Andrew Neilson

Krueger, E. S. S., Griffin, L. E. E., Beales, J. L. L., Lloyd, T. S. S., Brown, N. J. J., Elison, W. S. S., … Tessem, J. S. S. (2023). Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health. METABOLITES, 13(7). https://doi.org/10.3390/metabo13070801

Satheesh Babu, A. K., Petersen, C., Iglesias-Carres, L., Paz, H. A., Wankhade, U. D., Neilson, A. P., & Anandh Babu, P. V. (2023, November 3). Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N-oxide by modulating gut microbes. BIOFACTORS. https://doi.org/10.1002/biof.2014

Iglesias-Carres, L., Chadwick-Corbin, S. A., Sweet, M. G., & Neilson, A. P. (2023). Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 120. https://doi.org/10.1016/j.jnutbio.2023.109428

Babu, A. K. S., Petersen, C., Paz, H. A., Iglesias-Carres, L., Li, Y., Zhong, Y., … Babu, P. V. A. (2023, December 6). Gut Microbiota Depletion Using Antibiotics to Investigate Diet-Derived Microbial Metabolites: An Efficient Strategy. MOLECULAR NUTRITION & FOOD RESEARCH. https://doi.org/10.1002/mnfr.202300386

Iglesias-Carres, L., Bruno, A., 'Antuono, I., Linsalata, V., Cardinali, A., & Neilson, A. P. (2023). In vitro evidences of the globe artichoke antioxidant, cardioprotective and neuroprotective effects. JOURNAL OF FUNCTIONAL FOODS, 107. https://doi.org/10.1016/j.jff.2023.105674

Iglesias-Carres, L., Racine, K. C., Chadwick, S., Nunn, C., Kalambur, S. B., Neilson, A. P., & Ferruzzi, M. G. (2023). Mechanism of off-color formation in potato chips fried in oil systems containing ascorbic acid as a stabilizer. LWT-FOOD SCIENCE AND TECHNOLOGY, 179. https://doi.org/10.1016/j.lwt.2023.114682

Hayes, M., Mohamedshah, Z., Chadwick-Corbin, S., Hoskin, R., Iorizzo, M., Lila, M. A., … Ferruzzi, M. G. (2022, March 8). Bioaccessibility and intestinal cell uptake of carotenoids and chlorophylls differ in powdered spinach by the ingredient form as measured using in vitro gastrointestinal digestion and anaerobic fecal fermentation models. FOOD & FUNCTION, Vol. 13. https://doi.org/10.1039/d2fo00051b

Mohamedshah, Z., Hayes, M., Chadwick-Corbin, S., Neilson, A. P., & Ferruzzi, M. G. (2022, March 9). Bioaccessibility, gut microbial metabolism and intestinal transport of phenolics from 100% Concord grape juice and whole grapes are similar in a simulated digestion and fecal fermentation model. FOOD & FUNCTION, Vol. 3. https://doi.org/10.1039/d1fo04226b

Racine, K. C., Iglesias-Carres, L., Herring, J. A., Ferruzzi, M. G., Kay, C. D., Tessem, J. S., & Neilson, A. P. (2022). Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 626, 205–210. https://doi.org/10.1016/j.bbrc.2022.08.018

Weikart, D. K., Indukuri, V. V., Racine, K. C., Coleman, K. M., Kovac, J., Cockburn, D. W., … Lambert, J. D. (2022). Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 109. https://doi.org/10.1016/j.jnutbio.2022.109117

Cheatham, C. L., Nieman, D. C., Neilson, A. P., & Lila, M. A. (2022). [Review of Enhancing the Cognitive Effects of Flavonoids With Physical Activity: Is There a Case for the Gut Microbiome?]. FRONTIERS IN NEUROSCIENCE, 16. https://doi.org/10.3389/fnins.2022.833202

Griffin, L. E., Kohrt, S. E., Rathore, A., Kay, C. D., Grabowska, M. M., & Neilson, A. P. (2022). Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 74(1), 194–210. https://doi.org/10.1080/01635581.2020.1869277

Iglesias-Carres, L., Racine, K. C., & Neilson, A. P. (2022, July 11). Phenolic-rich beverages reduce bacterial TMA formation in an ex vivo-in vitro colonic fermentation model. FOOD & FUNCTION. https://doi.org/10.1039/d2fo01159j

Iglesias-Carres, L., Krueger, E. S., Herring, J. A., Tessem, J. S., & Neilson, A. P. (2022). Potential of Phenolic Compounds and Their Gut Microbiota-Derived Metabolites to Reduce TMA Formation: Application of an In Vitro Fermentation High-Throughput Screening Model. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70(10), 3207–3218. https://doi.org/10.1021/acs.jafc.2c00247

