Works (12)

Updated: June 15th, 2024 05:02

2024 journal article

Assessment of Early Glaucomatous Optic Neuropathy in the Dog by Spectral Domain Optical Coherence Tomography (SD-OCT)

Micromachines.

By: A. Oh, C. Harman, K. Koehl, J. Huang, L. Teixeira, L. Occelli, E. Storey, G. Ying, A. Komáromy

Source: ORCID
Added: June 15, 2024

2023 journal article

Effect of gentamicin on <scp>CD3</scp>+ T‐lymphocyte proliferation for treatment of equine recurrent uveitis: An in vitro study

Veterinary Ophthalmology, 26(4), 347–354.

author keywords: autoimmune disease; equine recurrent uveitis; gentamicin; horse; immunology; intravitreal injection
TL;DR: Gentamicin had no effect on equine peripheral blood CD3+ T-lymphocyte cell viability and proliferation in concentrations ranging from "safe" to "retinotoxic" in relation to intravitreal injection volumes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: April 29, 2023

2023 journal article

Ex vivo analysis of ultraviolet radiation transmission through ocular media and retina in select species

Experimental Eye Research, 233, 109550.

By: N. Himebaugh n, J. Robertson n, K. Weninger n, B. Gilger n, B. Ekesten* & A. Oh n

author keywords: Ultraviolet radiation; Ocular media; Canine; Feline; Human; Vision
TL;DR: The globes of cats and dogs allowed the most amount of UV radiation transmission, while those of pigs and humans allowed the least amount ofUV radiation transmission. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: June 25, 2023

2023 article

Primary ocular hemangiosarcoma in a dog

Murillo, D. F. B., Souza Teixeira Campos, M. E., Oh, A., Smith, H., & Watanabe, T. T. N. (2023, October 12). VETERINARY RECORD CASE REPORTS, Vol. 10.

By: D. Murillo*, M. Souza Teixeira Campos*, A. Oh n, H. Smith n & T. Watanabe n

author keywords: dogs; eyes; histopathology; neoplasia; ophthalmology; ocular hemangiosarcoma
TL;DR: A 10‐year‐old, male, neutered Boxer dog had an ulcerated mass covering nearly 90% of the left cornea and histological findings confirmed corneal hemangiosarcoma with neoplastic extension to the limbus/conjunctiva. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 30, 2023

2022 journal article

Polidocanol monotherapy for a superficial orbital venous malformation in a horse

Veterinary Ophthalmology, 25(5), 412–418.

By: T. Stonex n, A. Zibura n, M. Andres n, B. Gilger n & A. Oh n

author keywords: horse; monotherapy; orbit; polidocanol; sclerotherapy; venous malformation
MeSH headings : Animals; Horse Diseases / chemically induced; Horse Diseases / diagnostic imaging; Horse Diseases / drug therapy; Horses; Male; Orbital Diseases / veterinary; Polidocanol / therapeutic use; Polyethylene Glycols; Sclerosing Solutions / adverse effects; Sclerosing Solutions / therapeutic use; Sclerotherapy / veterinary; Treatment Outcome; Veins / abnormalities
TL;DR: Polidocanol as the sole treatment for a superficial orbital venous malformation in a horse was well tolerated and led to clinical resolution, and sclerosant monotherapy may be a safe treatment option for superficial orbital Venous malformations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: June 2, 2022

2021 journal article

Whole-genome sequencing identifies missense mutation inGRM6as the likely cause of congenital stationary night blindness in a Tennessee Walking Horse

EQUINE VETERINARY JOURNAL, 53(2), 316–323.

By: Y. Hack*, E. Crabtree n, F. Avila*, R. Sutton*, R. Grahn*, A. Oh n, B. Gilger n, R. Bellone*

author keywords: horse; congenital stationary night blindness (CSNB); genetics; genomics; Tennessee Walking Horse; GRM6
MeSH headings : Animals; Eye Diseases, Hereditary / genetics; Eye Diseases, Hereditary / veterinary; Genetic Diseases, X-Linked; Horse Diseases / genetics; Horses; Mutation, Missense; Myopia; Night Blindness / genetics; Night Blindness / veterinary; Receptors, Glutamate / genetics; Tennessee
TL;DR: A likely causal recessive missense variant in metabotropic glutamate receptor 6 (GRM6) is identified, which alters GRM6 binding, and thus signaling from the retinal rod cell to the ON-bipolar cell, impairing vision in low light conditions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 17, 2020

2019 journal article

Circulating neurohormone imbalances in canine sudden acquired retinal degeneration syndrome and canine pituitary-dependent hypercortisolism

JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(6), 2587–2594.

By: A. Oh n, M. Foster n, K. Lunn n & F. Mowat n

author keywords: dog; dopamine; melatonin; PDH; retina; SARDS; serotonin
MeSH headings : Animals; Case-Control Studies; Dog Diseases / blood; Dog Diseases / metabolism; Dogs; Dopamine / blood; Melatonin / analogs & derivatives; Melatonin / blood; Melatonin / urine; Pituitary ACTH Hypersecretion / blood; Pituitary ACTH Hypersecretion / metabolism; Pituitary ACTH Hypersecretion / veterinary; Prospective Studies; Retinal Degeneration / blood; Retinal Degeneration / metabolism; Retinal Degeneration / veterinary; Serotonin / blood
TL;DR: This study has identified neurohormone differences between dogs with SARDS and PDH, although the study was underpowered for detection of significant differences in serum serotonin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 11, 2019

2019 journal article

Diagnostic utility of clinical and laboratory test parameters for differentiating between sudden acquired retinal degeneration syndrome and pituitary‐dependent hyperadrenocorticism in dogs

Veterinary Ophthalmology, 22(6), 842–858.

