Adriana San Miguel
microfluidics, systems biology, quantitative image analysis, phenotyping, neurobiology, aging
Works (59)
2025 article
Amyloid β induces hormetic-like effects through major stress pathways in a C. elegans model of Alzheimer’s Disease
Lichty, J. D., Mane, H., Yarmey, V. R., & Miguel, A. S. (2025, April 24). (N. Tavernarakis, Ed.). PLoS ONE.
Ed(s): N. Tavernarakis
2025 article
Assessing PDMS Biocompatibility in Microfluidic Applications: Toxicity and Survival Outcomes in C. elegans
Gomez, K., Efimenko, K., Genzer, J., & San-Miguel, A. (2025, December 15).
2025 article
Data from: Assessing PDMS biocompatibility in microfluidic applications: Toxicity and survival outcomes in C. elegans.
San Miguel, A., & Gomez, K. (2025, December 15). DRYAD, Vol. 12.
Contributors: n & K. Gomez n
2025 article
Derivation of human trophoblast stem cells from placentas at birth
Karakis, V., Britt, J. W., Jabeen, M., Miguel, A. S., & Rao, B. M. (2025, April 10). Journal of Biological Chemistry, Vol. 301.
2025 article
Heat shock proteins function as signaling molecules to mediate neuron–glia communication in C. elegans during aging
Wu, J., Yarmey, V. R., Yang, O. J., Soderblom, E. J., San-Miguel, A., & Yan, D. (2025, June 18). Nature Neuroscience, Vol. 6.
2025 article
Microfluidic and Computational Tools for Neurodegeneration Studies
Gomez, K., Yarmey, V. R., Mane, H., & San-Miguel, A. (2025, January 15). Annual Review of Chemical and Biomolecular Engineering, Vol. 16, pp. 195–216.
2025 journal article
Pickering Emulsion for Enhanced Viability of Plant Growth Promoting Bacteria and Combined Delivery of Agrochemicals and Biologics
Advanced Functional Materials, 2.
2024 journal article
A primordial DNA store and compute engine
Nature Nanotechnology, 8.
2024 article
A quantitative image analysis platform for assessing trophoblast differentiation
Jabeen, M., Karakis, V., Britt, J., Miguel, A. S., & Rao, B. (2024, July 18). Placenta, Vol. 166, pp. 117–125.
Contributors: M. Jabeen n, V. Karakis n, J. Britt n, n & B. Rao n
2024 article
Amyloid β Induces Hormetic-Like Effects Through Major Stress Pathways in a C. elegans Model of Alzheimer’s Disease
Lichty, J. D., & Miguel, A. S. (2024, May 10).
2024 article
Biomarkers for aging in Caenorhabditis elegans high throughput screening
Yarmey, V. R., & San-Miguel, A. (2024, June 17). Biochemical Society Transactions, Vol. 6.
2024 article
Data from: Amyloid β induces hormetic-like effects through major stress pathways in a C. elegans model of Alzheimer’s disease
Lichty, J., Mane, H., Yarmey, V., & San Miguel, A. (2024, November 14). DRYAD.
2024 article
Derivation of human trophoblast stem cells from placentas at birth
Karakis, V., Britt, J. W., Jabeen, M., Miguel, A. S., & Rao, B. M. (2024, May 2). BioRxiv.
Contributors: V. Karakis n, J. Britt n, M. Jabeen n, n & B. Rao n
2023 article
An unbiased, automated platform for scoring dopaminergic neurodegeneration in C. elegans
Clark, A. S., Kalmanson, Z., Morton, K., Hartman, J., Meyer, J., & San-Miguel, A. (2023, February 3).
2023 article
An unbiased, automated platform for scoring dopaminergic neurodegeneration in C. elegans
Clark, A. S., Kalmanson, Z., Morton, K., Hartman, J., Meyer, J., & San-Miguel, A. (2023, July 7). (P. Lajoie, Ed.). PLoS ONE.
