Adriana San Miguel

Also known as: Adriana San-Miguel; Adriana San Miguel Delgadillo

https://orcid.org/0000-0003-0172-2163

microfluidics, systems biology, quantitative image analysis, phenotyping, neurobiology, aging

Works (37)

Updated: June 2nd, 2023 05:01

2023 article

An unbiased, automated platform for scoring dopaminergic neurodegeneration inC. elegans

Clark, A. S., Kalmanson, Z., Morton, K., Hartman, J., Meyer, J., & San-Miguel, A. (2023, February 3).

By: A. Clark n, Z. Kalmanson n, K. Morton*, J. Hartman*, J. Meyer* & A. San-Miguel n

Source: ORCID
Added: May 31, 2023

2023 journal article

Endogenous DAF-16 spatiotemporal activity quantitatively predicts lifespan extension induced by dietary restriction

COMMUNICATIONS BIOLOGY, 6(1).

Sources: Web Of Science, ORCID
Added: March 27, 2023

2023 article

Molecular Engineering of Cyclic Azobenzene-Peptide Hybrid Ligands for the Purification of Human Blood Factor VIII via Photo-Affinity Chromatography

Prodromou, R., Moore, B. D., Chu, W., Deal, H., San Miguel, A., Brown, A. C., … Menegatti, S. (2023, January 25). ADVANCED FUNCTIONAL MATERIALS, Vol. 1.

author keywords: affinity ligands; azobenzene-peptide hybrids; biomolecular recognition; factor VIII; photo-affinity chromatography
Sources: Web Of Science, ORCID
Added: February 20, 2023

2022 journal article

Identifying C. elegans lifespan mutants by screening for early-onset protein aggregation

ISCIENCE, 25(11).

By: D. Midkiff, J. Huayta, J. Lichty, J. Crapster & A. San-Miguel

Sources: Web Of Science, ORCID
Added: January 3, 2023

2021 article

A bioinspired, passive microfluidic lobe filtration system

Clark, A. S., & San-Miguel, A. (2021, August 11). LAB ON A CHIP, Vol. 21.

By: A. Clark & A. San-Miguel n

Sources: Web Of Science, ORCID
Added: August 30, 2021

2021 article

Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction

Arulalan, K. S., Huayta, J., Stallrich, J. W., & San-Miguel, A. (2021, March 19).

By: K. Arulalan n, J. Huayta n, J. Stallrich n & A. San-Miguel n

Source: ORCID
Added: May 31, 2023

2021 journal article

Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction

Exposome, 1(1).

By: K. Arulalan n, J. Huayta n, J. Stallrich n & A. San-Miguel n

Source: ORCID
Added: May 31, 2023

2021 article

Endogenous DAF-16 Spatiotemporal Activity Quantitatively Predicts Lifespan Extension Induced by Dietary Restriction

Huayta, J., & San-Miguel, A. (2021, December 21).

By: J. Huayta n & A. San-Miguel n

Source: ORCID
Added: May 31, 2023

2021 journal article

Engineering Next Generation Cyclized Peptide Ligands for Light-Controlled Capture and Release of Therapeutic Proteins

ADVANCED FUNCTIONAL MATERIALS, 31(27).

By: R. Prodromou, K. Day, S. Saberi-Bosari n, J. Schneible, M. Mabe n, A. San Miguel, M. Daniele, V. Pozdin, S. Menegatti

author keywords: azobenzene; cyclized peptide; light‐ controlled biorecognition; microfluidic devices; photochromic switch; photo‐ isomerization kinetics
Sources: Web Of Science, ORCID
Added: May 24, 2021

2021 article

Identifying C. elegans Lifespan Mutants by Screening for Early-Onset Protein Aggregation

Midkiff, D. F., & San-Miguel, A. (2021, December 16).

By: D. Midkiff n & A. San-Miguel n

Source: ORCID
Added: May 31, 2023

2021 journal article

Local velocity of thermoresponsive colloidal gels in rate-driven flow

PHYSICS OF FLUIDS, 33(3).

By: K. Smith n, A. San-Miguel n & L. Hsiao

Sources: Web Of Science, ORCID
Added: April 19, 2021

2021 chapter

Microfluidic devices for imaging and manipulation of C. elegans

In Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms (pp. 295–321).

By: A. Clark n, J. Huayta n, K. Arulalan n & A. San-Miguel n

Source: ORCID
Added: May 31, 2023

2021 article

Optogenetics gets the worm

San-Miguel, A. (2021, June 30). SCIENCE ROBOTICS, Vol. 6.

By: A. San-Miguel n

Sources: Web Of Science, ORCID
Added: August 16, 2021

2021 journal article

Two distinct trophectoderm lineage stem cells from human pluripotent stem cells

JOURNAL OF BIOLOGICAL CHEMISTRY, 296.

