Ankita Gupta

Neuroscience, Pain, Osteoarthritis, Animal Models, Translational Research

Works (6)

Updated: November 4th, 2024 18:20

2024 journal article

Emerging Evidence of Artemin/GFRα3 Signaling in Musculoskeletal Pain

Osteoarthritis and Cartilage.

By: A. Gupta* , S. Mishra & B. Lascelles

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: October 8, 2024

2023 article

Multi-Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing

Shih, Y.-R. V., Kingsley, D., Newman, H., Hoque, J., Gupta, A., Lascelles, B. D. X., & Varghese, S. (2023, November 8). ADVANCED SCIENCE, Vol. 11.

By: Y. Shih *, D. Kingsley *, H. Newman *, J. Hoque*, A. Gupta n , B. Lascelles  n, S. Varghese *

author keywords: adenosine; adenosine receptors; biomaterials; drug delivery; fracture healing; fracture pain; phenylboronic acids
TL;DR: The results demonstrate that local delivery of adenosine inhibited the nociceptive activity of peripheral neurons through activation of adenosine A1 receptor (ADORA1) and mitigated pain as demonstrated by weight bearing and open field movement tests. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 26, 2023

2022 journal article

Investigating the Role of Artemin and Its Cognate Receptor, GFR alpha 3, in Osteoarthritis Pain

FRONTIERS IN NEUROSCIENCE, 16.

By: L. Minnema n, A. Gupta n , S. Mishra n & B. Lascelles  n

author keywords: pain; osteoarthritis (OA); artemin; GFR alpha 3; TRPV1; monoiodoacetate (MIA)
TL;DR: The results provide a molecular basis of arthritis pain linked with artemin/GFRα3 signaling and indicate that further work is warranted to investigate the neuronal plasticity and the pathways that drive pain in OA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 28, 2022

2021 conference paper

Artemin and its cognate receptor, GFRΑ3, Play a function role in osteoarthritis pain

Osteoarthritis and Cartilage, 29, S372.

By: D. Lascelles*, L. Minnema n, A. Gupta n  & S. Mishra  n

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: June 10, 2022

2021 journal article

Serum artemin is not correlated with sensitivity within dogs with naturally occurring osteoarthritis pain

SCIENTIFIC REPORTS, 11(1).

By: A. Gupta n , L. Chiavaccini n, L. Minnema n, K. Chiu n, D. Knazovicky n , J. Hash n, S. Mishra n, B. Lascelles  n

MeSH headings : Animals; Arthralgia / diagnosis; Arthralgia / etiology; Dogs; Female; Male; Nerve Tissue Proteins / blood; Osteoarthritis / blood; Osteoarthritis / complications; Pain Threshold; Severity of Illness Index; Symptom Assessment
TL;DR: Serum ARTN was not associated with the degree of sensitization within dogs with OAP, and across dogs with varying OAP severity, there did not find any association between ARTN, and clinical measures of joint pain and disability, although a relationship between Artemin and joint pain was not ruled out. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 19, 2021

2018 journal article

Altered salt taste response and increased tongue epithelium Scnna1 expression in adult Engrailed-2 null mice

Physiology & Behavior.

Ankita Gupta

author keywords: Bitter; Sour; Saccharin; Epithelial sodium channel; Davis rig; Sweet
MeSH headings : Animals; Dose-Response Relationship, Drug; Epithelium / metabolism; Fructose / pharmacology; Gene Expression / genetics; Homeodomain Proteins / genetics; Homeodomain Proteins / physiology; Male; Mice; Mice, Knockout; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / physiology; Sodium Chloride / pharmacology; Sodium Glutamate / pharmacology; Taste / drug effects; Taste / physiology; Tongue / metabolism
TL;DR: Describing the taste function in En2-/- compared with En2+/+ in adult male mice indicates that deficits in En1 can produce sensory impairments that can have a measurable impact on taste, particularly salt taste. (via Semantic Scholar)
Source: ORCID
Added: June 10, 2022

Education

Updated: May 13th, 2023 11:34

2017 - present

North Carolina State University Raleigh, North Carolina, US
DVM/Ph.D. Candidate College of Veterinary Medicine

2013 - 2017

Rutgers University - Douglass Campus New Brunswick, NJ, US
BS Animal Science

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