Virdee, M. S., Saini, N., Kay, C. D., Neilson, A. P., Kwan, S. T. C., Helfrich, K. K., … Smith, S. M. (2021). An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder. SCIENTIFIC REPORTS, 11(1). https://doi.org/10.1038/s41598-020-80093-8

Griffin, L. E., Essenmacher, L., Racine, K. C., Iglesias-Carres, L., Tessem, J. S., Smith, S. M., & Neilson, A. P. (2021). Diet-induced obesity in genetically diverse collaborative cross mouse founder strains reveals diverse phenotype response and amelioration by quercetin treatment in 129S1/SvImJ, PWK/EiJ, CAST/PhJ, and WSB/EiJ mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 87. https://doi.org/10.1016/j.jnutbio.2020.108521

Steele, C. N., Baugh, M. E., Griffin, L. E., Neilson, A. P., Davy, B. M., Hulver, M. W., & Davy, K. P. (2021). Fasting and postprandial trimethylamine N-oxide in sedentary and endurance-trained males following a short-term high-fat diet. PHYSIOLOGICAL REPORTS, 9(16). https://doi.org/10.14814/phy2.14970

Krueger, E. S., Beales, J. L., Russon, K. B., Elison, W. S., Davis, J. R., Hansen, J. M., … Tessem, J. S. (2021). Gut Metabolite Trimethylamine N-Oxide Protects INS-1 beta-Cell and Rat Islet Function under Diabetic Glucolipotoxic Conditions. BIOMOLECULES, 11(12). https://doi.org/10.3390/biom11121892

Brunt, V. E., Casso, A. G., Gioscia-Ryan, R. A., Sapinsley, Z. J., Ziemba, B. P., Clayton, Z. S., … Seals, D. R. (2021). Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans. HYPERTENSION, 78(2), 499–511. https://doi.org/10.1161/HYPERTENSIONAHA.120.16895

Bruno, R. S., Neilson, A. P., Lambert, J. D., & Moustaid-Moussa, N. (2021, March). Journal of Nutritional Biochemistry Special Issue: Polyphenols, obesity, and cardiometabolic health. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, Vol. 89. https://doi.org/10.1016/j.jnutbio.2020.108565

Mitchell, C. M., Davy, B. M., Ponder, M. A., McMillan, R. P., Hughes, M. D., Hulver, M. W., … Davy, K. P. (2021). Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. NUTRIENTS, 13(9). https://doi.org/10.3390/nu13093235

Jin, Q., Sean F. O'Keefe, Stewart, A. C., Neilson, A. P., Kim, Y.-T., & Huang, H. (2021). Techno-economic analysis of a grape pomace biorefinery: Production of seed oil, polyphenols, and biochar. FOOD AND BIOPRODUCTS PROCESSING, 127, 139–151. https://doi.org/10.1016/j.fbp.2021.02.002

Brunt, V. E., LaRocca, T. J., Bazzoni, A. E., Sapinsley, Z. J., Miyamoto-Ditmon, J., Gioscia-Ryan, R. A., … Seals, D. R. (2021). The gut microbiome-derived metabolite trimethylamineN-oxide modulates neuroinflammation and cognitive function with aging. GEROSCIENCE, 43(1), 377–394. https://doi.org/10.1007/s11357-020-00257-2

Iglesias-Carres, L., Hughes, M. D., Steele, C. N., Ponder, M. A., Davy, K. P., & Neilson, A. P. (2021). Use of dietary phytochemicals for inhibition of trimethylamine N-oxide formation. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 91. https://doi.org/10.1016/j.jnutbio.2021.108600

Iglesias-Carres, L., & Neilson, A. P. (2021, October 14). Utilizing preclinical models of genetic diversity to improve translation of phytochemical activities from rodents to humans and inform personalized nutrition. FOOD & FUNCTION. https://doi.org/10.1039/d1fo02782d

Wang, Y., Wang, A., Alkhalidy, H., Luo, J., Moomaw, E., Neilson, A. P., & Liu, D. (2020). Flavone Hispidulin Stimulates Glucagon-Like Peptide-1 Secretion and Ameliorates Hyperglycemia in Streptozotocin-Induced Diabetic Mice. MOLECULAR NUTRITION & FOOD RESEARCH, 64(6). https://doi.org/10.1002/mnfr.201900978

Jin, Q., Wang, Z., Feng, Y., Kim, Y.-T., Stewart, A. C., Sean F. O'Keefe, … Huang, H. (2020). Grape pomace and its secondary waste management: Biochar production for a broad range of lead (Pb) removal from water. ENVIRONMENTAL RESEARCH, 186. https://doi.org/10.1016/j.envres.2020.109442

