Alejandra Mondino Vero

Works (13)

Updated: December 13th, 2024 05:01

2024 journal article

A randomized, controlled clinical trial demonstrates improved owner-assessed cognitive function in senior dogs receiving a senolytic and NAD plus precursor combination

SCIENTIFIC REPORTS, 14(1).

By: K. Simon n, K. Russell n, A. Mondino  n, C. Yang n, B. Case n, Z. Anderson n, C. Whitley n, E. Griffith n , M. Gruen n , N. Olby n 

author keywords: Aging; Senolytic; NAD plus; Canine cognitive dysfunction syndrome; Cognitive impairment; Longevity
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Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024

2024 article

Characterising the power spectrum dynamics of the non-REM to REM sleep transition

Serantes, D., Cavelli, M., Gonzalez, J., Mondino, A., Benedetto, L., & Torterolo, P. (2024, November 9). JOURNAL OF SLEEP RESEARCH.

By: D. Serantes *, M. Cavelli *, J. Gonzalez *, A. Mondino  n, L. Benedetto * & P. Torterolo *

author keywords: EEG; intermediate stage; REM sleep; sleep spindles; slow wave sleep
Source: Web Of Science
Added: November 25, 2024

2024 journal article

Cross-sectional and longitudinal analysis of health-related quality of life (HRQoL) in senior and geriatric dogs

PLOS ONE, 19(9).

By: A. Mondino  n, C. Yang n, K. Simon n, G. Fefer n, J. Robertson n , M. Gruen n , N. Olby n 

Ed(s): J. Suchodolski

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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 8, 2024

2024 journal article

Establishing a clinically applicable frailty phenotype screening tool for aging dogs

FRONTIERS IN VETERINARY SCIENCE, 11.

By: K. Russell n, A. Mondino  n, G. Fefer n, E. Griffith n , K. Saker n, M. Gruen n , N. Olby n 

author keywords: frailty; canine frailty; frailty phenotype; geriatric; aging dogs
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 21, 2024

2023 journal article

A novel task of canine olfaction for use in adult and senior pet dogs

SCIENTIFIC REPORTS, 13(1).

By: M. Khan n, A. Mondino  n, K. Russell n, B. Case n, G. Fefer n, H. Woods n, N. Olby n , M. Gruen n 

MeSH headings : Dogs; Animals; Smell; Food; Aging; Neuropsychological Tests
TL;DR: A novel olfaction test using spontaneous search behavior in dogs to find a hidden food treat in a three-choice task with both light-phase and dark-phase conditions is described, making it feasible to compare between and within groups of pet dogs. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 19, 2023

2023 article

Age-associated changes in electroretinography measures in companion dogs

Salzman, M. M., Merten, N., Panek, W. K., Fefer, G., Mondino, A., Westermeyer, H. D., … Mowat, F. M. (2023, June 11). DOCUMENTA OPHTHALMOLOGICA, Vol. 6.

By: M. Salzman *, N. Merten *, W. Panek n , G. Fefer n, A. Mondino  n, H. Westermeyer n , M. Gruen n , N. Olby n , F. Mowat n

author keywords: Translational model; Aging; Retina; ERG; Canine; Anxiolytic
TL;DR: Consideration of anxiolytic medication use should be made when conducting ERG studies in dogs, as aged companion dogs have slower and reduced amplitude responses in both rod- and cone-mediated ERG. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 19, 2023

2023 journal article

Development and validation of a sleep questionnaire, SNoRE 3.0, to evaluate sleep in companion dogs

SCIENTIFIC REPORTS, 13(1).

By: A. Mondino  n, C. Ludwig n, C. Menchaca n, K. Russell n, K. Simon n, E. Griffith n , A. Kis *, B. Lascelles  n, M. Gruen n , N. Olby n 

TL;DR: A valid and reliable questionnaire tool is described, that can be used as a cost-effective way to monitor dog sleep in clinical settings. (via Semantic Scholar)
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8. Decent Work and Economic Growth (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 23, 2023

2023 journal article

Relationship between engagement with the impossible task, cognitive testing, and cognitive questionnaires in a population of aging dogs

FRONTIERS IN VETERINARY SCIENCE, 9.

