Works (30)

2021 review

Postoperative Ileus: Comparative Pathophysiology and Future Therapies

[Review of ]. FRONTIERS IN VETERINARY SCIENCE.

By: E. Hellstrom, A. Ziegler & A. Blikslager

Sources: Web Of Science, ORCID
Added: October 12, 2021

2021 review

Probiotics, Prebiotics and Epithelial Tight Junctions: A Promising Approach to Modulate Intestinal Barrier Function

[Review of ]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(13), 6729.

By: E. Rose, J. Odle, A. Blikslager & A. Ziegler

Sources: ORCID, Web Of Science
Added: June 24, 2021

2020 article

A Glial Cell Inhibitor Blocks Epithelial Barrier Repair in a Pig Model of Intestinal Ischemia

Sheridan, A., Pridgen, T., Odle, J., Van Landeghem, L., Blikslager, A., & Ziegler, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: A. Sheridan, T. Pridgen, J. Odle, L. Van Landeghem, A. Blikslager & A. Ziegler

Source: Web Of Science
Added: October 12, 2020

2020 conference paper

A Glial Cell Inhibitor Blocks Epithelial Barrier Repair in a Pig Model of Intestinal Ischemia

Experimental Biology. San Diego, CA, USA.

By: A. Sheridan, T. Pridgen, J. Odle, L. Landeghem, A. Blikslager & A. Ziegler

Source: ORCID
Added: November 20, 2020

2020 conference paper

An age-dependent, rescuable defect in intestinal barrier repair is associated with an immature enteric glial network in a neonatal pig model of intestinal ischemia

Translational Science 2020. Washington, DC, USA.

By: A. Ziegler, A. Sheridan, T. Pridgen, J. Odle, L. Landeghem & A. Blikslager

Source: ORCID
Added: November 20, 2020

2020 article

Effects of Environmental Acclimation versus Transport Stress on Barrier Recovery in a Pig Model of Intestinal Ischemia and Repair

Ziegler, A., & Blikslager, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: A. Ziegler & A. Blikslager

Source: Web Of Science
Added: October 12, 2020

2020 conference paper

Effects of Environmental Acclimation versus Transport Stress on Barrier Recovery in a Pig Model of Intestinal Ischemia and Repair

Experimental Biology. San Diego, CA, USA.

By: A. Ziegler & A. Blikslager

Source: ORCID
Added: November 20, 2020

2020 article

Effects of Oligosaccharide Supplementation on Intestinal Morphology and Enteric Glial Cell Marker Expression in a Neonatal Pig Model

Shapiro, L., Ziegler, A., Odle, J., Van Landeghem, L., & Blikslager, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: L. Shapiro, A. Ziegler, J. Odle, L. Van Landeghem & A. Blikslager

Source: Web Of Science
Added: October 12, 2020

2020 conference paper

Effects of Oligosaccharide Supplementation on Intestinal Morphology and Enteric Glial Cell Marker Expression in a Neonatal Pig Model.

Experimental Biology. San Diego, CA, USA.

By: L. Shapiro, A. Ziegler, J. Odle, L. Landeghem & A. Blikslager

Source: ORCID
Added: November 20, 2020

2020 journal article

Environmental stressors affect intestinal permeability and repair responses in a pig intestinal ischemia model

TISSUE BARRIERS, 8(4), 1832421.

By: A. Ziegler, T. Pridgen & A. Blikslager

Sources: ORCID, Web Of Science
Added: October 27, 2020

2020 conference paper

Multi-institutional retrospective case-control study evaluating clinical outcomes of foals with small intestinal strangulating obstruction: 2000-2019.

2020 American College of Veterinary Surgeons Surgery E-Summit. American College of Veterinary Surgeons Surgery E-Summit.

By: S. Erwin, J. Dechant, M. Aitken, D. Hassel, A. Ziegler & A. Blikslager

Source: ORCID
Added: November 20, 2020

2020 journal article

Sparing the gut: COX ‐2 inhibitors herald a new era for treatment of horses with surgical colic

Equine Veterinary Education, 10.

By: A. Ziegler & A. Blikslager

Source: ORCID
Added: October 5, 2019

2020 article

iDISCO Allows Complete Visualization and Analysis of Postnatal Enteric Nervous System Development in a Comparative Pig Model

Erwin, S., Touvron, M., Odle, J., Van Landeghem, L., Blikslager, A., & Ziegler, A. (2020, April). FASEB JOURNAL, Vol. 34.

