@article{enomoto_castro_hash_thomson_nakanishi-hester_perry_aker_haupt_opperman_roe_et al._2024, title={Prevalence of radiographic appendicular osteoarthritis and associated clinical signs in young dogs}, volume={14}, ISSN={["2045-2322"]}, DOI={10.1038/s41598-024-52324-9}, abstractNote={Abstract}, number={1}, journal={SCIENTIFIC REPORTS}, author={Enomoto, Masataka and Castro, Nicholas and Hash, Jonathan and Thomson, Andrea and Nakanishi-Hester, Aoi and Perry, Erin and Aker, Savannah and Haupt, Emily and Opperman, Logan and Roe, Simon and et al.}, year={2024}, month={Feb} }
 @article{sai_nakanishi_scofield_tokarz_linder_cohen_ninomiya-tsuji_2023, title={Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer?s disease mouse models}, volume={136}, ISSN={["1477-9137"]}, url={http://dx.doi.org/10.1242/jcs.260102}, DOI={10.1242/jcs.260102}, abstractNote={ABSTRACT}, number={6}, journal={JOURNAL OF CELL SCIENCE}, publisher={The Company of Biologists}, author={Sai, Kazuhito and Nakanishi, Aoi and Scofield, Kimberly M. and Tokarz, Debra A. and Linder, Keith E. and Cohen, Todd J. and Ninomiya-Tsuji, Jun}, year={2023}, month={Mar} }
 @article{nakanishi_lascelles_allen_case_gearing_enomoto_2022, title={A Pilot, Open-Label Study to Evaluate the Efficacy of Intra-Articular Administration of a Caninized TNF Receptor Fc Fusion Protein as a Treatment for Osteoarthritis-Associated Joint Pain}, volume={9}, ISSN={["2297-1769"]}, DOI={10.3389/fvets.2022.836709}, abstractNote={Tumor necrosis factor-α (TNF-α) is a potential target for osteoarthritis (OA) treatment. In several recent clinical studies in human OA, anti-TNF-α therapy showed promising results; however, these were open-label and based on patient-reported outcome measures. In this study, we developed a caninized TNF-α receptor-Fc (caTNFR-Fc) fusion protein and conducted a non-randomized, open-label, pilot study in dogs with OA using objectively measured ground reaction forces and activity. The aims of the study were to assess the efficacy of the intra-articular (IA) injection of the caTNFR-Fc fusion protein as a treatment for OA pain, and additionally to evaluate TNF concentrations in synovial fluid (SF) between joints with/without OA in dogs. Dogs (n = 12) with single-limb lameness due to single joint appendicular OA were recruited. All dogs received caTNFR-Fc fusion protein injection into the affected joint under sedation. Objective kinetic gait analysis using force plate was performed prior to (baseline), and at 14- and 28-days following treatment. Additionally, SF samples were collected from OA joints (n = 69) and non-OA joints (n = 79) in a different cohort of dogs and TNF-α were measured using enzyme-linked immunosorbent assay. No significant treatment effects on the limb use, activity, and the questionnaire were found. The concentration of TNF-α was significantly higher in OA joints than in healthy joints (p = 0.0019), but TNF-α was detected in only 10/69 OA samples. The IA injection of caTNFR-Fc fusion protein provided no benefit in terms of objective limb use and activity data in dogs with OA in this pilot study. Although the SF concentration of TNF-α was significantly higher in OA joints, few OA joints had measurable TNF-α. Collectively, the data indicate TNF-α may not be a good therapeutic target in canine OA.}, journal={FRONTIERS IN VETERINARY SCIENCE}, author={Nakanishi, Aoi and Lascelles, B. Duncan X. and Allen, Julie and Case, Beth and Gearing, David and Enomoto, Masataka}, year={2022}, month={Jun} }
 @article{prefarrow fat supplementation impact on piglet survival, reproduction_2022, url={https://www.nationalhogfarmer.com/nutrition/prefarrow-fat-supplementation-impact-piglet-survival-reproduction}, journal={National Hog Farmer}, year={2022}, month={May} }
 @article{summer body condition at farrowing influences litter size_2022, url={https://www.nationalhogfarmer.com/livestock/summer-body-condition-farrowing-influences-litter-size}, journal={National Hog Farmer}, year={2022}, month={Sep} }
 @article{2021 adsa undergraduate scholarship recognition awards _2021, url={https://www.sciencedirect.com/science/article/pii/S0022030221010067}, journal={Journal of Dairy Science}, year={2021}, month={Nov} }
 @article{abstracts‐posters_2021, volume={19}, url={http://dx.doi.org/10.1111/vco.12764}, DOI={10.1111/vco.12764}, number={S1}, journal={Veterinary and Comparative Oncology}, publisher={Wiley}, year={2021}, month={Sep}, pages={4–24} }