By: A. Mischler, V. Karakis, J. Mahinthakumar n, C. Carberry*, A. San Miguel, J. Rager*, R. Fry*, B. Rao

Sources: Web Of Science, ORCID
Added: September 7, 2021

2020 journal article

A reference map of the human binary protein interactome

Nature, 580(7803), 402–408.

Source: ORCID
Added: May 31, 2023

2020 journal article

An inexpensive programmable optogenetic platform for controlled neuronal activation regimens in C. elegans

APL BIOENGINEERING, 4(1).

By: Z. Crawford n & A. San-Miguel n

Sources: ORCID, Web Of Science
Added: April 20, 2020

2020 journal article

Deep learning-enabled analysis reveals distinct neuronal phenotypes induced by aging and cold-shock

BMC BIOLOGY, 18(1).

By: S. Saberi-Bosari n, K. Flores & A. San-Miguel n

author keywords: Deep learning; Convolutional neural networks; Neurodegeneration; Neuronal beading; Aging; Machine learning; Phenotyping; C; elegans
Sources: Web Of Science, ORCID
Added: October 26, 2020

2020 article

Deep learning-enabled phenotyping reveals distinct patterns of neurodegeneration induced by aging and cold-shock

Saberi-Bosari, S., Flores, K. B., & San-Miguel, A. (2020, March 9).

By: S. Saberi-Bosari n, K. Flores n & A. San-Miguel n

Source: ORCID
Added: May 31, 2023

2020 article

Genetic and Chemical Effects on Somatic and Germline Aging

Lee, M.-H., Luo, H.-R., Bae, S. H., & San-Miguel, A. (2020, January 4). OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, Vol. 2020.

Sources: Web Of Science, ORCID
Added: January 27, 2020

2020 article

Lifelong Analysis of Key Aging Genes as Determinants of Lifespan in C. elegans

San Miguel, A., Ramirez, J., & Flores, K. (2020, April). FASEB JOURNAL, Vol. 34.

By: A. San Miguel, J. Ramirez & K. Flores

Sources: Web Of Science, ORCID
Added: October 12, 2020

2019 journal article

Affordable Microfluidic Bead-Sorting Platform for Automated Selection of Porous Particles Functionalized with Bioactive Compounds

SCIENTIFIC REPORTS, 9(1).

By: S. Saberi-Bosari n, M. Omary n, A. Lavoie, R. Prodromou, K. Day, S. Menegatti, A. San-Miguel n

Sources: Web Of Science, ORCID
Added: May 28, 2019

2019 article

DERIVATION OF HUMAN TROPHOBLAST STEM CELLS FROM HUMAN PLURIPOTENT STEM CELLS

Mischler, A., Karakis, V., San Miguel, A., & Rao, B. (2019, August). PLACENTA, Vol. 83, pp. E59–E59.

By: A. Mischler, V. Karakis, A. San Miguel & B. Rao

Sources: Web Of Science, ORCID
Added: April 20, 2020

2019 journal article

Discovery and Evaluation of Peptide Ligands for Selective Adsorption and Release of Cas9 Nuclease on Solid Substrates

BIOCONJUGATE CHEMISTRY, 30(12), 3057–3068.

By: K. Day, R. Prodromou, S. Bosari n, A. Lavoie, M. Omary n, C. Market n, A. San Miguel, S. Menegatti

Sources: Web Of Science, ORCID
Added: January 13, 2020

2019 review

Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans

[Review of ]. MOLECULES, 24(23).

By: D. Midkiff n & A. San-Miguel n

author keywords: screening; microfluidics; phenotyping; genetics; aging
Sources: ORCID, Web Of Science
Added: February 3, 2020

2018 journal article

A microfluidic platform for lifelong high-resolution and high throughput imaging of subtle aging phenotypes in C-elegans

LAB ON A CHIP, 18(20).

By: S. Saberi-Bosari n, J. Huayta n & A. San-Miguel n

Sources: Web Of Science, ORCID
Added: November 12, 2018

2016 journal article

Deep phenotyping unveils hidden traits and genetic relations in subtle mutants

NATURE COMMUNICATIONS, 7.

By: A. San-Miguel n, P. Kurshan*, M. Crane*, Y. Zhao*, P. McGrath*, K. Shen*, H. Lu*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 chapter

Microfluidic Platforms for Quantitative Biology Studies in Model Organisms

In C. Lu & S. S. Verbridge (Eds.), Microfluidic Methods for Molecular Biology (pp. 1–18).

By: D. Porto*, T. Rouse*, A. San-Miguel* & H. Lu*

Ed(s): C. Lu* & S. Verbridge

Event: at Cham

Source: ORCID
Added: May 31, 2023

2015 journal article

An automated programmable platform enabling multiplex dynamic stimuli delivery and cellular response monitoring for high-throughput suspension single-cell signaling studies

Lab on a Chip, 15(6), 1497–1507.