Source: Web Of Science
Added: October 12, 2020

2020 conference paper

iDISCO allows complete visualization and analysis of postnatal enteric nervous system development in a comparative pig model

Experimental Biology. San Diego, CA, USA.

By: S. Erwin, M. Touvron, J. Odle, L. Landeghem, A. Blikslager & A. Ziegler

Source: ORCID
Added: November 20, 2020

2019 journal article

Letter to the Editor: Bias in statistics or bias in equine veterinary medicine?

Equine Veterinary Journal, 51(3), 423–423.

By: A. Ziegler, C. Fogle, M. Burke & A. Blikslager

Sources: Web Of Science, ORCID, Crossref
Added: May 6, 2019

2019 journal article

Multicentre, blinded, randomised clinical trial comparing the use of flunixin meglumine with firocoxib in horses with small intestinal strangulating obstruction

EQUINE VETERINARY JOURNAL, 51(3), 329–335.

By: A. Ziegler, C. Freeman, C. Fogle, M. Burke, J. Davis, V. Cook, L. Southwood, A. Blikslager

Sources: Web Of Science, ORCID
Added: May 6, 2019

2019 conference paper

Rescue of Restitution Defect in a Neonatal Pig Intestinal Ischemia Model is associated with an Immature Enteric Glial Network

Digestive Disease Week. San Diego, CA, USA.

By: A. Ziegler, T. Pridgen, L. Landeghem, J. Odle, S. Magness & A. Blikslager

Source: ORCID
Added: November 20, 2020

2019 conference paper

Suckling piglets have a rescuable defect in intestinal barrier repair associated with an immature enteric glial network

Conference of Research Workers in Animal Disease. Chicago, IL, USA.

By: A. Ziegler, T. Pridgen, L. Landeghem, J. Odle, S. Magness & A. Blikslager

Source: ORCID
Added: November 20, 2020

2018 article

Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair

Ziegler, A. L., Pridgen, T. A., Mills, J. K., Gonzalez, L. M., Landeghem, L. V., Odle, J., & Blikslager, A. T. (2018, July 3). (Vol. 7). Vol. 7.

By: A. Ziegler, T. Pridgen, J. Mills, L. Gonzalez, L. Landeghem, J. Odle, A. Blikslager

Source: ORCID
Added: September 9, 2019

2018 journal article

Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair

PLOS ONE, 13(8), e0200674.

By: A. Ziegler, T. Pridgen, J. Mills, L. Gonzalez, L. Landeghem, J. Odle, A. Blikslager

Ed(s): J. Karhausen

Source: ORCID
Added: September 9, 2019

2018 conference paper

Neonatal Defect in Subacute Barrier Repair is Rescued by Juvenile Mucosal Homogenate in a Pig Model of Intestinal Ischemia and Repair

National Veterinary Scholars Symposium, Aug 3. College Station, TX, USA.

By: A. Ziegler, T. Pridgen, L. Landeghem, L. Gonzalez, J. Odle & A. Blikslager

Source: ORCID
Added: November 20, 2020

2018 conference paper

Randomized control trial comparing flunixin meglumine and firocoxib in equine strangulating obstruction

American Association of Equine Practitioners Convention. Oral Abstract: American Association of Equine Practitioners.

By: A. Ziegler, C. Freeman, C. Fogle, M. Burke, J. Davis, L. Southwood, V. Cook, A. Blikslager

Source: ORCID
Added: November 20, 2020

2017 conference paper

Neonates have a reduced ability to repair jejunal mucosal injury as compared to weanlings in a porcine model of small intestinal strangulating obstruction

12th International Colic Research Symposium. Lexington, KY, USA.

By: A. Ziegler, T. Pridgen, L. Landeghem, L. Gonzalez, J. Odle & A. Blikslager

Source: ORCID
Added: November 20, 2020

2017 conference paper

Neonates have reduced epithelial wound healing associated with fewer enteric glial cells as compared to juveniles in a pig model of intestinal ischemic injury and repair

FASEB Gastrointestinal Tract XVII. CO, USA.

