Works (36)

Updated: April 11th, 2023 10:13

2022 journal article

Beneficial effects of eicosapentaenoic acid on the metabolic profile of obese female mice entails upregulation of HEPEs and increased abundance of enteric Akkermansia muciniphila

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1867(1).

By: A. Pal*, S. Sun*, M. Armstrong*, J. Manke*, N. Reisdorph*, V. Adams, A. Kennedy, Y. Zu* ...

author keywords: N-3 polyunsaturated fatty acids; bacteria; Microbial; Lipidomics
Sources: Web Of Science, ORCID
Added: November 8, 2021

2022 journal article

Prioritize biologically relevant ions for data-independent acquisition (BRI-DIA) in LC-MS/MS-based lipidomics analysis

METABOLOMICS, 18(8).

By: L. Duan, G. Scheidemantle, M. Lodge, M. Cummings n, E. Pham, X. Wang, A. Kennedy, X. Liu

Sources: Web Of Science, ORCID
Added: July 26, 2022

2020 journal article

CD8+ T cells regulate liver injury in obesity-related nonalcoholic fatty liver disease

American Journal of Physiology-Gastrointestinal and Liver Physiology, 318(2), G211–G224.

By: D. Breuer n, M. Pacheco*, M. Washington*, S. Montgomery*, A. Hasty* & A. Kennedy

author keywords: CD8(+) T cells; lymphocytes; nonalcoholic steatohepatitis; stellate cells
Sources: Crossref, ORCID
Added: January 20, 2020

2020 journal article

Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health

DIABETES, 69(3), 342–354.

By: X. Tong*, C. Dai*, J. Walker*, G. Nair*, A. Kennedy, R. Carr*, M. Hebrok*, A. Powers*, R. Stein*

Sources: Web Of Science, ORCID
Added: March 16, 2020

2018 journal article

Adipose Tissue is Enriched for Activated and Late-Differentiated CD8+ T Cells and Shows Distinct CD8+ Receptor Usage, Compared With Blood in HIV-Infected Persons

JAIDS Journal of Acquired Immune Deficiency Syndromes, 77(2), e14–e21.

By: J. Koethe*, W. McDonnell*, A. Kennedy, C. Abana*, M. Pilkinton*, I. Setliff*, I. Georgiev*, L. Barnett* ...

author keywords: HIV; obesity; metabolic disease; adipose tissue; T-cell receptor; clonality
Sources: Crossref, ORCID
Added: January 20, 2020

2018 journal article

Elevating adipose eosinophils in obese mice to physiologically normal levels does not rescue metabolic impairments

Molecular Metabolism, 8, 86–95.

By: W. Bolus*, K. Peterson*, M. Hubler*, A. Kennedy, M. Gruen* & A. Hasty*

author keywords: Inflammation; Obesity; Diabetes; Eosinophils; Interleukin 5; Adipose tissue
Sources: Web Of Science, ORCID
Added: November 22, 2020

2018 journal article

High CD8 T-Cell Receptor Clonality and Altered CDR3 Properties Are Associated With Elevated Isolevuglandins in Adipose Tissue During Diet-Induced Obesity

Diabetes, 67(11), 2361–2376.

By: W. McDonnell*, J. Koethe*, S. Mallal*, M. Pilkinton*, A. Kirabo*, M. Ameka*, M. Cottam*, A. Hasty*, A. Kennedy

Sources: Crossref, ORCID
Added: January 20, 2020

2018 journal article

MFehi adipose tissue macrophages compensate for tissue iron perturbations in mice

American Journal of Physiology-Cell Physiology, 315(3), C319–C329.

By: M. Hubler*, K. Erikson*, A. Kennedy & A. Hasty*

author keywords: adipose; homeostasis; iron; macrophage; polarization
Sources: Crossref, ORCID
Added: January 20, 2020

2018 journal article

Macrophage-Targeted Therapeutics for Metabolic Disease

Trends Pharmacological Sciences, 39, 536–546.

