Allison R. Finger

Works (1)

Updated: July 5th, 2023 15:54

2007 article

Differential Effects on Messenger Ribonucleic Acid Expression by Bone Marrow–Derived Human Mesenchymal Stem Cells Seeded in Agarose Constructs Due to Ramped and Steady Applications of Cyclic Hydrostatic Pressure

Finger, A. R., Sargent, C. Y., Dulaney, K. O., Bernacki, S. H., & Loboa, E. G. (2007, April 18). Tissue Engineering.

By: A. Finger n, C. Sargent n, K. Dulaney n, S. Bernacki n & E. Loboa n

MeSH headings : Adolescent; Adult; Biocompatible Materials / chemistry; Bone Marrow Cells / cytology; Bone Marrow Cells / drug effects; Bone Marrow Cells / metabolism; Cell Culture Techniques / methods; Cells, Cultured; Chondrocytes / cytology; Chondrocytes / drug effects; Chondrocytes / metabolism; Chondrogenesis / drug effects; Chondrogenesis / physiology; Cytoskeletal Proteins / genetics; Cytoskeletal Proteins / metabolism; Gene Expression Regulation, Developmental / drug effects; Gene Expression Regulation, Developmental / physiology; Humans; Male; Mechanotransduction, Cellular / drug effects; Mechanotransduction, Cellular / physiology; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Pressure; RNA, Messenger / metabolism; Sepharose / chemistry; Tissue Engineering / methods; Transforming Growth Factor beta / administration & dosage
topics (OpenAlex): 3D Printing in Biomedical Research; Mesenchymal stem cell research; Proteoglycans and glycosaminoglycans research
TL;DR: Findings indicate that hydrostatic pressure may induce chondrogenesis in hMSC-seeded agarose constructs without TGF-beta, and that hMSCs are capable of withstanding high initial pressures that may initiate chondrogensesis faster than lower pressures. (via Semantic Scholar)
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Added: August 6, 2018

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