@inproceedings{ankeny_adkins_o’neill_2022, title={Impact of Two Reflective Practices in an Engineering Laboratory Course using Standards-based Grading}, author={Ankeny, C.J. and Adkins, A.N. and O’Neill, D.P.}, year={2022}, month={Jun} }
 @article{adkins_fong_dewald_murray_2022, title={Variability of in vivo Sarcomere Length Measures in the Upper Limb Obtained With Second Harmonic Generation Microendoscopy}, volume={12}, DOI={10.3389/fphys.2021.817334}, abstractNote={The lengths of a muscle’s sarcomeres are a primary determinant of its ability to contract and produce force. In addition, sarcomere length is a critical parameter that is required to make meaningful comparisons of both the force-generating and excursion capacities of different muscles. Until recently, in vivo sarcomere length data have been limited to invasive or intraoperative measurement techniques. With the advent of second harmonic generation microendoscopy, minimally invasive measures of sarcomere length can be made for the first time. This imaging technique expands our ability to study muscle adaptation due to changes in stimulus, use, or disease. However, due to past inability to measure sarcomeres outside of surgery or biopsy, little is known about the natural, anatomical variability in sarcomere length in living human subjects. To develop robust experimental protocols that ensure data provide accurate representations of a muscle’s sarcomere lengths, we sought to quantify experimental uncertainty associated with in vivo measures of sarcomere lengths. Specifically, we assessed the variability in sarcomere length measured (1) within a single image, along a muscle fiber, (2) across images captured within a single trial, across trials, and across days, as well as (3) across locations in the muscle using second harmonic generation in two upper limb muscles with different muscle architectures, functions, and sizes. Across all of our measures of variability we estimate that the magnitude of the uncertainty for in vivo sarcomere length is on the order of ∼0.25 μm. In the two upper limb muscles studied we found larger variability in sarcomere lengths within a single insertion than across locations. We also developed custom code to make measures of sarcomere length variability across a single fiber and determined that this codes’ accuracy is an order of magnitude smaller than our measurement uncertainty due to sarcomere variability. Together, our findings provide guidance for the development of robust experimental design and analysis of in vivo sarcomere lengths in the upper limb.}, journal={Frontiers in Physiology}, author={Adkins, A.N. and Fong, Rm and Dewald, Jpa and Murray, W.M.}, year={2022} }
 @article{adkins_dewald_garmirian_nelson_murray_2021, title={Serial sarcomere number is substantially decreased within the paretic biceps brachii in individuals with chronic hemiparetic stroke}, volume={118}, url={https://doi.org/10.1073/pnas.2008597118}, DOI={10.1073/pnas.2008597118}, abstractNote={Significance}, number={26}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Adkins, Amy N. and Dewald, Julius P. A. and Garmirian, Lindsay P. and Nelson, Christa M. and Murray, Wendy M.}, year={2021}, month={Jun} }
 @article{adkins_fong_dewald_murray_2021, title={Variability of in vivo sarcomere length measures in the upper limb obtained with second harmonic generation microendoscopy}, volume={11}, url={https://doi.org/10.1101/2021.11.17.468984}, DOI={10.1101/2021.11.17.468984}, abstractNote={Abstract}, publisher={Cold Spring Harbor Laboratory}, author={Adkins, Amy N and Fong, Ryan and Dewald, Julius P A and Murray, Wendy M}, year={2021}, month={Nov} }
 @inproceedings{adkins_o'neill_ankeny_2021, title={Work-in-Progress: Effectiveness of different reflection approaches for improving mastery in an engineering laboratory course}, author={Adkins, A.N. and O'Neill, D.P. and Ankeny, C.J.}, year={2021}, month={Jun} }
 @article{adkins_murray_2020, title={Obtaining Quality Extended Field-of-View Ultrasound Images of Skeletal Muscle to Measure Muscle Fascicle Length}, volume={166}, DOI={10.3791/61765}, abstractNote={Muscle fascicle length, which is commonly measured in vivo using traditional ultrasound, is an important parameter defining a muscle's force generating capacity. However, over 90% of all upper limb muscles and 85% of all lower limb muscles have optimal fascicle lengths longer than the field-of-view of common traditional ultrasound (T-US) probes. A newer, less frequently adopted method called extended field-of-view ultrasound (EFOV-US) can enable direct measurement of fascicles longer than the field-of-view of a single T-US image. This method, which automatically fits together a sequence of T-US images from a dynamic scan, has been demonstrated to be valid and reliable for obtaining muscle fascicle lengths in vivo. Despite the numerous skeletal muscles with long fascicles and the validity of the EFOV-US method for making measurements of such fascicles, few published studies have utilized this method. In this study, we demonstrate both how to implement the EFOV-US method to obtain high quality musculoskeletal images and how to quantify fascicle lengths from those images. We expect that this demonstration will encourage the use of the EFOV-US method to increase the pool of muscles, both in healthy and impaired populations, for which we have in vivo muscle fascicle length data.