By: A. Ziegler, T. Pridgen, L. Landeghem, L. Gonzalez, J. Odle & A. Blikslager

Source: ORCID
Added: November 20, 2020

2017 conference paper

Randomized control trial comparing flunixin and firocoxib in equine strangulating obstruction

12th International Colic Research Symposium. Lexington, KY, USA.

By: A. Ziegler, C. Fogle, M. Burke, J. Davis, L. Southwood, V. Cook, A. Blikslager

Source: ORCID
Added: November 20, 2020

2017 article

Update on the use of cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs in horses

Journal of the American Veterinary Medical Association, Vol. 250, pp. 1271–1274.

By: A. Ziegler, C. Fogle & A. Blikslager

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Large Animal Models: The Key to Translational Discovery in Digestive Disease Research

Cellular and Molecular Gastroenterology and Hepatology, 2(6), 716–724.

By: A. Ziegler, L. Gonzalez & A. Blikslager

Source: ORCID
Added: September 9, 2019

2016 conference paper

Neonates Have a Reduced Ability to Repair Jejunal Mucosal Injury as Compared to Juveniles in a Pig Model of Ischemia/ Reperfusion Injury

Digestive Disease Week. San Diego, CA, USA.

By: A. Ziegler, T. Pridgen, G. Carnighan, J. Odle, L. Gonzalez & A. Blikslager

Source: ORCID
Added: November 20, 2020

2015 journal article

Expression of WNT5A in Idiopathic Pulmonary Fibrosis and Its Control by TGF-β and WNT7B in Human Lung Fibroblasts

Journal of Histochemistry & Cytochemistry, 64(2), 99–111.

By: D. Newman, W. Sills, K. Hanrahan, A. Ziegler, K. Tidd, E. Cook, P. Sannes

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2013 conference paper

Porcine alveolar type II cells as a potential model for human alveolar epithelium in culture.

National Veterinary Scholars Symposium. Lansing, MI, USA.

By: A. Welch, D. Newman & P. Sannes

Source: ORCID
Added: November 20, 2020

Employment

2019 - present

North Carolina State University Ralaigh, NC, US
Research Assistant Professor Clinical Sciences

2017 - 2019

University of North Carolina Chapel Hill, NC, US
Postdoctoral Trainee Medicine

Education

2017 - 2019

University of North Carolina Chapel Hill, NC, US
Postdoctoral Fellowship; Basic Science Gastroenterology Medicine

2015 - 2018

North Carolina State University Raleigh, NC, US
Doctorate of Philosophy Comparative Biomedical Sciences

2011 - 2015

North Carolina State University Raleigh, NC, US
Doctor of Veterinary Medicine

2008 - 2011

University of Delaware Newark, DE, US
B.S. Pre-veterinary Medicine and Animal Biosciences

Funding History

Funding history based on the linked ORCID record.

contract November 1, 2019 - October 1, 2021
Postnatal Development of Intestinal Barrier Repair
National Institutes of Health Office of Research Infrastructure Programs
grant August 15, 2019 - July 31, 2024
Postnatal development of intestinal barrier repair
Office of the Director
grant August 15, 2019 - June 30, 2024
Post-natal development of enteric glial cell-epithelial interactions in repair of ischemic-injured intestine
National Institute of Child Health and Human Development
grant April 1, 2019 - March 31, 2022
Bioactive nutrients enhance intestinal neural networks and rescue mucosal repair in developing neonates
National Institute of Food and Agriculture
grant August 1, 2017 - May 1, 2018
Characterization of glial cells network development and mechanisms of glial cell-mediated mucosal repair in a neonatal pig model of intestinal ischemia
North Carolina State University
grant July 1, 2017 - June 30, 2019
Gastroenterology Research Training
National Institute of Diabetes and Digestive and Kidney Diseases
grant July 1, 2017 - May 1, 2018
Mechanisms of glial-mediated mucosal barrier repair in a neonatal pig model of intestinal ischemia
College of Veterinary Medicine, North Carolina State University
salary-award January 1 - December 1, 2016
Randomized control trial comparing flunixin and firocoxib in equine strangulating obstruction
Grayson-Jockey Club Research Foundation
grant September 1, 1985 - November 30, 2024
Center for Gastrointestinal Biology and Disease
National Institute of Diabetes and Digestive and Kidney Diseases