Ed(s): P. Lajoie
2023 article
An unbiased, automated platform for scoring dopaminergic neurodegeneration in C. elegans
San Miguel, A., Clark, A., Kalmanson, Z., Morton, K., Hartman, J., & Meyer, J. (2023, May 2). Dryad.
2023 article
Data for: Endogenous DAF-16 spatiotemporal activity quantitatively predicts lifespan extension induced by dietary restriction
Huayta, J., Crapster, J., & San Miguel, A. (2023, January 30). Dryad.
2023 article
Endogenous DAF-16 spatiotemporal activity quantitatively predicts lifespan extension induced by dietary restriction
Huayta, J., Crapster, J. P., & San-Miguel, A. (2023, February 20). Communications Biology, Vol. 6.
2023 article
Laminin switches terminal differentiation fate of human trophoblast stem cells under chemically defined culture conditions
Karakis, V., Jabeen, M., Britt, J. W., Cordiner, A., Mischler, A., Li, F., … Rao, B. M. (2023, March 25). Journal of Biological Chemistry, Vol. 299.
Contributors: V. Karakis n, M. Jabeen n, J. Britt n, A. Cordiner n, A. Mischler n, F. Li *, n , B. Rao n
2023 journal article
Molecular Engineering of Cyclic Azobenzene‐Peptide Hybrid Ligands for the Purification of Human Blood Factor VIII via Photo‐Affinity Chromatography
Advanced Functional Materials, 33(14), 2213881.
Contributors: R. Prodromou n, B. Moore n, W. Chu n, H. Deal n, n , A. Brown n , M. Daniele n , V. Pozdin*, S. Menegatti n
2023 article
Morphological hallmarks of dopaminergic neurodegeneration are associated with altered neuron function in Caenorhabditis elegans
Clark, A. S., Huayta, J., Morton, K. S., Meyer, J. N., & San-Miguel, A. (2023, August 23).
2023 article
Morphological hallmarks of dopaminergic neurodegeneration are associated with altered neuron function in Caenorhabditis elegans
Clark, A. S., Huayta, J., Morton, K. S., Meyer, J. N., & San-Miguel, A. (2023, December 7). NeuroToxicology, Vol. 100, pp. 100–106.
2023 article
Programming Probiotics: Diet-responsive gene expression and colonization control in engineered S. boulardii
Durmusoglu, D., Haller, D. J., Al’Abri, I. S., Day, K., Sands, C., Clark, A., … Crook, N. C. (2023, November 17).
2023 article
Sample numbers for Dopamine Added Swimming Induced Paralysis (DA-SWIP) and sorting experiments under 6-hydroxydopamine (6-OHDA)
Clark, A., Huayta, J., Morton, K., Meyer, J., & San Miguel, A. (2023, December 18). DRYAD.
Contributors: A. Clark n, J. Huayta *, K. Morton*, J. Meyer * & n
2022 article
Identifying C. elegans lifespan mutants by screening for early-onset protein aggregation
Midkiff, D. F., Huayta, J., Lichty, J. D., Crapster, J. P., & San-Miguel, A. (2022, October 28). IScience, Vol. 25, p. 105460.
2021 article
A bioinspired, passive microfluidic lobe filtration system
Clark, A. S., & San-Miguel, A. (2021, January 1). Lab on a Chip, Vol. 21, pp. 3762–3774.
2021 article
Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction
Arulalan, K. S., Huayta, J., Stallrich, J. W., & San-Miguel, A. (2021, March 19).
2021 journal article
Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction
Exposome, 1(1).
2021 article
Endogenous DAF-16 Spatiotemporal Activity Quantitatively Predicts Lifespan Extension Induced by Dietary Restriction
Huayta, J., & San-Miguel, A. (2021, December 21).
2021 journal article
Engineering Next Generation Cyclized Peptide Ligands for Light‐Controlled Capture and Release of Therapeutic Proteins
Advanced Functional Materials, 31(27), 2101410.