Li, M., Griffin, L. E., Corbin, S., Neilson, A. P., & Ferruzzi, M. G. (2020). Modulating Phenolic Bioaccessibility and Glycemic Response of Starch-Based Foods in Wistar Rats by Physical Complexation between Starch and Phenolic Acid. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(46), 13257–13266. https://doi.org/10.1021/acs.jafc.0c01387

Baugh, M. E., Bowser, S. M., McMillan, R. P., Davy, B. M., Essenmacher, L. A., Neilson, A. P., … Davy, K. P. (2020). Postprandial skeletal muscle metabolism following a high-fat diet in sedentary and endurance-trained males. JOURNAL OF APPLIED PHYSIOLOGY, 128(4), 872–883. https://doi.org/10.1152/japplphysiol.00576.2019

Griffin, L. E., Diako, C., Miller, L. E., Neilson, A. P., Ross, C. F., & Stewart, A. C. (2020). Preference for and sensitivity to flavanol mean degree of polymerization in model wines is correlated with body composition. APPETITE, 144. https://doi.org/10.1016/j.appet.2019.104442

Bowser, S. M., McMillan, R. P., Boutagy, N. E., Tarpey, M. D., Smithson, A. T., Osterberg, K. L., … Hulver, M. W. (2020). Serum endotoxin, gut permeability and skeletal muscle metabolic adaptations following a short term high fat diet in humans. METABOLISM-CLINICAL AND EXPERIMENTAL, 103. https://doi.org/10.1016/j.metabol.2019.154041

Lloyd, T., Griffin, L., Krueger, E., Beales, J., Barlow, A., Sheets, J., … Tessem, J. (2020, April). Supplemental treatment options for diabetes: how flavanol metabolites improve beta-cell function. FASEB JOURNAL, Vol. 34. https://doi.org/10.1096/fasebj.2020.34.s1.05762

Brunt, V. E., Gioscia-Ryan, R. A., Casso, A. G., VanDongen, N. S., Ziemba, B. P., Sapinsley, Z. J., … Seals, D. R. (2020). Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans. HYPERTENSION, 76(1), 101–112. https://doi.org/10.1161/HYPERTENSIONAHA.120.14759

Griffin, L. E., Djuric, Z., Angiletta, C. J., Mitchell, C. M., Baugh, M. E., Davy, K. P., & Neilson, A. P. (2019). A Mediterranean diet does not alter plasma trimethylamine N-oxide concentrations in healthy adults at risk for colon cancer. FOOD & FUNCTION, 10(4), 2138–2147. https://doi.org/10.1039/c9fo00333a

Ma, S., Kim, C., Neilson, A. P., Griffin, L. E., Peck, G. M., Sean F. O'Keefe, & Stewart, A. C. (2019). Comparison of Common Analytical Methods for the Quantification of Total Polyphenols and Flavanols in Fruit Juices and Ciders. JOURNAL OF FOOD SCIENCE, 84(8), 2147–2158. https://doi.org/10.1111/1750-3841.14713

Jin, Q., O'Hair, J., Stewart, A. C., Sean F. O'Keefe, Neilson, A. P., Kim, Y.-T., … Huang, H. (2019). Compositional Characterization of Different Industrial White and Red Grape Pomaces in Virginia and the Potential Valorization of the Major Components. FOODS, 8(12). https://doi.org/10.3390/foods8120667

Racine, K. C., Lee, A. H., Stewart, A. C., Blakeslee, K. W., & Neilson, A. P. (2019). Development of a rapid ultra performance hydrophilic interaction liquid chromatography tandem mass spectrometry method for procyanidins with enhanced ionization efficiency. JOURNAL OF CHROMATOGRAPHY A, 1594, 54–64. https://doi.org/10.1016/j.chroma.2019.02.007

Racine, K. C., Wiersema, B. D., Griffin, L. E., Essenmacher, L. A., Lee, A. H., Hopfer, H., … Neilson, A. P. (2019). Flavanol Polymerization Is a Superior Predictor of alpha-Glucosidase Inhibitory Activity Compared to Flavanol or Total Polyphenol Concentrations in Cocoas Prepared by Variations in Controlled Fermentation and Roasting of the Same Raw Cocoa Beans. ANTIOXIDANTS, 8(12). https://doi.org/10.3390/antiox8120635

Griffin, L. E., Fausnacht, D. W., Tuzo, J. L., Addington, A. K., Racine, K. C., Zhang, H., … Stewart, A. C. (2019). Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet. NUTRITION RESEARCH, 66, 32–47. https://doi.org/10.1016/j.nutres.2019.03.011