}, journal={Journal of Visualized Experiments}, author={Adkins, A.N. and Murray, W.M.}, year={2020}, month={Dec}, pages={e61765} }
 @inproceedings{adkins_o'neill_ankeny_2020, title={Work-in-Progress: Effectiveness of different reflection approaches for improving mastery in an engineering laboratory course}, author={Adkins, A.N. and O'Neill, D.P. and Ankeny, C.J.}, year={2020}, month={Jun} }
 @inproceedings{adkins_dewald_murray_2019, title={Quantifying in vivo variability in sarcomere length along the long head of the biceps brachii}, author={Adkins, A.N. and Dewald, J.P.A. and Murray, W.M.}, year={2019}, month={Jul} }
 @inproceedings{adkins_garmirian_nelson_dewald_murray_2019, title={The paretic biceps brachii contains fewer sarcomeres in series than the contralateral biceps brachii following stroke}, author={Adkins, A.N. and Garmirian, L. and Nelson, C.M. and Dewald, J.P.A. and Murray, W.M.}, year={2019}, month={Jul} }
 @inproceedings{adkins_garmirian_nelson_dewald_murray_2018, title={Characterizing Multiscale in vivo Muscle Architecture Changes Following Stroke}, author={Adkins, A.N. and Garmirian, L. and Nelson, C.M. and Dewald, J.P.A. and Murray, W.M.}, year={2018}, month={Aug} }
 @inproceedings{adkins_garmirian_nelson_dewald_murray_2018, title={Early evidence for a decrease in biceps optimal fascicle length based on in vivo muscle architecture measures in individuals with chronic hemiparetic stroke}, author={Adkins, A.N. and Garmirian, L. and Nelson, C.M. and Dewald, J.P.A. and Murray, W.M.}, year={2018}, month={Nov} }
 @inproceedings{adkins_garmirian_nelson_dewald_murray_2018, title={Measuring In Vivo Muscle Architecture Parameters to Determine Changes in Optimal Fascicle Length and Physiological Cross Sectional Area Following Hemiparetic Stroke: Preliminary Findings}, author={Adkins, A.N. and Garmirian, L. and Nelson, C.M. and Dewald, J.P.A. and Murray, W.M.}, year={2018}, month={Jun} }
 @article{jarque-bou_adkins_darhbe_gracia-ibañez_murray_vergara_sancho-bru_2018, title={O 075 – Exploration of the role of forearm muscles during activities of daily living}, volume={65}, url={https://doi.org/10.1016/j.gaitpost.2018.06.102}, DOI={10.1016/j.gaitpost.2018.06.102}, abstractNote={Instrumented gloves are motion capture systems that are widely used due to the simplicity of the setup required and the absence of occlusion problems when manipulating objects. Nevertheless, the effect of their use on manipulation capabilities has not been studied to date. Therefore, the aim of this work is to quantify the effect of wearing CyberGlove instrumented gloves on these capabilities when different levels of precision are required. Thirty healthy subjects were asked to perform three standardised dexterity tests twice: bare-handed and wearing instrumented gloves. The tests were the Sollerman Hand Function Test (to evaluate capability of performing activities of daily living), the Box and Block Test (to evaluate gross motor skills) and the Purdue Pegboard Test (to evaluate fine motor skills). Scores obtained in the test evaluating fine motor skills decreased by an average of 29% when wearing gloves, while scores obtained on those evaluating gross motor skills and capability to perform activities of daily living were reduced by an average of 8% and 3%, respectively. The use of instrumented gloves to record hand kinematics is only recommended when performing tasks requiring medium and gross motor skills.}, journal={Gait and Posture}, author={Jarque-Bou, N. and Adkins, A.N. and Darhbe, V. and Gracia-Ibañez, V. and Murray, W. and Vergara, M. and Sancho-Bru, J.L.}, year={2018}, pages={154–155} }
