Anne Marion Taylor

Works (6)

Updated: July 5th, 2023 15:40

2019 journal article

Multi-compartment Microfluidic Device Geometry and Covalently Bound Poly-D-Lysine Influence Neuronal Maturation

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 7.

By: J. Kamande*, T. Nagendran*, J. Harris* & A. Taylor*

author keywords: neuron; human stem cells; standard neuron device; multi-compartment devices; microfluidic chambers; silicone chambers; glutamatergic neurons; compartmentalized microfluidic platform
TL;DR: It is found that covalently bound PDL greatly improved the differentiation and maturation of stem cell-derived neurons within the devices, and experimental paradigms using the multi-compartment platform show that axons of human stem cell derived neurons intrinsically regenerate in the absence of inhibitory cues. (via Semantic Scholar)
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Source: Web Of Science
Added: April 20, 2020

2019 journal article

Unique Axon-to-Soma Signaling Pathways Mediate Dendritic Spine Loss and Hyper-Excitability Post-axotomy

FRONTIERS IN CELLULAR NEUROSCIENCE, 13.

By: T. Nagendran* & A. Taylor*

author keywords: retrograde signaling; axon-to-soma; injury model; axotomy; dendritic spine loss; hyper-excitability
TL;DR: It is found that calcium release from axonal ER is critical for the induction of hyper-excitability and inhibition loss, and suggests that synapse loss and hyper-Excitability are uncoupled responses following axon injury. (via Semantic Scholar)
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Source: Web Of Science
Added: October 7, 2019

2016 journal article

The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates

Journal of Cell Biology, 212(7), 789–801.

By: M. Pinto, P. Alves, L. Martins, J. Pedro, H. Ryu, N. Jeon, A. Taylor, R. Almeida

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Magnetic Alignment of Microelements Containing Cultured Neuronal Networks for High-Throughput Screening

JOURNAL OF BIOMOLECULAR SCREENING, 20(9), 1091–1100.

By: K. Gordon n, Y. Wang *, N. Allbritton n & A. Taylor n

author keywords: high-throughput screening; primary neurons; magnetic centering; microfabrication; finite element analysis; microraft arrays
MeSH headings : Animals; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; High-Throughput Screening Assays / instrumentation; High-Throughput Screening Assays / methods; Magnetic Phenomena; Nerve Net / cytology; Neurons / drug effects; Neurons / physiology; Rats, Sprague-Dawley
TL;DR: A magnet array plate is developed, compatible with HTS fluid-handling systems, to center microrafts within wells, finding a centering efficiency of 100%, compared with 4.35% using a flat magnet, and concluding that micRORafts could be centered after settling randomly within the well, overcoming friction. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2015 journal article

The E3 ubiquitin ligase TRIM9 Is a filopodia off switch required for netrin-dependent axon guidance

Developmental Cell, 35(6), 698–712.

By: S. Menon, N. Boyer, C. Winkle, L. McClain, C. Hanlin, D. Pandey, S. Rothenfusser, A. Taylor, S. Gupton

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Axonal translation of beta-catenin regulates synaptic vesicle dynamics

Journal of Neuroscience, 33(13), 5584–5589.

By: A. Taylor, J. Wu, H. Tai & E. Schuman

Source: NC State University Libraries
Added: August 6, 2018

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