Anka Nikolova Veleva

Works (10)

Updated: April 5th, 2024 03:59

2020 journal article

Scalable Formation of Concentrated Monodisperse Lignin Nanoparticles by Recirculation-Enhanced Flash Nanoprecipitation

PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 37(7).

By: C. Conner n, A. Veleva n, V. Paunov *, S. Stoyanov* & O. Velev n 

author keywords: benign nanomaterials; flash nanoprecipitation; monodisperse lignin nanoparticles; scale-up
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 22, 2020

2016 journal article

Data on biodistribution and radiation absorbed dose profile of a novel 64Cu-labeled high affinity cell-specific peptide for positron emission tomography imaging of tumor vasculature

Data in Brief, 7, 480–484.

By: J. Merrill *, K. Krajewski *, H. Yuan *, J. Frank*, D. Lalush n, C. Patterson*, A. Veleva n

author keywords: Molecular imaging; Tumor angiogenesis; Radiation absorbed dose; Diagnostic radiopharmaceuticals
TL;DR: Biodistribution measurements in mice are reported and the radiation absorbed doses to normal organs are calculated using a modified Medical Internal Radiation Dosimetry (MIRD) methodology that accounts for physical and geometric factors and cross-organ beta doses. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: November 21, 2020

2016 journal article

Synthesis and comparative evaluation of novel Cu-64-labeled high affinity cell-specific peptides for positron emission tomography imaging of tumor vasculature

BIOMATERIALS, 84, 241–249.

By: J. Merrill *, K. Krajewski *, H. Yuan *, J. Frank*, D. Lalush n, C. Patterson*, A. Veleva n

author keywords: Molecular imaging; Tumor angiogenesis; Cu-64-labeled cell-specific peptides; Diagnostic PET radiopharmaceuticals; Radiation absorbed dose
MeSH headings : Animals; Cell Line, Tumor; Copper Radioisotopes / chemistry; Dose-Response Relationship, Radiation; Female; Humans; Isotope Labeling; Mice, Inbred C57BL; Neoplasms / blood supply; Neoplasms / diagnostic imaging; Peptides / chemical synthesis; Peptides / chemistry; Positron-Emission Tomography / methods; Radiation Dosage; Tissue Distribution; Tomography, X-Ray Computed
TL;DR: The findings from this investigation warrant further development of (64)Cu-NOTA-FHT as a potential targeted diagnostic radiopharmaceutical for PET imaging of aggressive tumor vasculature. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Development of a New Positron Emission Tomography Tracer for Targeting Tumor Angiogenesis: Synthesis, Small Animal Imaging, and Radiation Dosimetry

MOLECULES, 18(5), 5594–5610.

By: C. Patterson*, C. Frederick n, H. Yuan *, L. Dyer *, P. Lockyer *, D. Lalush n, A. Veleva n

author keywords: development of new 64Cu radiolabeled peptide; radiopharmaceuticals; targeted radioconjugates; positron emission tomography (PET) imaging; tumor angiogenesis; tumor aggressiveness; responses to therapy
MeSH headings : Animals; Carcinoma, Lewis Lung / diagnostic imaging; Carcinoma, Lewis Lung / metabolism; Copper / chemistry; Female; Isotopes / chemistry; Mice; Neovascularization, Pathologic / diagnostic imaging; Neovascularization, Pathologic / metabolism; Peptides / chemical synthesis; Peptides / chemistry; Peptides / pharmacology; Positron-Emission Tomography; Radiography; Radiopharmaceuticals / chemical synthesis; Radiopharmaceuticals / chemistry; Radiopharmaceuticals / pharmacology
TL;DR: The results from this study show that, in the context of the s.c. LLC immunocompetent mouse model, the QFP-tracer can target tumor blood vessels selectively, however, further optimization of the biodistribution and dosimetry profile of the tracer is necessary to ensure efficient radiopharmaceutical applications enabled by the biological specificity of the Q FP-peptide. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Efficient In Vivo Selection of a Novel Tumor-Associated Peptide from a Phage Display Library

MOLECULES, 16(1), 900–914.

By: A. Veleva n, D. Nepal*, C. Frederick n, J. Schwab*, P. Lockyer *, H. Yuan *, D. Lalush n, C. Patterson*

author keywords: in vivo phage display; circulating bone marrow derived tumor homing cells; tumor-associated peptides; targeting neovascular growth; positron emission tomography (PET) imaging
MeSH headings : Amino Acid Sequence; Animals; Bacteriophages / genetics; Mice; Neoplasms, Experimental / genetics; Peptides / chemistry; Peptides / genetics; Peptides / isolation & purification
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Recombinant Human Interleukin-11 Treatment Enhances Collateral Vessel Growth After Femoral Artery Ligation

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 31(2), 306–312.

