Works (3)
Updated: July 5th, 2023 15:44
2016 journal article
Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures
MOLECULES, 21(2).
Contributors: n, J. Nash n, B. Goodfred n, Y. Yingling n & T. LaBean n
author keywords: thrombin; DNA aptamers; anticoagulation; DNA nanotechnology
MeSH headings : Anticoagulants / chemistry; Anticoagulants / pharmacology; Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / pharmacology; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Dynamics Simulation; Nanostructures / chemistry; Partial Thromboplastin Time
TL;DR:
By using DNA strand displacement, this work was able to turn the coagulation cascade off and on as desired, thereby enabling significantly better control over blood coagulating.
(via Semantic Scholar)
open access via www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2014 review
Building DNA DNA Nanostructures for Molecular Computation, Templated Assembly, and Biological Applications
[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 47(6), 1778–1788.
MeSH headings : Base Sequence; Biosensing Techniques; Computers, Molecular; DNA / chemistry; DNA, Single-Stranded / chemistry; Humans; Nanostructures / chemistry; Nanotechnology / methods; Nanowires
TL;DR:
The tremendous progress in DNA nanotechnology over the past three decades will open even more research avenues in the near future for applications in a wide variety of disciplines including electronics, photonics, biomedical engineering, biosensing, therapeutics, and nucleic-acid-based drug delivery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
An autonomously self-assembling dendritic DNA nanostructure for target DNA detection
BIOTECHNOLOGY JOURNAL, 8(2), 221–227.
author keywords: DNA sequence detection; Hybridization cascade; Molecular self-assembly; Nanobiotechnology; Nucleic acids
MeSH headings : Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Chlamydia / isolation & purification; DNA / chemistry; DNA / isolation & purification; Electrophoresis, Polyacrylamide Gel; Gold / chemistry; HIV / isolation & purification; Metal Nanoparticles / chemistry; Nucleic Acid Conformation; Nucleic Acid Hybridization; Sequence Analysis, DNA / methods
TL;DR:
A DNA detection system employing the triggered self-assembly of a novel DNA dendritic nanostructure that has minimal sequence constraints, allowing reconfiguration for the detection of arbitrary target sequences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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