@article{roushan_kaur_karpusenko_countryman_ortiz_lim_wang_riehn_2014, title={Probing transient protein-mediated DNA linkages using nanoconfinement}, volume={8}, number={3}, journal={Biomicrofluidics}, author={Roushan, M. and Kaur, P. and Karpusenko, A. and Countryman, P. J. and Ortiz, C. P. and Lim, S. F. and Wang, H. and Riehn, R.}, year={2014} } @article{lim_karpusenko_blumers_streng_riehn_2013, title={Chromatin modification mapping in nanochannels}, volume={7}, number={6}, journal={Biomicrofluidics}, author={Lim, S. F. and Karpusenko, A. and Blumers, A. L. and Streng, D. E. and Riehn, R.}, year={2013} } @article{karpusenko_carpenter_zhou_lim_pan_riehn_2012, title={Fluctuation modes of nanoconfined DNA}, volume={111}, number={2}, journal={Journal of Applied Physics}, author={Karpusenko, A. and Carpenter, J. H. and Zhou, C. D. and Lim, S. F. and Pan, J. H. and Riehn, R.}, year={2012} } @article{lim_karpusenko_sakon_hook_lamar_riehn_2011, title={DNA methylation profiling in nanochannels}, volume={5}, number={3}, journal={Biomicrofluidics}, author={Lim, S. F. and Karpusenko, A. and Sakon, J. J. and Hook, J. A. and Lamar, T. A. and Riehn, R.}, year={2011} } @article{carpenter_karpusenko_pan_lim_riehn_2011, title={Density fluctuations dispersion relationship for a polymer confined to a nanotube}, volume={98}, number={25}, journal={Applied Physics Letters}, author={Carpenter, J. H. and Karpusenko, A. and Pan, J. H. and Lim, S. F. and Riehn, R.}, year={2011} } @article{streng_lim_pan_karpusenka_riehn_2009, title={Stretching chromatin through confinement}, volume={9}, ISSN={["1473-0189"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-70349311158&partnerID=MN8TOARS}, DOI={10.1039/b909217j}, abstractNote={We present a method for the stretching of chromatin molecules in nanofluidic channels width a cross-section of about 80 x 80 nm(2), and hundreds of microns long. The stretching of chromatin to about 12 basepairs/nm enables location-resolved optical investigation of the nucleic material with a resolution of up to 6 kbp. The stretching is based on the equilibrium elongation that polymers experience when they are introduced into nanofluidic channels that are narrower than the Flory coil corresponding to the whole chromatin molecule. We investigate whether the elongation of reconstituted chromatin can be described by the de Gennes model. We compare nanofluidic stretching of bare DNA and chromatin of equal genomic length, and find that chromatin is 2.5 times more compact in its stretched state.}, number={19}, journal={LAB ON A CHIP}, author={Streng, Diana E. and Lim, Shuang Fang and Pan, Junhan and Karpusenka, Alena and Riehn, Robert}, year={2009}, pages={2772–2774} }