By: A. Oh n, M. Foster n, J. Williams n, C. Zheng n, H. Ru n, K. Lunn n, F. Mowat n

author keywords: biomarker; dog; hyperadrenocorticism; retina; sudden acquired retinal degeneration syndrome
MeSH headings : Animals; Case-Control Studies; Dog Diseases / diagnosis; Dogs; Electroretinography / veterinary; Female; Male; Pituitary ACTH Hypersecretion / diagnosis; Pituitary ACTH Hypersecretion / veterinary; Retina / pathology; Retinal Degeneration / diagnosis; Retinal Degeneration / veterinary; Tomography, Optical Coherence / veterinary
TL;DR: This work provides the basis for future studies that could identify and examine dogs with SARDS prior to vision loss, which may extend the potential therapeutic window for SARDS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: December 16, 2019

2019 journal article

In vivo electroretinographic differentiation of rod, short-wavelength and long/medium-wavelength cone responses in dogs using silent substitution stimuli

EXPERIMENTAL EYE RESEARCH, 185.

By: F. Mowat n, E. Wise n, A. Oh n, M. Foster n & J. Kremers*

author keywords: dog; Silent substitution; S-Cone; L/M-cone; Rod; Photoreceptor; Electroretinogram; Congenital stationary night blindness
MeSH headings : Animals; Cone Opsins / metabolism; Dark Adaptation; Disease Models, Animal; Dogs; Electroretinography / methods; Eye Diseases, Hereditary / metabolism; Eye Diseases, Hereditary / physiopathology; Female; Genetic Diseases, X-Linked / metabolism; Genetic Diseases, X-Linked / physiopathology; Male; Myopia / metabolism; Myopia / physiopathology; Night Blindness / metabolism; Night Blindness / physiopathology; Retina / metabolism; Retina / physiopathology; Retinal Cone Photoreceptor Cells / physiology; Retinal Rod Photoreceptor Cells / physiology
TL;DR: Methods to differentiate rod, S- and L/M-cone function in dogs using silent substitution methods have been developed and the influence of temporal frequency and mean luminance on the ERGs originating in each photoreceptor type can now be studied independently. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 16, 2019

2019 journal article

Safety and efficacy of topically applied 0.5% and 1% pirfenidone in a canine model of subconjunctival fibrosis

VETERINARY OPHTHALMOLOGY, 22(4), 502–509.

By: H. Westermeyer n, B. Salmon n, R. Baynes n, J. Yeatts n, A. Khattab n, A. Oh n, F. Mowat n

MeSH headings : Administration, Topical; Animals; Aqueous Humor / drug effects; Conjunctival Diseases / drug therapy; Conjunctival Diseases / pathology; Conjunctival Diseases / veterinary; Disease Models, Animal; Dogs; Drug Implants; Female; Fibrosis / drug therapy; Fibrosis / veterinary; Pyridones / administration & dosage; Pyridones / therapeutic use; Random Allocation
TL;DR: Pfenidone may decrease fibrosis following glaucoma shunt surgery and can potentially be used indefinitely due to minimal side effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 5, 2019

2018 journal article

Clinical therapeutic efficacy of mycophenolate mofetil in the treatment of SARDS in dogs-a prospective open-label pilot study

VETERINARY OPHTHALMOLOGY, 21(6), 565–576.

By: W. Young n, A. Oh n, J. Williams n, M. Foster n, W. Miller*, K. Lunn n, F. Mowat n

author keywords: dog; mycophenolate mofetil; retina; sudden acquired retinal degeneration syndrome; treatment; vision
MeSH headings : Animals; Dog Diseases / drug therapy; Dogs; Female; Immunosuppressive Agents / therapeutic use; Male; Mycophenolic Acid / therapeutic use; Pilot Projects; Prospective Studies; Retinal Degeneration / drug therapy; Retinal Degeneration / veterinary; Vision Tests / veterinary
TL;DR: The effect of sole-agent treatment with mycophenolate mofetil as a sole agent has no measureable positive effect on physical health, vision, or retinal structure following a 6-week trial period. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 3, 2018

2018 journal article

Phenotypic characterization of complete CSNB in the inbred research beagle: how common is CSNB in research and companion dogs?

DOCUMENTA OPHTHALMOLOGICA, 137(2), 87–101.

By: A. Oh n, E. Loew*, M. Foster n, M. Davidson n, R. English*, K. Gervais*, I. Herring*, F. Mowat n

author keywords: Congenital stationary night blindness; Dog; Electroretinography; Complete; Retina
MeSH headings : Adaptation, Ocular / physiology; Animals; Animals, Inbred Strains; Dark Adaptation / physiology; Dogs; Electroretinography; Eye Diseases, Hereditary / physiopathology; Genetic Diseases, X-Linked / physiopathology; Myopia / physiopathology; Night Blindness / physiopathology; Phenotype; Refraction, Ocular / physiology; Retina / physiopathology; Retinal Bipolar Cells / physiology; Retinal Rod Photoreceptor Cells / physiology; Retrospective Studies; Vision, Ocular / physiology
TL;DR: CSNB appears to be a rare disorder in the wider beagle population, although its detection could confound studies that use retinal function as an outcome measure in research dogs, necessitating careful baseline studies to be performed prior to experimentation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018

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