 @article{adkins_franks_murray_2017, title={Demonstration of extended field-of-view ultrasound’s potential to increase the pool of muscles for which in vivo fascicle length is measurable}, volume={63}, DOI={10.1016/j.jbiomech.2017.08.012}, abstractNote={Static, B-mode ultrasound is the most common method of measuring fascicle length in vivo. However, most forearm muscles have fascicles that are longer than the field-of-view of traditional ultrasound (T-US). As such, little work has been done to quantify in vivo forearm muscle architecture. The extended field-of-view ultrasound (EFOV-US) method, which fits together a sequence of B-mode images taken from a continuous ultrasound scan, facilitates direct measurements of longer, curved fascicles. Here, we test the validity and reliability of the EFOV-US method for obtaining fascicle lengths in the extensor carpi ulnaris (ECU). Fascicle lengths from images of the ECU captured in vivo with EFOV-US were compared to lengths from a well-established method, T-US. Images were collected in a joint posture that shortens the ECU such that entire fascicle lengths were captured within a single T-US image. Resulting measurements were not significantly different (p = 0.18); a Bland-Altman test demonstrated their agreement. A novice sonographer implemented EFOV-US in a phantom and in vivo on the ECU. The novice sonographer's measurements from the ultrasound phantom indicate that the combined imaging and analysis method is valid (average error = 2.2 ± 1.3 mm) and the in vivo fascicle length measurements demonstrate excellent reliability (ICC = 0.97). To our knowledge, this is the first study to quantify in vivo fascicle lengths of the ECU using any method. The ability to define a muscle's architecture in vivo using EFOV-US could lead to improvements in diagnosis, model development, surgery guidance, and rehabilitation techniques.}, journal={Journal of Biomechanics}, author={Adkins, A.N. and Franks, P.W. and Murray, W.M.}, year={2017}, month={Oct}, pages={179–185} }
 @article{aleman_adkins_boies_al-quiati_sako_bhattacharya_2017, title={Effects of Cinching Force on the Tricuspid Annulus: a Species Comparison}, volume={5}, DOI={10.4172/2329-9517.1000283}, abstractNote={Purpose Tricuspid annuloplasty rings are commonly used to cinch an enlarged tricuspid annulus back to its original shape and size in patients with severe functional tricuspid regurgitation. However, the invasive operation is contraindicated for patients at risk for reoperation. Fortunately, transcatheter repair procedures, currently in the development process, are minimally invasive alternatives to current repair techniques. This study aims to determine the species-dependence of cinching force with the potential of informing transcatheter repair design by quantifying the minimum required cinching force necessary to reduce tricuspid regurgitation. Methods The cinching force necessary to reduce the septal-lateral diameter of a dilated annuls was quantified and compared in ten ovine hearts and nine porcine hearts. Additionally, a deparaffinization protocol and Verhoeff-Van Gieson stain were used to compare the microscopic structure of tissue samples at different stages of the experimental procedure in the two species. Results The maximum annulus dilation observed for the porcine was 11.2%, and the maximum cinching force was 0.40 ± 0.12 N. As previously demonstrated, ovine hearts yielded a maximum annulus dilation and cinching force of 8.82% and 0.38 ± 0.09 N respectively. Histological stains revealed no gross tissue differences between ovine and porcine septal or free wall tissues. Conclusion The cinching force was not species dependent between ovine and porcine models. This study is an essential first step for determining which animal model should be utilized for the development of transcatheter devices.}, number={283}, journal={Journal of Cardiovascular Disease and Diagnosis}, author={Aleman, J. and Adkins, A.N. and Boies, L. and Al-Quiati, F. and Sako, E. and Bhattacharya, S.}, year={2017} }
 @inproceedings{adkins_murray_2017, title={Extended Field-of-View Ultrasound Does Not Yield Greater Error than Traditional Ultrasound}, author={Adkins, A.N. and Murray, W.M.}, year={2017}, month={Oct} }
 @inproceedings{adkins_franks_murray_2017, title={Extended Field-of-View Ultrasound in the Extensor Carpi Ulnaris}, author={Adkins, A.N. and Franks, P. and Murray, W.M.}, year={2017}, month={Aug} }
 @inproceedings{adkins_jesus_boies_sako_bhattacharya_2015, title={Force Required to Cinch the Tricuspid Annulus: an ex vivo study}, author={Adkins, A.N. and Jesus, A. and Boies, L. and Sako, E. and Bhattacharya, S.}, year={2015}, month={Jun} }
 @article{adkins_aleman_boies_sako_bhattacharya_2015, title={Force Required to Cinch the Tricuspid Annulus: an ex-vivo study}, volume={24}, number={5}, journal={Journal of Heart Valve Disease}, author={Adkins, A.N. and Aleman, J and Boies, L and Sako, E and Bhattacharya, S}, year={2015} }
 @inproceedings{adkins_brown_hord_bolch_criscione_2014, title={Durability of a Device Designed for Cardiac Assist and Support in a Failing Heart}, author={Adkins, A.N. and Brown, K. and Hord, E. and Bolch, C. and Criscione, J.C}, year={2014}, month={Oct} }