Annabel Meade

College of Sciences

Works (3)

Updated: July 2nd, 2024 05:12

2024 article

Evaluating the impact of anatomical and physiological variability on human equivalent doses using PBPK models

Schacht, C. M., Meade, A. E., Bernstein, A. S., Prasad, B., Schlosser, P. M., Tran, H. T., & Kapraun, D. F. (2024, May 25). TOXICOLOGICAL SCIENCES, Vol. 5.

By: C. Schacht*, A. Meade*, A. Bernstein *, B. Prasad*, P. Schlosser*, H. Tran n , D. Kapraun*

UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 22, 2024

2019 journal article

Estimation of probability distributions of parameters using aggregate population data: analysis of a CAR T-cell cancer model

MATHEMATICAL BIOSCIENCES AND ENGINEERING, 16(6), 7299–7326.

By: C. Schacht n, A. Meade n, H. Banks n, H. Enderling * & D. Abate-Daga *

author keywords: aggregate data; CAR T-cell therapy; cancer model; inverse problems; design of experiments
MeSH headings : Algorithms; Animals; Computer Simulation; Humans; Immunotherapy, Adoptive; Mice; Models, Theoretical; Neoplasm Transplantation; Neoplasms, Experimental / therapy; Population Dynamics; Probability; Receptors, Chimeric Antigen / chemistry; Reproducibility of Results; T-Lymphocytes / cytology
TL;DR: First elementary computations on the question how much data is needed for successful estimation of probability distributions are carried out on a class of CAR T-call cancer models in mice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 14, 2019

2019 journal article

Parameter estimation using aggregate data

APPLIED MATHEMATICS LETTERS, 100.

By: H. Banks*, A. Meade*, C. Schacht*, J. Catenacci*, W. Thompson *, D. Abate-Daga *, H. Enderling *

author keywords: Uncertainty quantification; Parameter estimation; CAR T cancer therapy
TL;DR: These issues are discussed in the context of a mathematical model to determine T-cell behavior with cancer chimeric antigen receptor (CAR) therapies where during the collection of data cancerous mice are sacrificed at each measurement time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: November 25, 2019

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