By: K. Peterson*, M. Cottam*, A. Kennedy & A. Hasty*

Sources: Web Of Science, ORCID
Added: January 20, 2020

2018 journal article

Obesity-induced reduction of adipose eosinophils is reversed with low-calorie dietary intervention

Physiological Reports, 6(22), e13919.

By: W. Bolus*, A. Kennedy & A. Hasty*

author keywords: Adipose tissue; eosinophils; inflammation; macrophages; obesity; weight loss
Sources: Crossref, ORCID
Added: January 20, 2020

2016 journal article

CC-chemokine receptor 7 (CCR7) deficiency alters adipose tissue leukocyte populations in mice

Physiological Reports, 4(18), e12971.

By: J. Orr*, A. Kennedy, A. Hill*, E. Anderson-Baucum*, M. Hubler* & A. Hasty*

author keywords: Adipose tissue; CCR7; macrophages; obesity; T cells
Sources: Crossref, ORCID
Added: January 20, 2020

2016 journal article

Role of lipids in the metabolism and activation of immune cells

The Journal of Nutritional Biochemistry, 34, 1–7.

By: M. Hubler* & A. Kennedy

author keywords: Inflammation; Macrophages; T lymphocytes; Oxysterols; Fatty acids
Sources: Crossref, ORCID
Added: January 20, 2020

2015 journal article

Activation of NF-κB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment

Molecular Metabolism, 4(10), 665–677.

By: A. Hill*, E. Anderson-Baucum*, A. Kennedy, C. Webb*, F. Yull* & A. Hasty*

author keywords: Adipose tissue; Macrophage; Apoptosis; Cleaved caspase-3; NF-kappa B; Survival
Sources: Crossref, ORCID
Added: January 20, 2020

2015 journal article

CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue

Journal of Leukocyte Biology, 98(4), 467–477.

By: W. Bolus*, D. Gutierrez*, A. Kennedy, E. Anderson-Baucum* & A. Hasty*

author keywords: inflammation; obesity; interleukin 5
Sources: Crossref, ORCID
Added: January 20, 2020

2013 journal article

Hyaluronan Accumulates With High-Fat Feeding and Contributes to Insulin Resistance

Diabetes, 62(6), 1888–1896.

By: L. Kang*, L. Lantier*, A. Kennedy, J. Bonner*, W. Mayes*, D. Bracy*, L. Bookbinder*, A. Hasty*, C. Thompson*, D. Wasserman*

Sources: Crossref, ORCID
Added: January 20, 2020

2013 journal article

Isolation of Adipose Tissue Immune Cells

Journal of Visualized Experiments, 5(75).

By: J. Orr*, A. Kennedy & A. Hasty*

author keywords: Immunology; Issue 75; Cellular Biology; Molecular Biology; Biophysics; Physiology; Anatomy; Biomedical Engineering; Surgery; Metabolic Diseases; Diabetes Mellitus; diabetes; Endocrine System Diseases; adipose tissue; AT; stromal vascular fraction; macrophage; lymphocyte; T cells; adipocyte; inflammation; obesity; cell; isolation; FACS; flow cytometry; mice; animal model
Sources: Crossref, ORCID
Added: January 20, 2020

2013 journal article

Loss of CCR5 results in glucose intolerance in diet-induced obese mice

American Journal of Physiology-Endocrinology and Metabolism, 305(7), E897–E906.

By: A. Kennedy, C. Webb*, A. Hill*, M. Gruen*, L. Jackson* & A. Hasty*

author keywords: C-C chemokine receptor 5; diet-induced obesity; macrophages; T cells; inflammation; insulin resistance; adipose tissue
Sources: Crossref, ORCID
Added: January 20, 2020

2013 journal article

Obesity Alters Adipose Tissue Macrophage Iron Content and Tissue Iron Distribution

Diabetes, 63(2), 421–432.

