Works (2)

Updated: July 5th, 2023 14:33

2021 journal article

Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 74(1), 194–210.

By: L. Griffin n, S. Kohrt*, A. Rathore n, C. Kay n, M. Grabowska* & A. Neilson n

MeSH headings : Animals; Chromatography, Liquid; Gastrointestinal Microbiome; Polyphenols / analysis; Rats; Tandem Mass Spectrometry; Urinary Bladder Neoplasms / drug therapy
TL;DR: It is suggested that microbial metabolites may be the primary compounds responsible for chemoprevention in uroepithelial cell following flavanol consumption, highlighting the potential for exploiting knowledge about individual genetics, microbiome profiles, flavonoid metabolism profiles, tumor characteristics, etc. to design personalized dietary interventions for cancer prevention and/or adjuvant therapy to reduce bladder cancer incidence and improve outcomes. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 10, 2021

2020 article

Supplemental treatment options for diabetes: how flavanol metabolites improve beta-cell function

Lloyd, T., Griffin, L., Krueger, E., Beales, J., Barlow, A., Sheets, J., … Tessem, J. (2020, April). FASEB JOURNAL, Vol. 34.

By: T. Lloyd*, L. Griffin n, E. Krueger*, J. Beales*, A. Barlow*, J. Sheets*, I. Ekpo*, M. Ross* ...

TL;DR: Data is presented regarding the in vitro effects of these absorbed gut bacteria derived flavanoids on INS‐1 832/13 β‐cell insulin secretion and proliferation and further light is shed on the potential ability of flavanoid and their gut bacteriaderived metabolites to enhance functional β‐ cell mass. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 12, 2020

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