Contributors: R. Prodromou n, K. Day n, S. Saberi-Bosari n, J. Schneible n, M. Mabe n, n , M. Daniele n , V. Pozdin*, S. Menegatti n
2021 article
Identifying C. elegans Lifespan Mutants by Screening for Early-Onset Protein Aggregation
Midkiff, D. F., & San-Miguel, A. (2021, December 16).
2021 article
Local velocity of thermoresponsive colloidal gels in rate-driven flow
Smith, K. M., San-Miguel, A., & Hsiao, L. C. (2021, March 1). Physics of Fluids, Vol. 33, p. 033113.
2021 article
Microfluidic devices for imaging and manipulation of C. elegans
Clark, A. S., Huayta, J., Arulalan, K. S., & San-Miguel, A. (2021, January 1). Elsevier EBooks, pp. 295–321.
2021 article
Optogenetics gets the worm
San-Miguel, A. (2021, June 23). Science Robotics, Vol. 6.
2021 article
Two distinct trophectoderm lineage stem cells from human pluripotent stem cells
Mischler, A., Karakis, V., Mahinthakumar, J., Carberry, C. K., Miguel, A. S., Rager, J. E., … Rao, B. M. (2021, January 1). Journal of Biological Chemistry, Vol. 296, p. 100386.
Contributors: A. Mischler n, V. Karakis n, J. Mahinthakumar n, C. Carberry *, n , J. Rager *, R. Fry*, B. Rao n
2020 article
A reference map of the human binary protein interactome
Luck, K., Kim, D.-K., Lambourne, L., Spirohn, K., Begg, B. E., Bian, W., … Calderwood, M. A. (2020, April 8). Nature, Vol. 580, pp. 402–408.
2020 journal article
Additional file 1 of Deep learning-enabled analysis reveals distinct neuronal phenotypes induced by aging and cold-shock
Figshare.
2020 article
An inexpensive programmable optogenetic platform for controlled neuronal activation regimens in C. elegans
Crawford, Z., & San-Miguel, A. (2020, January 2). APL Bioengineering, Vol. 4, p. 016101.
2020 article
Deep learning-enabled analysis reveals distinct neuronal phenotypes induced by aging and cold-shock
Saberi-Bosari, S., Flores, K. B., & San-Miguel, A. (2020, September 23). BMC Biology, Vol. 18.
2020 article
Deep learning-enabled phenotyping reveals distinct patterns of neurodegeneration induced by aging and cold-shock
Saberi-Bosari, S., Flores, K. B., & San-Miguel, A. (2020, March 9).
2020 article
Genetic and Chemical Effects on Somatic and Germline Aging
Lee, M.-H., Luo, H.-R., Bae, S. H., & San-Miguel, A. (2020, January 4). Oxidative Medicine and Cellular Longevity, Vol. 2020, pp. 1–2.
2020 article
Lifelong Analysis of Key Aging Genes as Determinants of Lifespan in C. elegans
Miguel, A. S., Ramirez, J. H., & Flores, K. (2020, April 1). The FASEB Journal, Vol. 34.
2019 article
Affordable Microfluidic Bead-Sorting Platform for Automated Selection of Porous Particles Functionalized with Bioactive Compounds
Saberi-Bosari, S., Omary, M., Lavoie, A., Prodromou, R., Day, K., Menegatti, S., & San-Miguel, A. (2019, May 10). Scientific Reports, Vol. 9.
2019 article
Derivation of human trophoblast stem cells from human pluripotent stem cells
Mischler, A., Karakis, V., Miguel, A. S., & Rao, B. (2019, August 1). Placenta, Vol. 83, pp. E59–E59.
2019 article
Discovery and Evaluation of Peptide Ligands for Selective Adsorption and Release of Cas9 Nuclease on Solid Substrates
Day, K., Prodromou, R., Bosari, S. S., Lavoie, A., Omary, M., Market, C., … Menegatti, S. (2019, November 22). Bioconjugate Chemistry, Vol. 30, pp. 3057–3068.
2019 article
Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans
Midkiff, D., & San-Miguel, A. (2019, November 25). Molecules.
