Aiden Jones

Works (2)

Updated: July 5th, 2023 15:30

2020 journal article

Systematic Profiling of Full-Length Ig and TCR Repertoire Diversity in Rhesus Macaque through Long Read Transcriptome Sequencing

JOURNAL OF IMMUNOLOGY, 204(12), 3434–3444.

By: H. Brochu n , E. Tseng *, E. Smith*, M. Thomas *, A. Jones n, K. Diveley n, L. Law *, S. Hansen * ...

MeSH headings : Animals; High-Throughput Nucleotide Sequencing / methods; Humans; Immunoglobulins / genetics; Immunoglobulins / immunology; Macaca mulatta / genetics; Macaca mulatta / immunology; Receptors, Antigen, T-Cell / immunology; Transcriptome / genetics; Transcriptome / immunology
TL;DR: New rhesus-specific assays are designed that remove the need for primers conventionally targeting variable regions and allow single cell level Ig and TCR repertoire analysis, and the first complete reference set for the constant regions of all known isotypes and chain types of rhesu Ig andTCR repertoires is constructed. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: July 6, 2020

2019 journal article

Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis

MICROBIAL CELL, 6(3), 177–183.

By: . Catherine M. O'Connell *, H. Brochu n , J. Girardi *, E. Harrell n, A. Jones n, T. Darville *, A. Sena *, X. Peng n 

author keywords: RNA-seq; chlamydia; gonorrhea; natural infection; microbiome
TL;DR: It is suggested that total RNA profiling will advance understanding of the interplay of pathogen, host and microbiota during natural infection and may reveal novel, outcome-relevant biomarkers. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: March 18, 2019

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