer‐Functionalized Single‐Strand RNA Origami as Effective, Target‐Specific Anticoagulants with Corresponding Reversal Agents

Advanced Healthcare Materials, 10(11).

Neonatal coagulopathies: A review of established and emerging treatments

Experimental Biology and Medicine, 246(12), 1447–1457.

Platelet‐like particles reduce coagulopathy‐related and neuroinflammatory pathologies post‐experimental traumatic brain injury

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 109(12), 2268–2278.

Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture

Acta Biomaterialia, 138, 208–217.

Synthesis of sonicated fibrin nanoparticles that modulate fibrin clot polymerization and enhance angiogenic responses

Colloids and Surfaces B: Biointerfaces, 204, 111805.

Synthetic Platelet Microgels Containing Fibrin Knob B Mimetic Motifs Enhance Clotting Responses

Advanced Therapeutics, 4(5).

Comparison of Neonatal and Adult Fibrin Clot Properties between Porcine and Human Plasma

Anesthesiology, 132(5), 1091–1101.

Development of Novel Microenvironments for Promoting Enhanced Wound Healing

Current Tissue Microenvironment Reports, 1(3), 73–87.

Effect of surface interactions on the settlement of particles on a sinusoidally corrugated substrate

RSC Advances, 10(19), 11348–11356.

Fibrin‐based biomaterial systems to enhance anterior cruciate ligament healing

MEDICAL DEVICES & SENSORS, 4(1).

Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies

Journal of Materials Chemistry B, 8(32), 7062–7075.

Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet‐like particles

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 108(6), 2599–2609.

Neonatal Fibrin Scaffolds Promote Enhanced Cell Adhesion, Migration, and Wound Healing In Vivo Compared to Adult Fibrin Scaffolds

Cellular and Molecular Bioengineering, 13(5), 393–404.

Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects

Journal of Colloid and Interface Science, 577, 406–418.

Ultrasonic Microplotting of Microgel Bioinks

ACS Applied Materials & Interfaces, 12(42), 47309–47319.

Ultrasound Enhanced Synthetic Platelet Therapy for Augmented Wound Repair

ACS Biomaterials Science & Engineering, 6(5), 3026–3036.

Biomimetic Strategies To Treat Traumatic Brain Injury by Leveraging Fibrinogen

Bioconjugate Chemistry, 30(7), 1951–1956.

Biomimetic antimicrobial material strategies for combating antibiotic resistant bacteria

Biomaterials Science, 8(4), 1089–1100.

Clot Structure and Implications for Bleeding and Thrombosis

Seminars in Thrombosis and Hemostasis, 46(01), 096–104.

Development of Biomimetic Antimicrobial Platelet-Like Particles Comprised of Microgel Nanogold Composites

Regenerative Engineering and Translational Medicine, 6(3), 299–309.

Fibrin Nanoparticles Coupled with Keratinocyte Growth Factor Enhance the Dermal Wound-Healing Rate

ACS Applied Materials & Interfaces, 11(4), 3771–3780.

Maintaining Hemostatic Balance in Treating Disseminated Intravascular Coagulation

Brown, A. C., & Levy, J. H. (2019, July 1). Anesthesiology, Vol. 131, pp. 459–461.

Mechanical properties of tissue formed in vivo are affected by 3D-bioplotted scaffold microarchitecture and correlate with ECM collagen fiber alignment

Connective Tissue Research, 61(2), 190–204.

Analysis of the structural and mechanical effects of procoagulant agents on neonatal fibrin networks following cardiopulmonary bypass

Journal of Thrombosis and Haemostasis, 16(11), 2159–2167.

Biomimetic Microgels with Controllable Deformability Improve Healing Outcomes

Advanced Biosystems, 2(10).

Enhancing clot properties through fibrin-specific self-cross-linked PEG side-chain microgels

Welsch, N., Brown, A. C., Barker, T. H., & Lyon, L. A. (2018, March 2). Colloids and Surfaces B Biointerfaces, Vol. 166, pp. 89–97.

Interdigitated microelectronic bandage augments hemostasis and clot formation at low applied voltage in vitro and in vivo

Lab on a Chip, 18(19), 2985–2993.

Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes

Biomaterials Science, 7(2), 669–682.

Targeted Treatment of Ischemic and Fibrotic Complications of Myocardial Infarction Using a Dual-Delivery Microgel Therapeutic

ACS Nano, 12(8), 7826–7837.

Targeted repair of heart injury by stem cells fused with platelet nanovesicles

Nature Biomedical Engineering, 2(1), 17–26.

Viscoelastic properties of microgel thin films control fibroblast modes of migration and pro-fibrotic responses

Biomaterials, 185, 371–382.