Anuran Kumar Gayen
College of Sciences
Works (5)
Updated: July 5th, 2023 15:31
2020 journal article
An artificial pathway for polyketide biosynthesis
Nature Catalysis, 3(7), 536–538.
TL;DR:
Some of the inefficiencies and limitations of these systems have been solved by designing an artificial pathway for carbon–carbon bond formation via iterative rounds of non-decarboxylative thio-Claisen reactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 3, 2020
2020 article
Synthetic biology, combinatorial biosynthesis, and chemo-enzymatic synthesis of isoprenoids (September, 10.1007/s10295-020-02306-3, 2020)
Malico, A. A., Calzini, M. A., Gayen, A. K., & Williams, G. J. (2020, December). JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, Vol. 47, pp. 1181–1181.
TL;DR:
The article title was published incorrectly in the HTML version (online version only) of the online published article.
(via Semantic Scholar)
open access via link.springer.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 30, 2020
2020 journal article
Synthetic biology, combinatorial biosynthesis, and chemo‑enzymatic synthesis of isoprenoids
Journal of Industrial Microbiology & Biotechnology, 47(9-10), 675–702.
author keywords: Isoprenoids; Terpenes; Synthetic biology; Combinatorial biosynthesis; Hemiterpenes
MeSH headings : Biological Products; Hemiterpenes; Synthetic Biology; Terpenes / chemistry
TL;DR:
This review summarizes recent advances and strategies related to isoprenoid synthetic biology, combinatorial biosynthesis, and chemo-enzymatic synthesis, focusing on the past 5 years, as well as emerging applications of cell-free biosynthesis and high-throughput tools.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: September 21, 2020
2019 journal article
Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli
ACS Synthetic Biology, 8(6), 1391–1400.
MeSH headings : Biosensing Techniques / methods; Escherichia coli / genetics; Escherichia coli Proteins / genetics; Escherichia coli Proteins / isolation & purification; Escherichia coli Proteins / metabolism; Malonyl Coenzyme A / analysis; Malonyl Coenzyme A / metabolism; Metabolic Networks and Pathways; Polyketide Synthases / metabolism; Polyketides / metabolism; Protein Engineering / methods; Recombinant Proteins / genetics; Recombinant Proteins / isolation & purification; Recombinant Proteins / metabolism; Synthetic Biology; Transcription Factors / genetics; Transcription Factors / isolation & purification; Transcription Factors / metabolism
TL;DR:
The previously unknown broad effector promiscuity of FapR provides a platform to develop new tools and approaches that can be leveraged to overcome limitations of pathways that construct diverse α-carboxyacyl-CoAs and those that are dependent on them, including biofuels, antibiotics, anticancer drugs, and other value-added products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: July 15, 2019
2019 journal article
Synthesis and anticancer activities of proline-containing cyclic peptides and their linear analogs and congeners
SYNTHETIC COMMUNICATIONS, 49(2), 221–236.
author keywords: Anticancer activities; cell migration efficiency; cyclic peptides; linear peptides; Reniochalistatin
TL;DR:
A solution phase method was adopted for the synthesis of proline-containing cyclic pentapeptides 2 and total synthesis of naturally occurring cyclic heptapeptide Reniochalistatin B 3 and their linear analogs/congeners were evaluated for anti-cancer activity against HeLa cell line.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 18, 2019
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