By: J. Aitsebaomo n, S. Srivastava  n, H. Zhang  n, S. Jha  n, Z. Wang  n, S. Winnik  n, A. Veleva n, X. Pi  n ...

author keywords: blood flow; ischemia; peripheral arterial disease; peripheral vasculature; reperfusion
MeSH headings : Animals; Antigens, CD34 / metabolism; Cell Movement / drug effects; Cell Movement / physiology; Cells, Cultured; Disease Models, Animal; Femoral Artery / cytology; Femoral Artery / drug effects; Femoral Artery / growth & development; Hindlimb / blood supply; Humans; Interleukin-11 / pharmacology; Ischemia / metabolism; Ischemia / pathology; Leukocytes, Mononuclear / cytology; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / metabolism; Ligation; Mice; Neovascularization, Physiologic / physiology; Recombinant Proteins / pharmacology; STAT3 Transcription Factor / metabolism; Vascular Endothelial Growth Factor Receptor-2 / metabolism
TL;DR: Findings show that rhIL-11 promotes in vivo mobilization of CD34+/VEGFR2+ mononuclear cells, enhances collateral vessel growth, and increases recovery of perfusion after femoral artery ligation, and has a promising role for development as an adjunctive treatment of patients with peripheral vascular disease. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Interactions between endothelial cells and electrospun methacrylic terpolymer fibers for engineered vascular replacements

Journal of Biomedical Materials Research Part A, 91A(4), 1131–1139.

By: A. Veleva n, D. Heath *, J. Johnson *, J. Nam *, C. Patterson*, J. Lannutti *, S. Cooper *

author keywords: methacrylic terpolymers; biocompatibility; electrospinning; endothelial cells; engineered vascular grafts
MeSH headings : Blood Vessel Prosthesis; Cell Adhesion / drug effects; Cell Communication / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Endothelial Cells / cytology; Endothelial Cells / drug effects; Endothelial Cells / metabolism; Humans; Methacrylates / pharmacology; Microscopy, Electron, Scanning; Polymers / pharmacology; Porosity / drug effects; Tissue Engineering / methods; von Willebrand Factor / metabolism
TL;DR: It was found that the terpolymer is cytocompatible allowing endothelial cell growth, with random fibers being more effective in promoting enhanced cellular activities than oriented fibers. (via Semantic Scholar)
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Source: Crossref
Added: February 24, 2020

2008 journal article

Selective endothelial cell attachment to peptide-modified terpolymers

BIOMATERIALS, 29(27), 3656–3661.

By: A. Veleva n, D. Heath *, S. Cooper* & C. Patterson*

author keywords: phage display-selected-peptide ligands; cell-specific adhesion; HBOEC; bioactive terpolymers; autologous cell therapies
MeSH headings : Amino Acid Sequence; Cell Adhesion; Cells, Cultured; Endothelium, Vascular / cytology; Humans; Ligands; Polymers
TL;DR: This is the first report demonstrating specificity in binding to peptide-modified biomaterials of mature EC, i.e., HUVEC, and EC of progenitor origin such as HBOEC. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 journal article

Selection and initial characterization of novel peptide ligands that bind specifically to human blood outgrowth endothelial cells

BIOTECHNOLOGY AND BIOENGINEERING, 98(1), 306–312.

By: A. Veleva n, S. Cooper* & C. Patterson*

author keywords: human blood outgrowth endothelial cells (HBOEC); phage displayed peptide library screening; cell-specific; peptides; progenitor cell-based therapies
MeSH headings : Endothelial Cells / metabolism; Humans; Ligands; Peptide Library; Peptides / metabolism; Protein Binding; Protein Interaction Mapping / methods
TL;DR: The isolated 12-mer peptide ligands that bind to human blood outgrowth endothelial cells (HBOEC) display outstanding cell specificity and are expected to be exploited in the development of future cell-based therapeutic revascularization approaches to ischemic disease and endothelial injury. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Oxidative and hydrolytic stability of a novel acrylic terpolymer for biomedical applications

Journal of Biomedical Materials Research Part A, 74A(1), 117–123.

By: A. Veleva n, S. Khan n  & S. Cooper*

author keywords: acrylic terpolymers; in vitro biostability; oxidative stress; hydrolytic stress; small-diameter vascular grafts
MeSH headings : Acrylic Resins / chemical synthesis; Acrylic Resins / chemistry; Biocompatible Materials / chemistry; Buffers; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Cobalt / chemistry; Elastomers; Hydrogen Peroxide / chemistry; Hydrolysis; Lysosomes / enzymology; Magnetic Resonance Spectroscopy; Materials Testing; Methacrylates / chemistry; Methylmethacrylate / chemistry; Oxidation-Reduction; Phospholipases A / chemistry; Phospholipases A2; Polymethyl Methacrylate / chemical synthesis; Polymethyl Methacrylate / chemistry; Sterol Esterase / chemistry; Tensile Strength
TL;DR: The results from this study indicate excellent biostability of HMA-MMA- MAA terpolymers and thus their potential for use in biomedical devices for long-term implantation. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

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