By: J. Orr*, A. Kennedy, E. Anderson-Baucum*, C. Webb*, S. Fordahl*, K. Erikson*, Y. Zhang*, A. Etzerodt*, S. Moestrup*, A. Hasty*

Sources: Crossref, ORCID
Added: January 20, 2020

2013 journal article

Weight Cycling Increases T-Cell Accumulation in Adipose Tissue and Impairs Systemic Glucose Tolerance

Diabetes, 62(9), 3180–3188.

By: E. Anderson*, D. Gutierrez*, A. Kennedy & A. Hasty*

Sources: Crossref, ORCID
Added: January 20, 2020

2012 journal article

Diacylglycerol kinase inhibitor R59022 attenuates conjugated linoleic acid-mediated inflammation in human adipocytes

Journal of Lipid Research, 54(3), 662–670.

By: K. Martinez*, S. Shyamasundar*, A. Kennedy, C. Chuang*, A. Marsh*, J. Kincaid*, T. Reid*, M. McIntosh*

author keywords: interleukins; intracellular calcium; lipogenic genes; delipidation
Sources: Crossref, ORCID
Added: January 20, 2020

2012 journal article

Impact of Macrophage Inflammatory Protein-1α Deficiency on Atherosclerotic Lesion Formation, Hepatic Steatosis, and Adipose Tissue Expansion

PLoS One, 7(2), e31508.

By: A. Kennedy, M. Gruen*, D. Gutierrez*, B. Surmi*, J. Orr*, C. Webb*, A. Hasty*

Sources: Web Of Science, ORCID
Added: November 22, 2020

2011 journal article

Aberrant Accumulation of Undifferentiated Myeloid Cells in the Adipose Tissue of CCR2-Deficient Mice Delays Improvements in Insulin Sensitivity

Diabetes, 60(11), 2820–2829.

By: D. Gutierrez*, A. Kennedy, J. Orr, E. Anderson, C. Webb, W. Gerrald, A. Hasty

Sources: Crossref, ORCID
Added: January 20, 2020

2011 journal article

Grape powder extract attenuates tumor necrosis factor α-mediated inflammation and insulin resistance in primary cultures of human adipocytes

The Journal of Nutritional Biochemistry, 22(1), 89–94.

By: C. Chuang*, A. Bumrungpert*, A. Kennedy, A. Overman*, T. West*, B. Dawson*, M. McIntosh*

author keywords: Grapes; Grape powder extract; Adipocytes; Inflammation; Insulin resistance
Sources: Crossref, ORCID
Added: January 20, 2020

2011 journal article

JNK Inhibition by SP600125 Attenuates trans-10, cis-12 Conjugated Linoleic Acid-Mediated Regulation of Inflammatory and Lipogenic Gene Expression

Lipids, 46(10), 885–892.

By: K. Martinez*, A. Kennedy & M. McIntosh*

author keywords: Conjugated linoleic acid; Adipocytes; JNK; cJun; Inflammation; Lipogenic genes
Sources: Crossref, ORCID
Added: January 20, 2020

2010 journal article

Antiobesity mechanisms of action of conjugated linoleic acid

The Journal of Nutritional Biochemistry, 21(3), 171–179.

By: A. Kennedy, K. Martinez, S. Schmidt, S. Mandrup, K. LaPoint & M. McIntosh

author keywords: CIA; Obesity; Adipose tissue; Energy metabolism; PPAR gamma; Adipogenesis; Inflammation
Sources: Crossref, ORCID
Added: January 20, 2020

2010 chapter

Conjugated Linoleic Acid

In Encyclopedia of Dietary Supplements, Second Edition (pp. 166–174).

By: K. Martinez, A. Kennedy & M. McIntosh

Sources: Crossref, ORCID
Added: January 20, 2020

2010 journal article

Inflammation and insulin resistance induced bytrans-10,cis-12 conjugated linoleic acid depend on intracellular calcium levels in primary cultures of human adipocytes

Journal of Lipid Research, 51(7), 1906–1917.

