Works (7)

Updated: October 3rd, 2023 05:00

2023 journal article

FIOLA: an accelerated pipeline for fluorescence imaging online analysis

NATURE METHODS, 20(9), 1417-+.

By: C. Cai*, C. Dong*, J. Friedrich*, M. Rozsa*, E. Pnevmatikakis* & A. Giovannucci n

TL;DR: This work developed FIOLA, a framework for fluorescence imaging online analysis that extracts neuronal activity from calcium and voltage imaging movies at speeds one order of magnitude faster than state-of-the-art methods. (via Semantic Scholar)
Source: Web Of Science
Added: October 2, 2023

2022 article

A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution

Zhu, F., Grier, H. A., Tandon, R., Cai, C., Agarwal, A., Giovannucci, A., … Pandarinath, C. (2022, November 24). NATURE NEUROSCIENCE.

By: F. Zhu*, H. Grier*, R. Tandon*, C. Cai n, A. Agarwal, A. Giovannucci n, M. Kaufman*, C. Pandarinath*

MeSH headings : Animals; Mice; Brain; Calcium; Deep Learning; Diagnostic Imaging; Population Dynamics
TL;DR: RADICaL is described, a deep learning method that incorporates a novel network training strategy that capitalizes on the timing of 2p sampling to recover network dynamics with high temporal precision and infers network state more accurately than previous methods. (via Semantic Scholar)
Source: Web Of Science
Added: December 12, 2022

2022 journal article

Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy

CELL, 185(18), 3408-+.

By: Z. Liu*, X. Lu*, V. Villette*, Y. Gou*, K. Colbert*, S. Lai*, S. Guan*, M. Land* ...

MeSH headings : Animals; Interneurons; Mice; Microscopy / methods; Neurons / physiology; Photons; Wakefulness
TL;DR: JEDI-2P is identified, an indicator that is faster, brighter, and more sensitive and photostable than its predecessors and can report light-evoked responses in axonal termini of Drosophila interneurons and the dendrites and somata of amacrine cells of isolated mouse retina. (via Semantic Scholar)
Source: Web Of Science
Added: September 26, 2022

2022 review

Two-photon calcium imaging of neuronal activity

[Review of ]. NATURE REVIEWS METHODS PRIMERS, 2(1).

TL;DR: The experimental design and execution of two-photon calcium imaging is outlined, providing examples of ideal preparations and how data are analysed, and what the future of 2PCI might look like. (via Semantic Scholar)
Source: Web Of Science
Added: December 12, 2022

2021 journal article

Inhibitory gating of coincidence-dependent sensory binding in secondary auditory cortex

NATURE COMMUNICATIONS, 12(1).

By: A. Kline*, D. Aponte*, H. Tsukano*, A. Giovannucci* & H. Kato*

MeSH headings : Animals; Auditory Cortex / physiology; Auditory Perception / physiology; Evoked Potentials, Auditory / physiology; Female; Interneurons / physiology; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Parvalbumins / metabolism; Somatostatin / metabolism; Sound
TL;DR: A2 is proposed as a locus for multi-frequency integration, which may form the circuit basis for vocal processing, and the neural correlates in the mouse secondary auditory cortex underlying multifrequency binding in response to harmonic sounds are investigated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 16, 2021

2021 journal article

VolPy: Automated and scalable analysis pipelines for voltage imaging datasets

PLOS COMPUTATIONAL BIOLOGY, 17(4).

By: C. Cai n, J. Friedrich*, A. Singh*, M. Eybposh n, E. Pnevmatikakis*, K. Podgorski*, A. Giovannucci n

MeSH headings : Algorithms; Automation; Brain; Datasets as Topic; Electrophysiological Phenomena; Humans; Image Processing, Computer-Assisted / methods; Neuroimaging / methods; Neurons / physiology; Software
TL;DR: This work presents VolPy, an automated and scalable pipeline to pre-process voltage imaging datasets that features motion correction, memory mapping, automated segmentation, denoising and spike extraction built on a highly parallelizable, modular, and extensible framework optimized for memory and speed. (via Semantic Scholar)
Source: Web Of Science
Added: May 17, 2021

2020 journal article

Limbs Detection and Tracking of Head-Fixed Mice for Behavioral Phenotyping Using Motion Tubes and Deep Learning

IEEE ACCESS, 8, 37891–37901.

By: W. Abbas*, D. Masip* & A. Giovannucci n

author keywords: Tracking; Mice; Cameras; Electron tubes; Feature extraction; Training; Deep networks; motion detection; CNN; LSTM; optical flow; spatiotemporal; neuroscience; behavioral phenotyping
TL;DR: A deep learning-based image segmentation framework to automatically extract and label limb movements from movies capturing frontal and lateral views of head-fixed mice and introduces spatio-temporal coherence to the limb segmentation. (via Semantic Scholar)
Source: Web Of Science
Added: May 8, 2020

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