Works (8)

Updated: July 17th, 2023 09:00

2019 journal article

Mice-to-men comparison of inhaled drug-aerosol deposition and clearance

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 260, 82–94.

By: A. Kolanjiyil n, C. Kleinstreuer n, N. Kleinstreuer*, W. Pham* & R. Sadikot*

author keywords: Lung deposition; Mouse lung model; Human lung model; Dose extrapolation; Pharmacokinetics
MeSH headings : Administration, Inhalation; Aerosols / administration & dosage; Animals; Computer Simulation; Female; Humans; Hydrodynamics; Lung / anatomy & histology; Lung / physiology; Male; Mice; Models, Biological; Pulmonary Ventilation / physiology
Source: Web Of Science
Added: February 11, 2019

2019 journal article

Modeling Airflow and Particle Deposition in a Human Acinar Region

COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE, 2019.

By: A. Kolanjiyil n & C. Kleinstreuer n

MeSH headings : Acinar Cells / physiology; Computer Simulation; Humans; Imaging, Three-Dimensional; Models, Anatomic; Models, Biological; Particulate Matter / pharmacokinetics; Pulmonary Alveoli / anatomy & histology; Pulmonary Alveoli / physiology; Respiration; Respiratory Mechanics / physiology
Source: Web Of Science
Added: February 11, 2019

2018 journal article

Subject-variability effects on micron particle deposition in human nasal cavities

JOURNAL OF AEROSOL SCIENCE, 115, 12–28.

author keywords: Nasal cavities; Particle transport/deposition; Computational fluid-particle dynamics
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Computational analysis of aerosol-dynamics in a human whole-lung airway model

JOURNAL OF AEROSOL SCIENCE, 114, 301–316.

By: A. Kolanjiyil n & C. Kleinstreuer n

author keywords: Whole-lung airway model; Particle deposition; Lung air-particle dynamics; Local and total lung depositions; Actual breathing modes; Alveolar region
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Computationally efficient analysis of particle transport and deposition in a human whole-lung-airway model. Part I: Theory and model validation

COMPUTERS IN BIOLOGY AND MEDICINE, 79, 193–204.

By: A. Kolanjiyil n & C. Kleinstreuer n

author keywords: Lung; Airflow; Whole lung airway modeling; Computational fluid dynamics; Particle deposition
MeSH headings : Computational Biology; Computer Simulation; Humans; Hydrodynamics; Lung / physiology; Models, Biological; Respiratory Mechanics / physiology; Respiratory Transport / physiology; Trachea / physiology
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Laminar/turbulent airflow and microsphere deposition in a patient-specific airway geometry using an open-source solver

INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING AND TECHNOLOGY, 22(2), 145–161.

By: M. Vaish n, C. Kleinstreuer n, A. Kolanjiyil n, N. Saini n & N. Pillalamarri*

author keywords: OpenFOAM solver; patient-specific geometry and idealised configuration; modified eddy interaction model; microsphere transport and deposition; practical Stokes number range
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions-Part I: Whole-Lung Aerosol Dynamics

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 135(12).

By: A. Kolanjiyil n & C. Kleinstreuer n

author keywords: computational fluid-particle dynamics; multicompartment modeling; nanoparticle kinetics; nanoparticle deposition; toxic nanoparticles; nanodrugs
MeSH headings : Aerosols; Humans; Inhalation; Lung / metabolism; Lung / physiology; Models, Biological; Nanoparticles / chemistry; Particle Size; Pulmonary Alveoli / metabolism; Reproducibility of Results; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions-Part II: Multi-Compartmental Modeling

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 135(12).

By: A. Kolanjiyil n & C. Kleinstreuer n

author keywords: multicompartment modeling; animal test data; model validations; nanoparticle bio-kinetics; temporal accumulations; human organs
MeSH headings : Animals; Body Weight; Humans; Hydrodynamics; Inhalation; Lung / metabolism; Lung / physiology; Models, Biological; Nanoparticles; Organ Specificity; Rats; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018