@article{ardente_christian_borst_lewbart_2011, title={CLINICAL CHALLENGE}, volume={42}, ISSN={["1042-7260"]}, DOI={10.1638/2011-0028.1}, number={4}, journal={JOURNAL OF ZOO AND WILDLIFE MEDICINE}, author={Ardente, Amanda J. and Christian, Larry S. and Borst, Luke B. and Lewbart, Gregory A.}, year={2011}, month={Dec}, pages={770–773} } @article{ardente_chinnadurai_de voe_stringer_webb_ireland_saker_2011, title={Relationship between gastrointestinal transit time and anesthetic fasting protocols in the captive chimpanzee, Pan troglodytes}, volume={40}, ISSN={["1600-0684"]}, DOI={10.1111/j.1600-0684.2011.00468.x}, abstractNote={Background  Lengthy social separation and prolonged fasting time contribute to increased risks associated with anesthesia in captive primates. This study is an initial attempt to identify a safe pre‐anesthetic fasting procedure by identifying gastric emptying time (GET) and gastrointestinal transit time (GTT) of captive chimpanzees, Pan troglodytes.}, number={3}, journal={JOURNAL OF MEDICAL PRIMATOLOGY}, author={Ardente, A. and Chinnadurai, S. and De Voe, R. and Stringer, E. and Webb, T. and Ireland, J. and Saker, K.}, year={2011}, month={Jun}, pages={181–187} } @article{chinnadurai_devoe_koenig_gadsen_ardente_divers_2010, title={Comparison of an implantable telemetry device and an oscillometric monitor for measurement of blood pressure in anaesthetized and unrestrained green iguanas (Iguana iguana)}, volume={37}, ISSN={["1467-2987"]}, DOI={10.1111/j.1467-2995.2010.00557.x}, abstractNote={OBJECTIVE The objective of this study was to compare an implanted direct blood pressure monitor and a non-invasive oscillometric unit for use in anesthetized and awake green iguanas. STUDY DESIGN Prospective experimental trial. ANIMALS Four male and four female adult green iguanas (Iguana iguana) weighing 1833 +/- 534 g. METHODS For each animal, the carotid artery was surgically exposed and the catheter tip of the pressure transducer was placed in the aortic arch. Non-invasive blood pressure was measured using a cuff over the left femoral region. Pulse rate, respiratory rate and arterial blood pressure (ABP) measurements were taken every 5 minutes. Direct ABP measurements consisted of recording numerical values and graphic output. Simultaneous direct and indirect measurements were repeated in awake animals. RESULTS The oscillometric device failed to provide a reading in over 80% of attempts, and failed to provide readings that correlated with direct measurements. The implanted direct transducer was capable of detecting blood pressures throughout all ABP ranges examined. CONCLUSIONS The implantable transducer was a reliable means of determining blood pressure in this study, while the oscillometric device was unreliable and often failed to provide any reading. CLINICAL RELEVANCE We do not recommend using the oscillometric device as described in a research or clinical setting for green iguanas. The advantages of an implantable device include the ability to monitor awake and anesthetized subjects remotely and continuously. These monitors are small, biocompatible and function across a wide range of ABP.}, number={5}, journal={VETERINARY ANAESTHESIA AND ANALGESIA}, author={Chinnadurai, Sathya K. and DeVoe, Ryan and Koenig, Amie and Gadsen, Nadia and Ardente, Amanda and Divers, Stephen J.}, year={2010}, month={Sep}, pages={434–439} } @article{ardente_barlow_burns_goldman_baynes_2008, title={Vehicle effects on in vitro transdermal absorption of sevoflurane in the bullfrog, Rana catesbeiana}, volume={25}, ISSN={["1382-6689"]}, DOI={10.1016/j.etap.2007.12.001}, abstractNote={The experimental objectives were to identify a vehicle which produces a homogenous formulation when combined with the anesthetic solution sevoflurane and understand the dermal absorption of sevoflurane in silastic membranes and amphibian skin in vitro utilizing a flow-through diffusion system. Seven vehicles were evaluated in varying ratios with 5 formulations resulting in the desired homogenous consistency for practical application. Sevoflurane diffusion across silastic membranes was influenced by pluronic/lecithin organogel (PLO), pluronic F 127 20% gel, and sterile lube. Flux and permeability across silastic membranes were significantly greater in sterile lube than in the other formulations. While no significant vehicle effects were observed in bullfrog skin, the flux-time profiles suggest that sevoflurane diffusion in bullfrog skin may be positively influenced by PLO. Future in vivo studies are required to assess sevoflurane retention after removal of these formulations to more accurately control the plane of anesthesia in amphibians.}, number={3}, journal={ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY}, author={Ardente, Amanda J. and Barlow, Beth M. and Burns, Patrick and Goldman, Rebecca and Baynes, Ronald E.}, year={2008}, month={May}, pages={373–379} }