By: A. Kennedy, K. Martinez*, S. Chung*, K. LaPoint*, R. Hopkins*, S. Schmidt*, K. Andersen*, S. Mandrup*, M. McIntosh*

author keywords: cell signaling; fatty acid; reactive oxygen species
Sources: Crossref, ORCID
Added: January 20, 2020

2010 journal article

Mouse models of the metabolic syndrome

Disease Models & Mechanisms, 3(3-4), 156–166.

By: A. Kennedy, K. Ellacott*, V. King* & A. Hasty*

Sources: Crossref, ORCID
Added: January 20, 2020

2010 journal article

Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-α–mediated inflammation and insulin resistance in primary human adipocytes

The American Journal of Clinical Nutrition, 92(6), 1511–1521.

By: C. Chuang, K. Martinez, G. Xie, A. Kennedy, A. Bumrungpert, A. Overman, W. Jia, M. McIntosh

Sources: Crossref, ORCID
Added: January 20, 2020

2010 journal article

trans-10,cis-12-Conjugated Linoleic Acid Instigates Inflammation in Human Adipocytes Compared with Preadipocytes

Journal of Biological Chemistry, 285(23), 17701–17712.

By: K. Martinez*, A. Kennedy, T. West*, D. Milatovic*, M. Aschner* & M. McIntosh*

Sources: Crossref, ORCID
Added: January 20, 2020

2009 journal article

Xanthones from Mangosteen Prevent Lipopolysaccharide-Mediated Inflammation and Insulin Resistance in Primary Cultures of Human Adipocytes

The Journal of Nutrition, 139(6), 1185–1191.

By: A. Bumrungpert*, R. Kalpravidh*, C. Chitchumroonchokchai*, C. Chuang*, T. West*, A. Kennedy, M. McIntosh*

Sources: Crossref, ORCID
Added: January 20, 2020

2008 journal article

Conjugated linoleic acid-mediated inflammation and insulin resistance in human adipocytes are attenuated by resveratrol

Journal of Lipid Research, 50(2), 225–232.

By: A. Kennedy, A. Overman*, K. LaPoint*, R. Hopkins*, T. West*, C. Chuang*, K. Martinez*, D. Bell*, M. McIntosh*

author keywords: stress; anti-inflammatory; delipidation
Sources: Crossref, ORCID
Added: January 20, 2020

2008 journal article

Saturated Fatty Acid-Mediated Inflammation and Insulin Resistance in Adipose Tissue: Mechanisms of Action and Implications

The Journal of Nutrition, 139(1), 1–4.

By: A. Kennedy, K. Martinez*, C. Chuang*, K. LaPoint* & M. McIntosh

Sources: Crossref, ORCID
Added: January 20, 2020

2008 journal article

Trans-10, Cis-12 Conjugated Linoleic Acid Antagonizes Ligand-Dependent PPARγ Activity in Primary Cultures of Human Adipocytes

The Journal of Nutrition, 138(3), 455–461.

By: A. Kennedy, S. Chung*, K. LaPoint*, O. Fabiyi* & M. McIntosh*

Sources: Crossref, ORCID
Added: January 20, 2020

2006 journal article

Preadipocytes Mediate Lipopolysaccharide-Induced Inflammation and Insulin Resistance in Primary Cultures of Newly Differentiated Human Adipocytes

Endocrinology, 147(11), 5340–5351.

By: S. Chung*, K. LaPoint*, K. Martinez*, A. Kennedy, M. Boysen Sandberg & M. McIntosh*

Sources: Crossref, ORCID
Added: January 20, 2020

2004 journal article

The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter

Journal of Lipid Research, 45(7), 1197–1206.

By: L. Freeman*, A. Kennedy, J. Wu*, S. Bark*, A. Remaley*, S. Santamarina-Fojo*, H. Brewer*

author keywords: ATP binding cassette transporter; CPF; liver receptor homolog-1; FTF; FXR; SHP; sitosterolemia cholesterol; bile acids
Sources: Crossref, ORCID
Added: January 20, 2020