Abhijit Rangnekar

Works (3)

Updated: July 5th, 2023 15:44

2016 journal article

Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures

MOLECULES, 21(2).

By: A. Rangnekar n, J. Nash n, B. Goodfred  n, Y. Yingling n  & T. LaBean n

Contributors: A. Rangnekar n, J. Nash n, B. Goodfred  n, Y. Yingling n  & T. LaBean n

author keywords: thrombin; DNA aptamers; anticoagulation; DNA nanotechnology
MeSH headings : Anticoagulants / chemistry; Anticoagulants / pharmacology; Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / pharmacology; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Dynamics Simulation; Nanostructures / chemistry; Partial Thromboplastin Time
TL;DR: By using DNA strand displacement, this work was able to turn the coagulation cascade off and on as desired, thereby enabling significantly better control over blood coagulating. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 review

Building DNA DNA Nanostructures for Molecular Computation, Templated Assembly, and Biological Applications

[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 47(6), 1778–1788.

By: A. Rangnekar n & T. LaBean n

MeSH headings : Base Sequence; Biosensing Techniques; Computers, Molecular; DNA / chemistry; DNA, Single-Stranded / chemistry; Humans; Nanostructures / chemistry; Nanotechnology / methods; Nanowires
TL;DR: The tremendous progress in DNA nanotechnology over the past three decades will open even more research avenues in the near future for applications in a wide variety of disciplines including electronics, photonics, biomedical engineering, biosensing, therapeutics, and nucleic-acid-based drug delivery. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2012 journal article

An autonomously self-assembling dendritic DNA nanostructure for target DNA detection

BIOTECHNOLOGY JOURNAL, 8(2), 221–227.

By: H. Chandran*, A. Rangnekar n, G. Shetty*, E. Schultes *, J. Reif * & T. LaBean n

author keywords: DNA sequence detection; Hybridization cascade; Molecular self-assembly; Nanobiotechnology; Nucleic acids
MeSH headings : Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Chlamydia / isolation & purification; DNA / chemistry; DNA / isolation & purification; Electrophoresis, Polyacrylamide Gel; Gold / chemistry; HIV / isolation & purification; Metal Nanoparticles / chemistry; Nucleic Acid Conformation; Nucleic Acid Hybridization; Sequence Analysis, DNA / methods
TL;DR: A DNA detection system employing the triggered self-assembly of a novel DNA dendritic nanostructure that has minimal sequence constraints, allowing reconfiguration for the detection of arbitrary target sequences. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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