By: M. Khan n, A. Mondino  n, K. Russell n, B. Case n, G. Fefer n, H. Woods n, N. Olby n , M. Gruen n 

author keywords: canine cognitive dysfunction syndrome; canine cognition; frustration; aging; dogs
TL;DR: The high correlation with several cognitive measures and the ease of administration of this test makes it a useful tool in evaluating canine cognitive dysfunction syndrome, however it is unclear if increased frustration or other cognitive processes are contributing to the observed changes. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 6, 2023

2023 journal article

Sleep and cognition in aging dogs. A polysomnographic study

FRONTIERS IN VETERINARY SCIENCE, 10.

By: A. Mondino  n, M. Catanzariti*, D. Mateos *, M. Khan n, C. Ludwig n, A. Kis *, M. Gruen n , N. Olby n 

author keywords: NREM sleep; REM sleep; canine cognitive dysfunction syndrome; quantitative EEG; power spectrum; coherence; complexity
TL;DR: Polysomnographic recordings in dogs can detect sleep-wakefulness cycle changes associated with dementia, and their potential clinical use to monitor the progression of canine cognitive dysfunction syndrome is evaluated. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: May 22, 2023

2023 journal article

Winning the race with aging: age-related changes in gait speed and its association with cognitive performance in dogs

FRONTIERS IN VETERINARY SCIENCE, 10.

By: A. Mondino  n, M. Khan n, B. Case n, G. Fefer n, W. Panek n , M. Gruen n , N. Olby n 

author keywords: canine cognitive dysfunction syndrome; canine gerontology; mobility; walking speed; memory; attention
TL;DR: Dogs' food-motivated gait speed off leash is correlated with fractional lifespan and cognitive performance in dogs, particularly in the domains of attention and working memory and proves to be a more effective indicator of age-related deterioration and cognitive decline than gaitspeed on leash. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: July 24, 2023

2022 journal article

Electroencephalographic signatures of dogs with presumptive diagnosis of canine cognitive dysfunction

RESEARCH IN VETERINARY SCIENCE, 150, 36–43.

By: A. Mondino  n, M. Gutierrez, C. Gonzalez, D. Mateos *, P. Torterolo *, N. Olby n , L. Delucchi

author keywords: Aging; Alzheimer'sdisease; Onehealth; Cognition
MeSH headings : Animals; Cognition Disorders / diagnosis; Cognition Disorders / psychology; Cognitive Dysfunction / diagnosis; Dog Diseases / diagnosis; Dogs; Electroencephalography / veterinary; Humans; Neurodegenerative Diseases / veterinary; Quality of Life
TL;DR: It is demonstrated that quantitative EEG analysis could aid the diagnosis of CCD, and reinforce the CCD as a translational model of early AD. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 15, 2022

2022 journal article

Low frequency oscillations drive EEG's complexity changes during wakefulness and sleep

NEUROSCIENCE, 494, 1–11.

By: J. Gonzalez *, D. Mateos *, M. Cavelli *, A. Mondino  n, C. Pascovich *, P. Torterolo *, N. Rubido *

author keywords: EEG; sleep-wake cycle; low frequency oscillations
MeSH headings : Animals; Electroencephalography; Neocortex; Rats; Sleep / physiology; Sleep, REM / physiology; Wakefulness / physiology
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Source: Web Of Science
Added: June 27, 2022

2022 journal article

Static posturography as a novel measure of the effects of aging on postural control in dogs

PLOS ONE, 17(7).

By: A. Mondino  n, G. Wagner n, K. Russell n, E. Lobaton n , E. Griffith n , M. Gruen n , B. Lascelles  n, N. Olby n 

Ed(s): R. Evans

MeSH headings : Acceleration; Aging; Animals; Arthralgia; Dogs; Postural Balance; Reproducibility of Results
TL;DR: It is found that pressure sensitive walkway systems are a reliable tool to evaluate postural sway in dogs; and that postural swayed is affected by morphometric parameters and increases with age and joint pain. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 12, 2022

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