By: L. He*, A. Kniss*, A. San-Miguel*, T. Rouse*, M. Kemp* & H. Lu*

Sources: Crossref, ORCID
Added: December 11, 2020

2015 journal article

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Cell, 161(3), 647–660.

By: N. Sahni*, S. Yi*, M. Taipale*, J. Fuxman Bass*, J. Coulombe-Huntington*, F. Yang*, J. Peng*, J. Weile* ...

Sources: Crossref, ORCID
Added: August 28, 2020

2014 journal article

In Vivo Neuron-Wide Analysis of Synaptic Vesicle Precursor Trafficking

Traffic, 15(3), 273–291.

By: C. Maeder*, A. San-Miguel*, E. Wu*, H. Lu* & K. Shen*

Source: ORCID
Added: May 31, 2023

2013 journal article

A generalized approach for measuring microcapsule permeability with Fluorescence Recovery After Photobleaching

Journal of Materials Science, 48(5), 2215–2223.

Sources: Crossref, ORCID
Added: December 11, 2020

2013 journal article

Microfluidics as a tool for C. elegans research.

WormBook : the Online Review of C. Elegans Biology, 1–19.

By: A. San-Miguel & H. Lu

Source: ORCID
Added: May 31, 2023

2012 journal article

Influence of Nanoscale Particle Roughness on the Stability of Pickering Emulsions

Langmuir, 28(33), 12038–12043.

By: A. San-Miguel* & S. Behrens

Sources: Crossref, ORCID
Added: August 28, 2020

2011 journal article

Correction to “Correlating Aggregation Kinetics and Stationary Diffusion in Protein–Sodium Salt Systems Observed with Dynamic Light Scattering”

Correction to “Correlating Aggregation Kinetics and Stationary Diffusion in Protein–Sodium Salt Systems Observed with Dynamic Light Scattering.” The Journal of Physical Chemistry B, 115(36), 10778–10778.

By: J. Rubin, A. San Miguel, A. Bommarius & S. Behrens

Sources: Crossref, ORCID
Added: August 28, 2020

2011 journal article

Permeability control in stimulus-responsive colloidosomes

Soft Matter, 7(5), 1948–1956.

By: A. San Miguel & S. Behrens*

Sources: Crossref, ORCID
Added: August 28, 2020

2010 journal article

Correlating Aggregation Kinetics and Stationary Diffusion in Protein−Sodium Salt Systems Observed with Dynamic Light Scattering

The Journal of Physical Chemistry B, 114(12), 4383–4387.

By: J. Rubin*, A. San Miguel, A. Bommarius* & S. Behrens*

Sources: Crossref, ORCID
Added: August 28, 2020

2010 journal article

Smart colloidosomes with a dissolution trigger

Soft Matter, 6(14), 3163.

By: A. San Miguel, J. Scrimgeour*, J. Curtis* & S. Behrens*

Sources: Crossref, ORCID
Added: August 28, 2020

Employment

Updated: February 9th, 2017 10:48

2016 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Chemical & Biomolecular Engineering

Education

Updated: December 10th, 2019 16:55

2007 - 2011

Georgia Institute of Technology Atlanta, GA, US
Ph.D. Chemical Engineering Chemical & Biomolecular Engineering

Instituto Tecnológico y de Estudios Superiores de Monterrey Monterrey, MX
BS. Chemical Engineering

Funding History

Funding history based on the linked ORCID record. Updated: October 5th, 2021 22:03

grant August 1, 2021 - July 1, 2025
IMAGiNE: Dissecting Neuronal and Systemic Responses to Interacting Environmental Stressors
National Science Foundation
grant December 15, 2019 - November 30, 2021
EAGER: Rapid evolution of enhancer DNA sequences in Drosophila
Directorate for Biological Sciences
grant January 15, 2019 - December 31, 2020
A platform for in vivo lifelong tracking of aging genes and lifespan prediction under precise environments in C. elegans.
National Institute on Aging
grant August 1, 2018 - July 1, 2020
RoL: FELS: EAGER Rules of lifespan determination and buffering from lifelong spatiotemporal activity of key aging pathways.
National Science Foundation
grant August 15, 2017 - July 31, 2020
A Microfluidics-Enabled In Vitro Model for Early Human Placental Development
National Science Foundation - Directorate for Engineering
grant October 1, 2016 - September 1, 2017
Exploring Synergies Among Neuronal Injury, Neurodegeneration, and Alzheimer's Disease with High-Throughput On-Chip Screening Platforms
Congressionally Directed Medical Research Programs
grant July 1, 2016 - April 30, 2019
Elucidating Synaptic Regulators via High-Throughput Morphology Characterization
National Institute on Aging
grant December 1, 2013 - December 31, 2015
Elucidating Synaptic Regulators via High-Throughput Morphology Characterization
National Institute on Aging
grant
High-Throughput, High-Dimensional (HT-HD) Phenotyping of C. elegans for ALS Drug Discovery
Congressionally Directed Medical Research Programs