2018 article
A microfluidic platform for lifelong high-resolution and high throughput imaging of subtle aging phenotypes inC. elegans
Saberi-Bosari, S., Huayta, J., & San-Miguel, A. (2018, January 1). Lab on a Chip, Vol. 18, pp. 3090–3100.
2016 article
Deep phenotyping unveils hidden traits and genetic relations in subtle mutants
San-Miguel, A., Kurshan, P. T., Crane, M. M., Zhao, Y., McGrath, P. T., Shen, K., & Lu, H. (2016, November 23). Nature Communications, Vol. 7.
Contributors: * , P. Kurshan *, M. Crane *, Y. Zhao *, P. McGrath *, K. Shen *, H. Lu *
2016 article
Microfluidic Platforms for Quantitative Biology Studies in Model Organisms
Porto, D. A., Rouse, T. M., San-Miguel, A., & Lu, H. (2016, January 1). (C. Lu & S. S. Verbridge, Eds.). Microfluidic Methods for Molecular Biology, pp. 1–18.
Contributors: D. Porto *, T. Rouse *, * & H. Lu *
Ed(s): C. Lu & S. Verbridge
2015 journal article
An automated programmable platform enabling multiplex dynamic stimuli delivery and cellular response monitoring for high-throughput suspension single-cell signaling studies
Lab on a Chip, 15(6), 1497–1507.
Contributors: L. He*, A. Kniss*, * , T. Rouse *, M. Kemp * & H. Lu *
2015 journal article
Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders
Cell, 161(3), 647–660.
Contributors: N. Sahni *, S. Yi *, M. Taipale *, J. Bass *, J. Coulombe-Huntington *, F. Yang *, J. Peng *, J. Weile *
2013 article
In Vivo Neuron‐Wide Analysis of Synaptic Vesicle Precursor Trafficking
Maeder, C. I., San‐Miguel, A., Wu, E. Y., Lu, H., & Shen, K. (2013, December 9). Traffic, Vol. 15, pp. 273–291.
Contributors: C. Maeder *, * , E. Wu*, H. Lu * & K. Shen *
2013 article
Microfluidics as a tool for C. elegans research
San-Miguel, A., & Lu, H. (2013, September 24). WormBook, pp. 1–19.
Contributors: * & H. Lu *
2012 journal article
A generalized approach for measuring microcapsule permeability with Fluorescence Recovery After Photobleaching
Journal of Materials Science, 48(5), 2215–2223.
Contributors: J. Scrimgeour *, * , J. Curtis * & S. Behrens *
2012 journal article
Influence of Nanoscale Particle Roughness on the Stability of Pickering Emulsions
Langmuir, 28(33), 12038–12043.
Contributors: * & S. Behrens *
2011 journal article
Correction to “Correlating Aggregation Kinetics and Stationary Diffusion in Protein–Sodium Salt Systems Observed with Dynamic Light Scattering”
Correction to “Correlating Aggregation Kinetics and Stationary Diffusion in Protein–Sodium Salt Systems Observed with Dynamic Light Scattering.” The Journal of Physical Chemistry B, 115(36), 10778–10778.
2010 journal article
Correlating Aggregation Kinetics and Stationary Diffusion in Protein−Sodium Salt Systems Observed with Dynamic Light Scattering
The Journal of Physical Chemistry B, 114(12), 4383–4387.
Contributors: J. Rubin*, * , A. Bommarius * & S. Behrens *
2010 journal article
Permeability control in stimulus-responsive colloidosomes
Soft Matter, 7(5), 1948–1956.
Contributors: * & S. Behrens *
2010 journal article
Smart colloidosomes with a dissolution trigger
Soft Matter, 6(14), 3163.
Contributors: * , J. Scrimgeour *, J. Curtis * & S. Behrens *
Employment
Updated: August 16th, 2023 09:18
2023 - present
2016 - 2023
Education
Updated: December 10th, 2019 16:55
2007 - 2011
Funding History
Funding history based on the linked ORCID record. Updated: June 30th, 2025 09:29