Works (4)
Updated: July 5th, 2023 14:21
2023 journal article
Scalable and High-Throughput In Vitro Vibratory Platform for Vocal Fold Tissue Engineering Applications
BIOENGINEERING-BASEL, 10(5).
author keywords: vocal fold; bioreactor; piezoelectric speaker; vibration; frequency; displacement; fibroblasts; mesenchymal stem cells; gene expression
TL;DR:
A scalable and high-throughput platform that mimics the mechanical microenvironment of the VFs in vitro and can incorporate commercial assay formats ranging from 6- to 96-well plates which represents a significant improvement in scalability.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 22, 2023
2022 article
Towards a standardized multi-tissue decellularization protocol for the derivation of extracellular matrix materials
Biehl, A., Martins, A. M. G. M., Davis, Z. G. G., Sze, D., Collins, L., Mora-Navarro, C., … Freytes, D. O. O. (2022, December 12). BIOMATERIALS SCIENCE, Vol. 12.
MeSH headings : Tissue Engineering / methods; Proteomics; Extracellular Matrix / chemistry; Hydrogels / chemistry; Biocompatible Materials / analysis; Tissue Scaffolds
TL;DR:
The present study is the first proof-of-concept towards the development of a standardized protocol that can be used to derive multiple ECM biomaterials via a previously established automated system and showed gelation and rheological properties consistent with previous ECM hydrogels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 3, 2023
2021 journal article
Bioreactors for Vocal Fold Tissue Engineering
TISSUE ENGINEERING PART B-REVIEWS, 28(1), 182–205.
author keywords: vocal fold; bioreactor; lamina propria; gene expression; fibrosis; inflammation
MeSH headings : Biocompatible Materials; Bioreactors; Cicatrix; Humans; Tissue Engineering / methods; Vocal Cords / pathology; Vocal Cords / physiology
TL;DR:
An in-depth analysis of VF bioreactor data to date reveals that mechanical stimulation significantly influences cell viability and the expression of pro-inflammatory and pro-fibrotic genes in vitro.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 29, 2021
2021 journal article
Microphysiological System for High-Throughput Computer Vision Measurement of Microtissue Contraction
ACS SENSORS, 6(3), 985–994.
author keywords: high throughput; 3D culture; tissue function; tissue contraction; computer vision
MeSH headings : Computers; Fibroblasts; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted
TL;DR:
An inexpensive, versatile, high-throughput platform to measure microtissue contraction in a 96-well plate configuration using one-step batch imaging and an algorithm uses pixel-based image analysis and computer vision techniques for the accurate multiwell quantification of positional changes in the optical microprobes caused by the contraction of the microtissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 10, 2021
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